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ABBV

AbbVie

$78.65

0.55 (0.70%)

18:21
04/23/19
04/23
18:21
04/23/19
18:21

AbbVie says FDA approves SKYRIZI

AbbVie announced that the U.S. Food and Drug Administration approved SKYRIZI, an interleukin-23 inhibitor, for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy. In clinical trials, SKYRIZI produced high rates of durable skin clearance - most people treated with SKYRIZI achieved 90% skin clearance at one year, with the majority achieving complete skin clearance. "The complex nature of psoriasis and the variability or loss of treatment response over time can prevent some patients from achieving their treatment goals," said Kenneth B. Gordon, M.D., a principal investigator for the ultIMMa-1 pivotal trial and professor and chair of dermatology at the Medical College of Wisconsin. "In clinical trials, risankizumab demonstrated high levels of skin clearance that persisted through one year. I'm pleased the dermatology community now has a new option that can help patients achieve and maintain a high level of treatment response." SKYRIZI is expected to be available in the U.S. in early May.

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ABBV AbbVie
$78.65

0.55 (0.70%)

04/11/19
EVER
04/11/19
INITIATION
Target $30
EVER
Outperform
Myovant Sciences initiated with an Outperform at Evercore ISI
Evercore ISI analyst Ravi Mehrotra initiated Myovant Sciences (MYOV) with an Outperform rating and a price targets of $30. The analyst says the company's lead program relugolix has been clinically de-risked with near-term pivotal data readouts. Mehrotra is modeling revenues of $944M for the program by 2023 thanks to its "commercial advantage of a one-a-day pill" and the "second-mover leverage of competitor AbbVie's (ABBV) efforts to raise awareness and diagnosis" in woman's health market.
03/26/19
WBLR
03/26/19
UPGRADE
WBLR
Outperform
William Blair upgrades Vertex to Outperform after 'subpar' competitor data
William Blair analyst Y. Katherine Xu upgraded Vertex Pharmaceuticals (VRTX) to Outperform from Market Perform on expectations the company's cystic fibrosis franchise will continue dominating after Proteostasis (PTI) reported disappointing triplet data. Proteostasis' triplet efficacy falls short of the high bar set by the Vertex triples, Xu tells investors in a research note. While Proteostasis is starting a Phase II study of the triplet that would include a higher PTI-808 dose and test a longer duration aiming to optimize response with data out around year-end 2019, the chance of it matching or exceeding Vertex triple efficacy is "very low," contends the analyst. With both Galapagos (GLPG)/AbbVie (ABB) and Proteostasis having shown "subpar data," Xu is upgrading Vertex shares to Outperform and raised her fair value estimate for the shares to $222 from $178. The analyst maintains her high probability of success of a Vertex triple combo reaching the cystic fibrosis market at 90% and ascribe peak sales of $10.2B, up from $8.9 billion previously.
03/25/19
03/25/19
DOWNGRADE

Hold
AbbVie downgraded to Hold from Buy at Argus
As previously reported, Argus analyst David Toung downgraded AbbVie to Hold, saying its flagship program Humira "no longer looks invulnerable to competition from biosimilars in Europe and other overseas markets." The analyst notes that Humira is also faced with "indirect competition from newer drugs that have an alternative mechanism of action" compared to Humira's anti-TNF class. Toung further cites AbbVie's clinical setback with Venclexta, which highlights the risks for the company as it develops a pipeline aimed to offset the expected decline in Humira sales.
03/25/19
ARGS
03/25/19
DOWNGRADE
ARGS
Hold
AbbVie downgraded to Hold from Buy at Argus

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YGYI

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YGYI

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QFIN

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VAR

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TOL

Toll Brothers

$37.52

-0.88 (-2.29%)

18:47
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Toll Brothers acquires Sharp Residential, terms not disclosed »

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General news
Breaking General news story  »

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TTWO

Take-Two

$102.94

-3.82 (-3.58%)

18:44
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Take-Two CEO: Our job is to excite customers »

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AAL

American Airlines

$30.96

-0.8 (-2.52%)

18:40
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Periodicals
American Air asks court to halt alleged mechanics unions' slowdown, Reuters says »

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LWAY

Lifeway Foods

$2.75

0.05 (1.85%)

18:38
05/20/19
05/20
18:38
05/20/19
18:38
Earnings
Lifeway Foods reports Q1 EPS (2c) vs. 0c last year »

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WHLR

Wheeler REIT

$2.25

0.025 (1.13%)

18:31
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Wheeler REIT chairman John Sweet to resign »

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WMT

Walmart

$101.54

0.66 (0.65%)

, TGT

Target

$72.10

1.22 (1.72%)

18:03
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Periodicals
Judge says Walmart, Target, Bed Bath must face suits over cotton, Reuters says »

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WMT

Walmart

$101.54

0.66 (0.65%)

TGT

Target

$72.10

1.22 (1.72%)

BBBY

Bed Bath & Beyond

$14.48

-0.525 (-3.50%)

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QFIN

360 Finance

$16.46

0.71 (4.51%)

18:02
05/20/19
05/20
18:02
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18:02
Earnings
360 Finance reports Q1 net income $117.5M, up 382% from last year »

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MRK

Merck

$78.86

0.15 (0.19%)

18:02
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PRIM

Primoris

$20.26

-0.08 (-0.39%)

17:55
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Primoris director sells 99.8K shares of common stock »

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BK

BNY Mellon

$45.97

-0.11 (-0.24%)

, LM

Legg Mason

$35.68

0.295 (0.83%)

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BK

BNY Mellon

$45.97

-0.11 (-0.24%)

LM

Legg Mason

$35.68

0.295 (0.83%)

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DHR

Danaher

$130.33

-0.81 (-0.62%)

17:44
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VP of Danaher Angela Lalor sells over $408K in company shares »

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SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$283.95

-2.03 (-0.71%)

17:43
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17:43
Periodicals
Judge dismisses Trump request to block accounting subpoena, WSJ says »

U.S. District Judge Amit…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$283.95

-2.03 (-0.71%)

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LM

Legg Mason

$35.68

0.295 (0.83%)

17:40
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Legg Mason names Nelson Peltz, Ed Garden to board of directors »

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XYF

X Financial

$5.42

0.1 (1.88%)

17:34
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Earnings
X Financial reports Q1 EPS 24c, consensus 24c »

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KTB

Kontoor Brands

$0.00

(0.00%)

, ORN

Orion Group

$2.31

0.02 (0.87%)

17:31
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Hot Stocks
S&P announces changes to S&P SmallCap 600 index »

S&P Dow Jones Indices…

KTB

Kontoor Brands

$0.00

(0.00%)

ORN

Orion Group

$2.31

0.02 (0.87%)

VFC

VF Corp.

$90.70

-0.08 (-0.09%)

ARWR

Arrowhead

$18.94

-0.52 (-2.67%)

NAVG

Navigators

$69.99

-0.01 (-0.01%)

HIG

Hartford Financial

$53.13

-0.45 (-0.84%)

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BYND

Beyond Meat

$86.10

-3.23 (-3.62%)

17:29
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Beyond Meat appoints Teri Witteman as General Counsel and Secretary »

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  • 06

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ARWR

Arrowhead

$18.94

-0.52 (-2.67%)

, NAVG

Navigators

$69.99

-0.01 (-0.01%)

17:27
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Hot Stocks
Arrowhead to replace Navigators in S&P 600 at open on 5/24 »

The Hartford Financial…

ARWR

Arrowhead

$18.94

-0.52 (-2.67%)

NAVG

Navigators

$69.99

-0.01 (-0.01%)

HIG

Hartford Financial

$53.13

-0.45 (-0.84%)

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  • 11

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YGYI

Youngevity

$6.57

0.13 (2.02%)

17:25
05/20/19
05/20
17:25
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17:25
Earnings
Breaking Earnings news story on Youngevity »

Youngevity backs FY19…

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KTB

Kontoor Brands

$0.00

(0.00%)

, ORN

Orion Group

$2.31

0.02 (0.87%)

17:25
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17:25
Hot Stocks
Kontoor Brands to replace Orion Group in S&P 600 at open on 5/24 »

V.F. Corp. (VFC) is…

KTB

Kontoor Brands

$0.00

(0.00%)

ORN

Orion Group

$2.31

0.02 (0.87%)

VFC

VF Corp.

$90.70

-0.08 (-0.09%)

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YGYI

Youngevity

$6.57

0.13 (2.02%)

17:25
05/20/19
05/20
17:25
05/20/19
17:25
Earnings
Youngevity reports Q1 EPS (49c), one estimate (1c) »

Reports Q1 revenue…

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GD

General Dynamics

$169.34

2.95 (1.77%)

17:22
05/20/19
05/20
17:22
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17:22
Hot Stocks
General Dynamics awarded $497.01M Navy contract modification »

General Dynamics has been…

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ISRL

Isramco, Inc.

$110.20

-2.05 (-1.83%)

17:18
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17:18
Hot Stocks
Isramco enters into $121.40 per share merger pact with Naphtha Israel Petroleum »

Isramco announced that it…

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PCH

PotlatchDeltic

$36.17

-1.31 (-3.50%)

17:16
05/20/19
05/20
17:16
05/20/19
17:16
Hot Stocks
PotlatchDeltic announces changes to Idaho recreation permits »

PotlatchDeltic announced…

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