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PRTA

Prothena

$10.35

-0.21 (-1.99%)

16:16
05/07/19
05/07
16:16
05/07/19
16:16

Prothena reports Q EPS (52c), consensus (62c)

Reports Q2 revenue $186K, consensus $160K. "We continue to advance our neuroscience pipeline of investigational therapies, and are progressing several programs towards key milestones," said Gene Kinney, Ph.D., President and Chief Executive Officer of Prothena. "We have initiated cell line development of a lead candidate for our tau program under our collaboration with Celgene. Enrollment in our Phase 1 study of PRX004 in ATTR amyloidosis is progressing and we now anticipate that the fourth quarter update on this program will include data from cohorts 1 through 4. Data from Part 1 of the Phase 2 PASADENA study of prasinezumab in Parkinson's disease, which is being run by Roche, are expected in 2020. We also recently reported results from the Phase 3 VITAL study of NEOD001 in AL amyloidosis and are exploring business development opportunities that could result in further clinical investigation of NEOD001." The Company is updating its full year 2019 net cash burn from operating and investing activities, and expects it to be $57-65 million, representing a decrease of approximately $7 million, and expects to end the year with approximately $371 million in cash, cash equivalents and restricted cash (midpoint). The Company had planned on initiating cell line development of a lead candidate for an Amyloid beta discovery program this year but will not be making additional investments in this program at this time based on the recent discontinuation of Biogen's aducanumab program. The updated estimated full year 2019 cash burn from operating and investing activities is primarily driven by an updated estimated net loss of $83-94 million, which includes an estimated $24 million of non-cash shared-based compensation expense.

PRTA Prothena
$10.35

-0.21 (-1.99%)

05/21/18
LEHM
05/21/18
DOWNGRADE
Target $12
LEHM
Underweight
Prothena downgraded to Underweight from Equal Weight at Barclays
Barclays analyst Geoffrey Meacham downgraded Prothena to Underweight and cut his price target for the shares to $12 from $14. The analyst sees limited value creating pipeline events in the near-term after the company discontinued development of NEOD001, an investigational antibody that was being evaluated for the treatment of AL amyloidosis. He believes it remains too early to assign much value to PRX002 in Parkinson's or PRX004 in ATTR amyloidosis.
06/15/18
CANT
06/15/18
NO CHANGE
Target $18
CANT
Overweight
Prothena price target raised to $18 from $14 at Cantor Fitzgerald
Cantor Fitzgerald analyst William Tanner raised his price target for Prothena to $18 citing his analysis of the potential value of the company's drug discovery platform and management's recently announced restructuring plan. The analyst reiterates a Overweight rating on the shares.
03/04/19
CANT
03/04/19
INITIATION
Target $20
CANT
Overweight
Prothena assumed with an Overweight at Cantor Fitzgerald
Cantor Fitzgerald analyst Charles Duncan assumed coverage of Prothena with an Overweight rating and raised his price target for the shares to $20 from $18. Prothena's lead candidate prasinezumab for the treatment of Parkinson's disease is a potential first-in-class anti-alpha-synuclein antibody, targeting an evidence-based mechanism of disease pathology, Duncan tells investors in a research note.

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