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TGTX

TG Therapeutics

$8.45

0.305 (3.75%)

09:18
05/07/19
05/07
09:18
05/07/19
09:18

TG Therapeutics announces long-term follow-up data from ublituximab trial

TG Therapeutics announced the presentation of long-term follow-up data from the Phase 2 and open label extension, or OLE, trial of ublituximab, the company's novel glycoengineered anti-CD20 monoclonal antibody, in relapsing forms of Multiple Sclerosis, or RMS. The data are being presented at the American Academy of Neurology. Ublituximab continues to be well tolerated, with a median duration of follow-up of 97.5 weeks. No subjects discontinued due to an adverse event, or AE, related to ublituximab on the Phase 2 or during the OLE. AEs deemed at least possibly related to ublituximab were infrequent during the OLE with all patients dosed 450mg of ublituximab administered in a one-hour infusion. Infusion related reactions, or IRRs, were rare during the OLE, occurring in only 4 patients, all Grade 1 or 2. These long-term safety data, and the Phase 2 efficacy data support the ongoing, fully enrolled, international Phase 3 program evaluating ublituximab for the treatment of RMS. The Phase 3 trials, entitled ULTIMATE I and ULTIMATE II, are being conducted under special protocol assessment, or SPA, agreement with the FDA.

TGTX TG Therapeutics
$8.45

0.305 (3.75%)

04/12/19
HCWC
04/12/19
NO CHANGE
Target $20
HCWC
Buy
TG granted orphan status for three lymphoma indications, says H.C. Wainwright
The FDA granted TG Therapeutics' umbralisib orphan drug status for three lymphoma indications, H.C. Wainwright analyst Edward White tells investors in a research note. The analyst continues to believe umbralisib will be launched in 2021, generating sales of $10.6M, growing to $141.5M in 2027. He keeps a Buy rating on TG Therapeutics with a $20 price target.
03/29/19
CANT
03/29/19
INITIATION
Target $17
CANT
Overweight
Cantor starts TG Therapeutics with Overweight rating, $17 price target
Cantor Fitzgerald analyst Alethia Young initiated coverage of TG Therapeutics with an Overweight rating and $17 price target. The analyst believes umbralisib and ublituximab have attractive profiles in oncology and autoimmune B-cell diseases. Investors are cautious on the PI3K commercial potential and give no credit to multiple sclerosis due to the competitive yet price sensitive landscape, but both lead assets as clinically de-risked with proven targets, Young tells investors in a research note. She thinks the risk/reward on TG shares is positive.
03/29/19
CANT
03/29/19
INITIATION
Target $17
CANT
Overweight
TG Therapeutics initiated with an Overweight at Cantor Fitzgerald
Cantor Fitzgerald analyst Alethia Young initiated TG Therapeutics with an Overweight and $17 price target.
03/05/19
RHCO
03/05/19
NO CHANGE
Target $15
RHCO
Buy
TG Therapeutics price target lowered to $15 from $24 at SunTrust
SunTrust analyst Peter Lawson lowered his price target on TG Therapeutics to $15, saying he has updated his model on the company's Marginal zone lymphoma readouts and the Follicular lymphoma data with new timing estimates for catalysts in those programs. The analyst also keeps his Buy rating on the shares longer term, saying he remains positive on TG Therapeutics' "capital-efficient strategy of utilizing therapeutics to develop novel combination therapies" and sees its proprietary doublet TG-1101 + TGR-1202 potentially serving patients across all lines of Chronic Lymphocytic Leukemia.

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