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WVE

Wave Life Sciences

$27.21

1.43 (5.55%)

11:50
04/23/19
04/23
11:50
04/23/19
11:50

Call buy in Wave Life will create its largest open interest

Call buy in Wave Life will create its largest open interest. Shares up 5.2% to $27.13 and 3K Jan 35s trade $5.95 per contract. The $1.7M option print opens a position struck 29% above spot and comes ahead of earnings, due around 5/9. The stock was north of $42 on 4/9, but has seen a steady wave of selling since then on disappointing clinical trial data for one its drugs.

WVE Wave Life Sciences
$27.21

1.43 (5.55%)

04/16/19
STFL
04/16/19
DOWNGRADE
STFL
Hold
Wave Life Sciences downgraded to Hold from Buy at Stifel
04/16/19
04/16/19
DOWNGRADE

Hold
Wave Life Sciences downgraded to Hold from Buy at Stifel
As previously reported, Stifel analyst Paul Matteis downgraded Wave Life Sciences to Hold from Buy, and reduced his target price on shares to $26 from $53. The analyst believes the company's Duchenne muscular dystrophy, or DMD, update from this morning "raises concerns around suvodirsen and more broadly, the degree to which leveraging stereochemistry will lead to a differentiated ASO-based medicines." While Matteis still sees Huntington's disease as a potential source of upside for the stock, the "recent delay -- especially in light of the DMD update this morning -- has reduced [the analyst's] level of conviction in Wave management's execution and the bull-case on its platform/technology."
04/17/19
HCWC
04/17/19
NO CHANGE
Target $33
HCWC
Buy
Wave Life Sciences price target lowered to $33 from $49 at H.C. Wainwright
H.C. Wainwright analyst Debjit Chattopadhyay lowered his price target for Wave Life Sciences to $33 from $49 following the first look at the company's stereopure isomer platform with a preliminary read on safety and dose for the planned Phase 2/3 program from patients amenable to exon 51 skipping. The analyst believes Wave has a "lot to prove" with limited near-term catalysts. Nonetheless, he keeps a Buy rating on the stock.
04/18/19
MZHO
04/18/19
NO CHANGE
Target $65
MZHO
Buy
Mizuho defends Wave Life Sciences, says suvodirsen not drisapersen
Mizuho analyst Salim Syed yesterday afternoon came out "defending" shares of Wave Life Sciences (WVE) following the recent selloff. The reaction has been based on false logic, primarily equating Wave Life's suvodirsen to BioMarin's (BMRN) failed drisapersen, Syed told investors in a research note. Suvodirsen "is NOT" drisapersen and the lower suvodirsen Phase 2/3 dosing versus drisapersen's "does not necessarily imply a lesser or even similar dystrophin expression," Syed wrote. Further, the Phase 2/3 dosing "was selected rationally, seems within the therapeutic window, and is likely favorable to current standard of care," he contends. The analyst adds that the Phase 1 safety data "was still generally clean." Syed keeps a Buy rating on Wave Life Sciences with a $65 price target.

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$NSD

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$NYE

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RHE

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