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PRVB

Provention Bio

$3.31

0.12 (3.76%)

07:17
04/24/19
04/24
07:17
04/24/19
07:17

Provention Bio completes enrollment of Phase 2a Crohn's Disease candidate trial

Provention Bio has completed the enrollment in its Phase 2a PRINCE - PRovention Investigation in Crohn's DiseasE - clinical trial evaluating PRV-6527 in patients with moderate-to-severe Crohn's disease. "The on-schedule completion of enrollment in the PRINCE study for PRV-6527 is yet another significant executional achievement and operational milestone in our mission to develop therapeutics that intercept or prevent immune-mediated diseases," said Ashleigh Palmer, CEO of Provention Bio. "In prior studies, PRV-6527 demonstrated proof of mechanism with evidence of tolerability and favorable pharmacology. The results from the PRINCE study may establish the potential of this oral candidate in Crohn's disease, an indication which is currently dominated by biologics that offer limited benefit over the long-term. We look forward to reporting top-line data in Q4." The primary endpoint will assess clinical effect as measured by the Crohn's Disease Activity Index score at week 12. PRV-6527 was developed by Janssen Pharmaceuticals and has been evaluated in over 200 subjects to date.

PRVB Provention Bio
$3.31

0.12 (3.76%)

01/18/19
HCWC
01/18/19
INITIATION
Target $7.5
HCWC
Buy
Provention Bio initiated with a Buy at H.C. Wainwright
H.C. Wainwright analyst Raghuram Selvaraju started Provention Bio with a Buy rating and $7.50 price target. Provention is a "virtual, rapidly emerging biotechnology company focused on treatment of inflammatory and autoimmune diseases," Selvaraju tells investors in a research note. He sees "substantial" market opportunities for the company that underserved by existing drugs.
02/22/19
LEER
02/22/19
INITIATION
Target $6
LEER
Outperform
Provention Bio initiated with an Outperform at SVB Leerink
SVP Leerink analyst Pasha Sarraf initiated Provention Bio with an Outperform rating and $6 price target. The company's small team of experienced drug developers is aggregating assets through leveraged strategic partnerships, Sarraf tells investors in a research note.

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