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CRBP

Corbus Pharmaceuticals

$6.91

-0.31 (-4.29%)

08:11
04/18/19
04/18
08:11
04/18/19
08:11

Corbus Pharmaceuticals changes primary endpoint in RESOLVE-1 trial to ACR CRISS

Corbus Pharmaceuticals announced that following a Type C meeting with the FDA, Corbus will change the primary efficacy endpoint of the ongoing RESOLVE-1 Phase 3 trial for systemic sclerosis, or SSc, in the U.S. to the American College of Rheumatology Combined Response Index in diffuse cutaneous Systemic Sclerosis, or ACR CRISS, score at Week 52 from the current primary endpoint, change in modified Rodnan Skin core, or mRSS. The ACR CRISS score was the primary efficacy endpoint of the Phase 2 study evaluating lenabasum for the treatment of diffuse cutaneous SSc. The company remains on track to complete the RESOLVE-1 study in the first half of 2020 and no changes to the size or length of the study are required. The ACR CRISS score provides a measure of response to treatment compared to mRSS, which only measures skin thickening. The ACR CRISS score is calculated from weighted changes from baseline in five core outcome measures commonly used to evaluate treatment effect in trials for SSc.

CRBP Corbus Pharmaceuticals
$6.91

-0.31 (-4.29%)

03/18/19
OPCO
03/18/19
INITIATION
Target $28
OPCO
Outperform
Corbus Pharmaceuticals initiated with an Outperform at Oppenheimer
Oppenheimer initiated Corbus Pharmaceuticals with an Outperform and $28 price target
03/19/19
OPCO
03/19/19
INITIATION
Target $28
OPCO
Outperform
Corbus jumps over 10% after Oppenheimer starts with $28 price target
Shares of Corbus Pharmaceuticals are moving higher after Oppenheimer analyst Leland Gershell initiated coverage of the name with an Outperform rating and $28 price target. The stock in early trading is up 10%, or 69c, to $7.56. The next 12-24 months could be transformational for Corbus, as ongoing late-stage trials of lead oral cannabinoid receptor agonist lenabasum in three "rare, poorly met disorders" of chronic inflammation/fibrosis complete their enrollment and deliver top-line data, Gershell told investors last night in a research note. Results from the 350 patient Resolve-1 trial, expected in mid-2020, could enable lenabasum to address a ~920M market opportunity, contends the analyst. Further, lenabasum has demonstrated positive prior clinical data in dermatomyositis and cystic fibrosis as well, each of which offers $500M to $1B in sales potential, according to Gershell.
04/05/19
JEFF
04/05/19
INITIATION
Target $18
JEFF
Buy
Corbus Pharmaceuticals initiated with a Buy at Jefferies
Jefferies analyst Maury Raycroft initiated Corbus Pharmaceuticals with a Buy rating and $18 price target.
04/05/19
04/05/19
INITIATION

Fly Intel: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Wex (WEX) initiated with a Neutral at Baird. 2. Restaurant Brands (QSR) initiated with an Outperform at Bernstein. 3. Corbus Pharmaceuticals (CRBP) initiated with a Buy at Jefferies. 4. Trex Company (TREX) initiated with a Buy at DA Davidson. 5. Regis (RGS) initiated with a Buy at Loop Capital. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

ATRC

AtriCure

$30.99

1.29 (4.34%)

04:55
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AtriCure management to meet with JPMorgan »

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ACAD

Acadia

$51.37

0.915 (1.81%)

, AMGN

Amgen

$233.74

0.3 (0.13%)

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Clinical Trials on Alzheimer's Disease to hold conference »

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Acadia

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0.915 (1.81%)

AMGN

Amgen

$233.74

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AZN

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$47.68

0.06 (0.13%)

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Biogen

$300.27

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CLB

Core Laboratories

$46.19

1.94 (4.38%)

DNA

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ESALY

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$0.00

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JNJ

Johnson & Johnson

$140.36

0.79 (0.57%)

LLY

Eli Lilly

$119.59

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MRK

Merck

$88.84

0.09 (0.10%)

NVS

Novartis

$92.08

0.42 (0.46%)

RHHBY

Roche

$0.00

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TAK

Takeda Pharmaceutical

$20.27

-0.16 (-0.78%)

VCNX

Vaccinex

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MGTA

Magenta Therapeutics

$13.29

0.3 (2.31%)

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Magenta Therapeutics to hold an investor and analyst event »

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JPMorgan enterprise software analyst to hold an analyst/industry conference call »

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RUHN

Ruhnn

$6.19

-0.2 (-3.13%)

04:55
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Ruhnn management to meet with Mizuho »

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FITB

Fifth Third

$30.24

0.365 (1.22%)

, CSCO

Cisco

$43.83

0.29 (0.67%)

18:37
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Hot Stocks
Fifth Third issues statement on temporary network outage »

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FITB

Fifth Third

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CSCO

Cisco

$43.83

0.29 (0.67%)

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STML

Stemline

$10.33

0.5 (5.09%)

, PFE

Pfizer

$38.29

0.26 (0.68%)

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Stemline names Robert Francomano as Chief Commercial Officer »

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STML

Stemline

$10.33

0.5 (5.09%)

PFE

Pfizer

$38.29

0.26 (0.68%)

GSK

GlaxoSmithKline

$45.51

0.29 (0.64%)

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GOL

Gol Linhas

$17.39

1.07 (6.56%)

18:31
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Gol Linhas announces preliminary traffic figures for November »

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NAVB

Navidea

$0.97

0.07 (7.78%)

18:25
12/06/19
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18:25
Syndicate
Navidea announces $1.9M private placement »

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EFC

Ellington Financial

$18.22

0.09 (0.50%)

18:23
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Ellington Financial reports estimated book value per share $18.51 on November 30 »

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BOOT

Boot Barn

$41.93

0.81 (1.97%)

18:22
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Boot Barn CEO: More than 80% of our business is in the store »

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ERIC

Ericsson

$9.24

0.1 (1.09%)

18:18
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Ericsson to pay over $1B to settle FCPA case »

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GLD

SPDR Gold Shares

$137.59

-1.42 (-1.02%)

17:55
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SPDR Gold Shares holdings fall to 886.23MT from 888.57MT »

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PICO

PICO Holdings

$10.81

0.31 (2.95%)

17:45
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PICO Holdings sells long-term storage credits for $8.7M in Arizona »

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QHC

Quorum Health

$0.95

0.0522 (5.81%)

17:31
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Quorum Health receives NYSE continued listing standard notice »

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SPRT

Support.com

$1.94

0.01 (0.52%)

17:30
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17:30
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Breaking Hot Stocks news story on Support.com »

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BXRX

Baudax Bio

$6.69

0.34 (5.35%)

17:29
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17:29
Syndicate
Breaking Syndicate news story on Baudax Bio »

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LMT

Lockheed Martin

$387.10

1.175 (0.30%)

17:25
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Lockheed Martin awarded $153.39M Navy contract modification »

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ENV

Envestnet

$71.72

1.27 (1.80%)

17:23
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17:23
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Breaking Syndicate news story on Envestnet »

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NOC

Northrop Grumman

$344.79

0.4 (0.12%)

17:20
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Northrop Grumman awarded $189M Navy contract modification »

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SPRT

Support.com

$1.94

0.01 (0.52%)

17:03
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Support.com announces special distribution of $1.00 per share »

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SPRT

Support.com

$1.94

0.01 (0.52%)

17:01
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Breaking Hot Stocks news story on Support.com »

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RZLT

Rezolute

$0.00

(0.00%)

17:00
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17:00
Syndicate
Breaking Syndicate news story on Rezolute »

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AMZN

Amazon.com

$1,750.79

10.2 (0.59%)

16:58
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12/06
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Periodicals
U.S. mulls putting Amazon foreign sites on 'Notorious Markets' list, WSJ says »

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MGTA

Magenta Therapeutics

$13.29

0.3 (2.31%)

16:55
12/06/19
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Conference/Events
Magenta Therapeutics to hold an investor and analyst event »

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