Breaking News Instant updates and real-time market news.

PRNB

Principia Biopharma

$31.99 /

+0.76 (+2.43%)

08:06
05/20/19
05/20
08:06
05/20/19
08:06

Principia Biopharma presents PRN1371 data at AACR meeting

Principia Biopharma announced data from its Phase 1, multicenter, dose-escalation clinical trial of PRN1371, an irreversible covalent FGFR1-4 kinase inhibitor, in patients with advanced solid tumors. The poster was presented at the AACR Bladder Cancer meeting. PRN1371 is a covalent, highly selective FGFR1-4 inhibitor, which targets a cysteine residue within the kinase domain. This approach has the potential to enable selective and sustained inhibition of FGFR without the need to maintain high systemic exposure of the drug. The Phase 1, open-label dose escalation portion of the PRN1371 trial in adult patients with advanced solid tumors has been completed in 36 patients. PRN1371 was well tolerated and two patients continued on study. While the trial was not designed to assess efficacy, stable disease after two 28-day treatment cycles was observed in 11 out of 36 patients. The most common treatment related adverse event was hyperphosphatemia, a known side effect of FGFR inhibitors. A cohort expansion portion of the study has been initiated in metastatic urothelial carcinoma patients with identified FGFR genetic alterations at a dose of 35 mg once daily and is currently ongoing.

  • 11

    Jun

PRNB Principia Biopharma
$31.99 /

+0.76 (+2.43%)

04/17/19
Fly Intel: Top five analyst initiations
04/16/19 Stifel
Stifel starts Principia at Buy ahead of 'catalyst rich' Q4
04/16/19 Stifel
Principia Biopharma initiated with a Buy at Stifel
10/09/18 Baird
Principia Biopharma initiated with an Outperform at Baird

TODAY'S FREE FLY STORIES

Recommendations
Kornit Digital selloff brings attractive entry point, says Stifel » 06:43
02/28/20
02/28
06:43
02/28/20
06:43
KRNT

Kornit Digital

$38.57 /

-2.77 (-6.70%)

Stifel analyst Patrick Ho…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Recommendations
Farfetch price target lowered to $17 from $20 at KeyBanc » 06:43
02/28/20
02/28
06:43
02/28/20
06:43
FTCH

Farfetch

$9.54 /

-0.33 (-3.35%)

KeyBanc analyst Edward…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Conference/Events
eBay management to meet with UBS » 06:43
02/28/20
02/28
06:43
02/28/20
06:43
EBAY

eBay

$34.87 /

-1.68 (-4.60%)

Meeting to be held in New…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Digital Realty increases quarterly dividend 4% to $1.12 per share » 06:42
02/28/20
02/28
06:42
02/28/20
06:42
DLR

Digital Realty

$123.03 /

-7.37 (-5.65%)

Digital Realty announced…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Recommendations
Wells Fargo cuts large-cap bank estimates, but notes balance sheet strength » 06:41
02/28/20
02/28
06:41
02/28/20
06:41
MTB

M&T Bank

/

+

, C

Citi

$64.44 /

-3.72 (-5.46%)

, FITB

Fifth Third

$25.20 /

-1.45 (-5.44%)

, JPM

JPMorgan

$121.38 /

-5.22 (-4.12%)

, KEY

KeyCorp

$16.71 /

-0.97 (-5.49%)

, MS

Morgan Stanley

$45.43 /

-1.8 (-3.81%)

, GS

Goldman Sachs

$204.33 /

-10.16 (-4.74%)

, USB

U.S. Bancorp

$47.50 /

-2.15 (-4.33%)

, PNC

PNC Financial

$130.65 /

-8.1 (-5.84%)

, RF

Regions Financial

$13.85 /

-0.725 (-4.97%)

, CMA

Comerica

$53.25 /

-2.5 (-4.48%)

, BAC

Bank of America

$29.12 /

-1.495 (-4.88%)

, ZION

Zions Bancorp

$40.61 /

-1.23 (-2.94%)

Wells Fargo analyst Mike…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Recommendations
AutoZone price target lowered to $1,325 from $1,425 at UBS » 06:41
02/28/20
02/28
06:41
02/28/20
06:41
AZO

AutoZone

$1,010.24 /

-3.73 (-0.37%)

UBS analyst Michael…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Recommendations
Entegris pullback brings attractive entry point, says Stifel » 06:39
02/28/20
02/28
06:39
02/28/20
06:39
ENTG

Entegris

$51.54 /

-1.41 (-2.66%)

Stifel analyst Patrick Ho…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Vistra Energy reports Q4 adjusted EBITDA from ongoing operations of $775M  06:39
02/28/20
02/28
06:39
02/28/20
06:39
VST

Vistra Energy

$20.59 /

-1.08 (-4.98%)

 
ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Earnings
PNM Resources backs FY20 EPS view of $2.16-$2.26, consensus $2.22  06:39
02/28/20
02/28
06:39
02/28/20
06:39
PNM

PNM Resources

$49.77 /

-2.49 (-4.76%)

 
ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Earnings
PNM Resources reports Q4 EPS 36c, consensus 33c » 06:38
02/28/20
02/28
06:38
02/28/20
06:38
PNM

PNM Resources

$49.77 /

-2.49 (-4.76%)

"Financial results…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Upgrade
Heico upgraded to Neutral from Sell at UBS » 06:37
02/28/20
02/28
06:37
02/28/20
06:37
HEI

Heico

$105.26 /

+1.81 (+1.75%)

UBS analyst Louis…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Recommendations
Whiting Petroleum price target lowered to $2 from $7 at Ladenburg » 06:37
02/28/20
02/28
06:37
02/28/20
06:37
WLL

Whiting Petroleum

$1.71 /

-0.555 (-24.56%)

Ladenburg Thalmann…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
DPW Holdings unit terminates agreement to buy two broker-dealers » 06:35
02/28/20
02/28
06:35
02/28/20
06:35
DPW

DPW Holdings

$1.19 /

-0.165 (-12.22%)

DPW Holdings announced on…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

Earnings
Magellan Health sees FY20 adjusted EPS $3.34-$4.14, consensus $4.70 » 06:33
02/28/20
02/28
06:33
02/28/20
06:33
MGLN

Magellan Health

$65.73 /

-1.41 (-2.10%)

Sees FY20 revenue…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Recommendations
BioMarin price target raised to $105 from $95 at Citi » 06:33
02/28/20
02/28
06:33
02/28/20
06:33
BMRN

BioMarin

$89.86 /

-1.54 (-1.68%)

Citi analyst Mohit Bansal…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Earnings
Magellan Health reports Q4 adjusted EPS $1.24, consensus 97c » 06:32
02/28/20
02/28
06:32
02/28/20
06:32
MGLN

Magellan Health

$65.73 /

-1.41 (-2.10%)

Reports Q4 revenue $1.8B,…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Recommendations
Regeneron price target raised to $540 from $420 at Citi » 06:31
02/28/20
02/28
06:31
02/28/20
06:31
REGN

Regeneron

$431.28 /

-26.97 (-5.89%)

Citi analyst Mohit Bansal…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Earnings
Strategic Education reports Q4 adjusted EPS $2.13, consensus $1.43 » 06:31
02/28/20
02/28
06:31
02/28/20
06:31
STRA

Strategic Education

$145.79 /

-5.06 (-3.35%)

Reports Q4 revenue…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Takeda Pharmaceutical gets positive CHMP opinion for SC vedolizumab » 06:28
02/28/20
02/28
06:28
02/28/20
06:28
TAK

Takeda Pharmaceutical

$17.62 /

-0.62 (-3.40%)

Takeda Pharmaceutical…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Occidental Petroleum sees FY20 total company production 1,360-1,390 Mboed » 06:28
02/28/20
02/28
06:28
02/28/20
06:28
OXY

Occidental Petroleum

$31.80 /

-2.4 (-7.02%)

Sees FY20 Permian…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Upgrade
NiSource upgraded to Outperform from Neutral at Credit Suisse » 06:27
02/28/20
02/28
06:27
02/28/20
06:27
NI

NiSource

$27.33 /

-0.46 (-1.66%)

Credit Suisse analyst…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Occidental Petroleum sees Q1 production 1,375-1,395 Mboed » 06:27
02/28/20
02/28
06:27
02/28/20
06:27
OXY

Occidental Petroleum

$31.80 /

-2.4 (-7.02%)

Sees Q1 Permian resources…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Hot Stocks
Occidental Petroleum 'on track' to meet or exceed $1.2B in annualized synergies » 06:26
02/28/20
02/28
06:26
02/28/20
06:26
OXY

Occidental Petroleum

$31.80 /

-2.4 (-7.02%)

Says on track to meet or…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Upgrade
RBS upgraded to Neutral from Underperform at BofA » 06:25
02/28/20
02/28
06:25
02/28/20
06:25
RBS

RBS

$4.68 /

-0.235 (-4.78%)

BofA upgraded Royal Bank…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return tomorrow

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Periodicals
Coronavirus seen prolonging U.S. freight slump, WSJ says » 06:25
02/28/20
02/28
06:25
02/28/20
06:25
UPS

UPS

$90.19 /

-3.58 (-3.82%)

, FDX

FedEx

$138.99 /

-5.56 (-3.85%)

, CSX

CSX

$72.36 /

-2.7 (-3.60%)

The continuing slump in…

Story temporarily locked.
To read stories as they happen please subscribe, Login above, or return in 9 minutes

Get Free Trial

ShowHide Related Items >><<
03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.