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TCRR

TCR2 Therapeutics

$16.20

-0.74 (-4.37%)

07:28
05/07/19
05/07
07:28
05/07/19
07:28

TCR2 Therapeutics announces publication of preclinical data on TRuC-T study

TCR2 Therapeutics announced online publication of preclinical data in Nature Communications. The paper is entitled, "Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response," and shows in several mouse models a higher anti-tumor activity of the company's proprietary T cell receptor, or TCR, fusion construct T cells, or TRuC-T cells compared to chimeric antigen receptor, or CAR,-T cells. The findings suggest profound differences in signaling between TRuC-T and CAR-T cells.

  • 13

    May

TCRR TCR2 Therapeutics
$16.20

-0.74 (-4.37%)

03/11/19
WEDB
03/11/19
INITIATION
Target $28
WEDB
Outperform
TCR2 Therapeutics initiated with an Outperform at Wedbush
Wedbush analyst David Nierengarten initiated TCR2 Therapeutics with an Outperform rating and $28 price target. In a research note to investors, Nierengarten contends that shares are undervalued based onhis positive outlook on the company's potentially best-in-class CAR-T cell platform, which is developing T-cell receptor Fusion Construct T cells, or TRuC-T cells,for both solid tumor and hematologic malignancies. To date, the platform has generated one clinical and two near-clinicalproduct candidates, including TC-210, currently in Ph 1 for mesothelin-expressing solid tumors, and TC-110 and TC-220, which are both in IND-enabling studies for CD19-positive B-cell malignancies and MUC16-expressing solid tumors.
03/11/19
JEFF
03/11/19
INITIATION
Target $31
JEFF
Buy
Jefferies starts TCR2 Therapeutics with Buy rating, $31 price target
Jefferies analyst Biren Amin initiated coverage of TCR2 Therapeutics with a Buy rating and $31 price target. The company is developing a "broad pipeline" centered on its TRuC technology that endows certain advantageous properties to T-cells for targeting solid tumors, where CAR-Ts have not seen much success, Amin tells investors in a research note. While early in development, the analyst believes TCR2 may offer a differentiated approach.
03/11/19
LEER
03/11/19
INITIATION
Target $27
LEER
Outperform
TCR2 Therapeutics initiated with an Outperform at SVB Leerink
SVB Leerink analyst Jonathan Chang initiated TCR2 Therapeutics with an Outperform rating and $27 price target. In a research note to investors, Chang says he has received positive feedback from MEDACorp Key Opinion Leaders on the company's T-Cell Receptor Fusion Construct pipeline based on the preclinical data to date that highlights the potential of TCR2's approach. The analyst maintains a positive long-term view of the stock based on the experienced management team and potentially transformative platform with broad therapeutic applicability.
03/11/19
03/11/19
INITIATION

Fly Intel: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. TCR2 Therapeutics (TCRR) initiated with an Outperform at SVB Leerink, Wedbush, and BMO Capital, while being initiated with a Buy at Jefferies. 2. Barings BDC (BBDC) resumed with an Outperform at Wells Fargo. 3. Avedro (AVDR) initiated with an Overweight at JPMorgan while being initiated with an Outperform at SVB Leerink and Cowen. 4. Anchiano Therapeutics (ANCN) initiated with a Buy at Ladenburg and an Outperform at Oppenheimer. 5. CytomX Therapeutics (CTMX) initiated with an Overweight at Barclays. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

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