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NCNA

NuCana

$14.53

-0.17 (-1.16%)

16:13
05/14/19
05/14
16:13
05/14/19
16:13

NuCana reports Q1 EPS GBP (.17) versus GBP (.20) last year

It has been a good start to the year and we are pleased with NuCana's continued progress," said Hugh S. Griffith, NuCana's Founder and Chief Executive Officer. "In February 2019, we announced two abstracts related to NUC-3373 that were selected for presentation at the American Association for Cancer Research Annual Meeting 2019 in April. NUC-3373 is NuCana's second ProTide in clinical development and is a transformation of the active anti-cancer metabolite of 5-fluorouracil, one of the most widely prescribed anti-cancer agents. Our current findings have shown that NUC-3373 has an additional mechanism of action for promoting anti-cancer activity that is independent of the DNA damage pathway. NUC-3373 inhibits the target enzyme, thymidylate synthase, causing nuclear to cytoplasmic translocation and induction of endoplasmic reticulum stress. We look forward to announcing additional data in 2019 from the ongoing Phase I study of NUC-3373, as well as data from the ongoing Phase 1b study of NUC-3373 in combination with other agents typically combined with 5-FU."

NCNA NuCana
$14.53

-0.17 (-1.16%)

10/18/18
PIPR
10/18/18
INITIATION
Target $36
PIPR
Overweight
NuCana initiated with an Overweight at Piper Jaffray
Piper Jaffray analyst Joseph Catanzaro started NuCana with an Overweight rating and $36 price target, stating that data for its lead product, Acelarin, have "strongly" pointed towards platform validation. He sees an opportunity for the drug in platinum-resistant ovarian cancer and sees the potential for it to "establish a new frontline standard of care in biliary tract cancer," Catanzaro tells investors.
10/21/18
PIPR
10/21/18
NO CHANGE
Target $36
PIPR
Overweight
NuCana updated Phase Ib data positive for acelarin in biliary cancer, says Piper Jaffray
Piper Jaffray analyst Joseph Catanzaro notes that NuCana presented updated Phase Ib data for Acelarin plus cisplatin in 1st-line advanced BTC at ESMO this weekend. An ORR of 50% in 14 patients is consistent with the abstract and continues to suggest a near doubling of standard of care, he adds, highlighting that tumor reductions appear to be durable out to the 36-week assessment and the safety profile is unremarkable compared to gem/cis. The analyst maintains his positive outlook for the planned Phase III trial and the opportunity to establish a new standard of care for this sizable patient population. Catanzaro reiterates an Overweight rating and $36 price target on the shares.
03/10/19
PIPR
03/10/19
NO CHANGE
Target $35
PIPR
Overweight
NuCana shares 'significantly undervalued,' says Piper Jaffray
Piper Jaffray analyst Joseph Catanzaro is "incrementally more positive" around NuCana's "ambitious" development strategy for the ProTide platform after speaking to management. The analyst continues to believe that clinical data presented to date have fully supported ProTide's mechanism of action. Shares of NuCana are "significantly undervalued for the clear blockbuster potential" of NuCana's two lead assets, Catanzaro tells investors in a research note. He maintains an Overweight rating on the shares and trimmed his price target to $35 from $36.

TODAY'S FREE FLY STORIES

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DDAIF

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$0.00

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FCAU

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F

Ford

$9.83

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GM

General Motors

$35.13

0.01 (0.03%)

HMC

Honda

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UBER

Uber

$41.40

0.94 (2.32%)

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APTO

Aptose Biosciences

$2.01

0.03 (1.52%)

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TRNX

Taronis Technologies

$0.48

0.004 (0.84%)

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USEG

U.S. Energy

$0.45

0.0373 (9.10%)

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AAPL

Apple

$179.03

-0.64 (-0.36%)

17:22
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SPCB

SuperCom

$1.17

-0.005 (-0.43%)

17:21
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USEG

U.S. Energy

$0.45

0.0373 (9.10%)

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MYOV

Myovant Sciences

$12.39

-0.465 (-3.62%)

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MYOV

Myovant Sciences

$12.39

-0.465 (-3.62%)

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NVS

Novartis

$87.49

3.03 (3.59%)

, QGEN

Qiagen

$38.22

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QGEN

Qiagen

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AVH

Avianca

$3.96

0.91 (29.84%)

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AAPL

Apple

$179.03

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SHSP

SharpSpring

$16.37

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CREG

China Recycling Energy

$0.48

0.005 (1.05%)

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FENC

Fennec

$3.88

(0.00%)

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TD

Toronto-Dominion

$56.66

0.65 (1.16%)

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CBUS

Cibus

$0.00

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BA

Boeing

$355.14

4.57 (1.30%)

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FB

Facebook

$181.03

0.14 (0.08%)

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$355.14

4.57 (1.30%)

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FB

Facebook

$181.03

0.14 (0.08%)

BA

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$355.14

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UAL

United Continental

$80.77

-0.14 (-0.17%)

SMI

SMIC

$5.23

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HPQ

HP Inc.

$20.03

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HPE

HP Enterprise

$14.36

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NVS

Novartis

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CNC

Centene

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WCG

WellCare

$275.45

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TSS

TSYS

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GPN

Global Payments

$153.42

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HIBB

Hibbett Sports

$23.91

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DVAX

Dynavax

$5.77

-0.59 (-9.28%)

FL

Foot Locker

$44.39

-8.455 (-16.00%)

SPLK

Splunk

$119.13

-9.55 (-7.42%)

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VIX

Volatility Index S&P 500 Options

$0.00

(0.00%)

16:20
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$NSD

NASDAQ Market Internals

$0.00

(0.00%)

16:17
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NASDAQ market internals summary »

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$NYE

NYSE Market Internals

$0.00

(0.00%)

16:16
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05/24
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16:16
Technical Analysis
NYSE market internals summary »

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RHE

Regional Health Properties

$2.06

0.09 (4.57%)

16:15
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