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SBBP

Strongbridge Biopharma

$4.73

0.06 (1.28%)

16:05
04/25/19
04/25
16:05
04/25/19
16:05

Strongbridge Biopharma presents new secondary endpoint data on SONICS trial

Strongbridge Biopharma announced the presentation of new secondary endpoint results from the Phase 3 SONICS study of Recorlev for the potential treatment of endogenous Cushing's syndrome at the 2019 American Association of Clinical Endocrinologists, or AACE, annual scientific and clinical congress. Six-months of maintenance Recorlev therapy led to significant improvements in the clinical signs and symptoms of Cushing's syndrome including acne, hirsutism in women and peripheral edema. A reduction in mean free-testosterone in women, consistent with improvements in clinical signs of hyperandrogenism was observed, and a modest increase in mean free-testosterone in men was observed. Significant mean improvements in patient-reported quality-of-life outcomes were observed and symptoms of depression improved. Recorelv was generally well-tolerated, with 12.8% of patients discontinuing treatment due to an adverse event through the end of the six-month maintenance phase.

  • 01

    May

SBBP Strongbridge Biopharma
$4.73

0.06 (1.28%)

12/18/18
LDLW
12/18/18
INITIATION
Target $11
LDLW
Buy
Strongbridge Biopharma initiated with a Buy at Laidlaw
Laidlaw analyst Francois Brisebois started Strongbridge Biopharma with a Buy rating and $11 price target, stating that he views the stock as undervalued at current levels given what he sees as "strong" PHASE 3 Recorlev data and the "impressive commercial potential" of Macrilen.
11/01/18
STFL
11/01/18
NO CHANGE
Target $15
STFL
Buy
Stifel says Strongbridge makes 'right move' to improve Recorlev clinical package
Stifel analyst Annabel Samimy acknowledged that Recorlev development timelines are pushed out by Strongbridge Biopharma (SBBP) expanding LOGICS to strengthen the clinical package. While this results in a three-quarter delay, with top-line now expected in the fourth quarter of 2019 and the launch expectation pushed out to 2021, he believes the company is ultimately making "the right move." He added that the sale of North American rights of Macrelin to Novo Nordisk (NVO) represents a 7.5x return in less than 2 years, but that was overshadowed by Q3 results that showed Keveyis adoption is "proving more challenging." Samimy keeps a Buy rating and $15 price target on Strongbridge Biopharma shares.
08/08/18
JANY
08/08/18
NO CHANGE
Target $16
JANY
Buy
Strongbridge price target raised to $16 from $13 at Janney Montgomery Scott
Janney Montgomery Scott analyst Esther Hong raised her fair value estimate on Strongbridge Biopharma to $16 after the company announced its Phase 3 SONICS study of recorlev in Cushing's syndrome achieved the primary endpoint of normalized UFC during a 6-month period without a dose increase. Hong, who believes recorlev's demonstration of a clinically meaningful impact on comorbidities and a more favorable liver-tolerability profile compared to ketoconazole will drive uptake, keeps a Buy rating on Strongbridge shares.
06/28/18
JANY
06/28/18
INITIATION
Target $13
JANY
Buy
Strongbridge Biopharma initiated with a Buy at Janney
Janney initiated Strongbridge Biopharma with a Buy and $13 price target.

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