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CELG

Celgene

$96.46

-0.38 (-0.39%)

07:47
05/07/19
05/07
07:47
05/07/19
07:47

Celgene says analysis shows oral ozanimod reduced brain volume loss

Celgene Corporation announced the results of a post-hoc analysis of data from the Phase 3 RADIANCE Part B trial showing that ozanimod reduced cortical grey matter volume loss versus first-line treatment, Avonex, in adults with relapsing multiple sclerosis across all age groups, including patients ages 18 to 25. The analysis will be presented at the 2019 American Academy of Neurology Annual Meeting in Philadelphia, May 4-10, 2019. RADIANCE evaluated two doses of oral ozanimod compared with interferon beta-1a in 1,313 patients with RMS between the ages of 18 and 55 years old. In this post-hoc analysis of 874 patients, treatment effect on serial brain volume, including thalamic volume and cortical grey matter, was evaluated by patient age at baseline, 12 months and 24 months. Patients in the 18 to 25 age group tended to have greater brain volume at baseline but more active disease as measured by gadolinium-enhancing MRI lesions. There was also a trend for this age group to experience greater whole brain volume loss at both 12 and 24 months compared with the older groups. Patients across all age groups treated with ozanimod lost less cortical grey matter volume than did those treated with interferon beta-1a over 24 months, including patients in the 18 to 25 age group. In the RADIANCE Part B trial, the most common adverse reactions that were higher with ozanimod than with interferon beta-1a were upper respiratory tract infections, urinary tract infections, increases of alanine aminotransferase and increases of gamma-glutamyl transferase.

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CELG Celgene
$96.46

-0.38 (-0.39%)

04/05/19
CANT
04/05/19
DOWNGRADE
Target $100
CANT
Neutral
Cantor sees Bristol deal closing, downgrades Celgene to Neutral
Cantor Fitzgerald analyst Alethia Young downgraded Celgene (CELG) to Neutral from Overweight with an unchanged price target of $100. The analyst expects the takeover by Bristol-Myers (BMY) to close.
05/03/19
LEHM
05/03/19
UPGRADE
Target $55
LEHM
Overweight
Bristol-Myers upgraded to Overweight from Equal Weight at Barclays
Barclays analyst Geoffrey Meacham upgraded Bristol-Myers Squibb (BMY) to Overweight from Equal Weight and raised his price target for the shares to $55 from $53. The analyst says increased confidence in the Celgene (CELG) acquisition successfully closing makes him more bullish on Bristol-Myers shares. Increased optionality from the Celgene pipeline along with a "differentiated" growth profile and earnings power over the next few years make the combined company attractive at current share levels, Meacham tells investors in a research note.
05/03/19
LEHM
05/03/19
DOWNGRADE
Target $102
LEHM
Equal Weight
Celgene downgraded to Equal Weight from Overweight at Barclays
Barclays analyst Geoffrey Meacham downgraded Celgene (CELG) to Equal Weight from Overweight to reflect his increased confidence that the takeover by Bristol-Myers (BMY) will close. The analyst, who upgraded Bristol-Myers this morning to Overweight, says his thesis on Celgene has played out. He keeps a $102 price target for the shares.
05/03/19
JPMS
05/03/19
INITIATION
Target $62
JPMS
Overweight
Bristol-Myers reinstated with an Overweight at JPMorgan
Following a period of restriction, JPMorgan analyst Chris Schott reinstated coverage of Bristol-Myers Squibb (BMY) with an Overweight rating and $62 price target. The analyst had an Overweight rating on the shares and price target of $70 prior to restriction. While the company's proposed acquisition of Celgene (CELG) has been controversial, the shares are "too inexpensive to ignore," Schott tells investors in a research note. He sees the combined company generating 2020 earnings of $6.50 per share and 3% sales/6% earnings growth off of this base through 2025.

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GM

General Motors

$35.13

0.01 (0.03%)

, TSLA

Tesla

$190.80

-4.7 (-2.40%)

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GM

General Motors

$35.13

0.01 (0.03%)

TSLA

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$190.80

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RNLSY

Renault

$0.00

(0.00%)

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FMC

FMC Corporation

$70.88

-0.47 (-0.66%)

, DWDP

DowDuPont

$31.10

0.16 (0.52%)

13:11
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DowDuPont spinoff a new agriculture stock, FMC safer bet, Barron's says »

The crop-protection and…

FMC

FMC Corporation

$70.88

-0.47 (-0.66%)

DWDP

DowDuPont

$31.10

0.16 (0.52%)

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  • 29

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MGM

MGM Resorts

$25.55

0.19 (0.75%)

13:03
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PYPL

PayPal

$109.82

-0.09 (-0.08%)

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$119.52

1.07 (0.90%)

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PYPL

PayPal

$109.82

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AXP

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$119.52

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MA

MasterCard

$251.40

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V

Visa

$162.72

1.2 (0.74%)

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GOOG

Alphabet

$1,132.99

-7.56 (-0.66%)

, GOOGL

Alphabet Class A

$1,138.90

-5.98 (-0.52%)

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On The Fly
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Catch up on the top…

GOOG

Alphabet

$1,132.99

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GOOGL

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-5.98 (-0.52%)

MSFT

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$126.23

0.04 (0.03%)

AMBA

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$38.28

1.07 (2.88%)

ON

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NKE

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ADDYY

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UAA

Under Armour

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UA

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FL

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VMC

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FLR

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ACM

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X

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AKS

AK Steel

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NUE

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$0.00

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FCAU

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GM

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HMC

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TM

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UBER

Uber

$41.40

0.94 (2.32%)

17:49
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Hot Stocks
Uber board director Ryan Graves intends to resign »

According to a regulatory…

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  • 30

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APTO

Aptose Biosciences

$2.01

0.03 (1.52%)

17:46
05/24/19
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17:46
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17:46
Syndicate
Aptose Biosciences files for $40M at-the-market common stock offering »

Piper Jaffray and…

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  • 04

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TRNX

Taronis Technologies

$0.48

0.004 (0.84%)

17:26
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Breaking Syndicate news story on Taronis Technologies »

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USEG

U.S. Energy

$0.45

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17:25
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Hot Stocks
U.S. Energy discloses Nasdaq notice regarding delayed 10-Q filing »

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AAPL

Apple

$179.03

-0.64 (-0.36%)

17:22
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Apple sued over allegedly selling users' iTunes data, Bloomberg says »

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  • 03

    Jun

SPCB

SuperCom

$1.17

-0.005 (-0.43%)

17:21
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SuperCom discloses Nasdaq notice regarding delayed 20-F filing »

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USEG

U.S. Energy

$0.45

0.0373 (9.10%)

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U.S. Energy receives noncompliance notice from Nasdaq »

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MYOV

Myovant Sciences

$12.39

-0.465 (-3.62%)

17:18
05/24/19
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17:18
Syndicate
Breaking Syndicate news story on Myovant Sciences »

Myovant Sciences files to…

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MYOV

Myovant Sciences

$12.39

-0.465 (-3.62%)

17:17
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Syndicate
Breaking Syndicate news story on Myovant Sciences »

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NVS

Novartis

$87.49

3.03 (3.59%)

, QGEN

Qiagen

$38.22

-0.255 (-0.66%)

16:57
05/24/19
05/24
16:57
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16:57
Hot Stocks
Qiagen launches diagnostic for PIK3CA biomarkers in breast cancer »

Qiagen (QGEN) announced…

NVS

Novartis

$87.49

3.03 (3.59%)

QGEN

Qiagen

$38.22

-0.255 (-0.66%)

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AVH

Avianca

$3.96

0.91 (29.84%)

16:56
05/24/19
05/24
16:56
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16:56
Periodicals
ANAC suspends flights, operations of Avianca Brasil, Reuters reports »

Brazil's ANAC said…

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AAPL

Apple

$179.03

-0.64 (-0.36%)

16:53
05/24/19
05/24
16:53
05/24/19
16:53
Periodicals
Apple acquires startup Tueo Health, CNBC reports »

Apple has bought Tueo…

03/08/13
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  • 03

    Jun

SHSP

SharpSpring

$16.37

-0.24 (-1.44%)

16:52
05/24/19
05/24
16:52
05/24/19
16:52
Syndicate
Breaking Syndicate news story on SharpSpring »

SharpSpring files to sell…

03/08/13
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  • 13

    Jun

CREG

China Recycling Energy

$0.48

0.005 (1.05%)

16:41
05/24/19
05/24
16:41
05/24/19
16:41
Syndicate
Breaking Syndicate news story on China Recycling Energy »

China Recycling Energy…

03/08/13
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FENC

Fennec

$3.88

(0.00%)

16:36
05/24/19
05/24
16:36
05/24/19
16:36
Conference/Events
Fennec management to meet with Wedbush »

Meeting to be held in…

03/08/13
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  • 29

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    Jun

TD

Toronto-Dominion

$56.66

0.65 (1.16%)

16:35
05/24/19
05/24
16:35
05/24/19
16:35
Syndicate
Breaking Syndicate news story on Toronto-Dominion »

Toronto-Dominion files…

03/08/13
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16:30
05/24/19
05/24
16:30
05/24/19
16:30
Options
Preliminary option volume of 15.7M today »

Preliminary option volume…

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