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MRK

Merck

$78.86

0.15 (0.19%)

16:34
05/20/19
05/20
16:34
05/20/19
16:34

Merck announces Phase 3 KEYNOTE-119 trial does not meet OS primary endpoint

Merck announced that the Phase 3 KEYNOTE-119 trial evaluating Keytruda, Merck's anti-PD-1 therapy, as monotherapy for the second- or third-line treatment of patients with metastatic triple-negative breast cancer, or TNBC, did not meet its pre-specified primary endpoint of superior overall survival, or OS, compared to chemotherapy. Other endpoints were not formally tested per the study protocol because the primary endpoint of OS was not met. The safety profile of KEeytruda in this trial was consistent with that observed in previously reported studies involving patients treated with Keytruda monotherapy; no new safety concerns were identified. Results will be presented at an upcoming medical meeting. The Keytruda breast cancer clinical development program encompasses several internal and external collaborative studies, including three ongoing registration-enabling studies in TNBC.

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MRK Merck
$78.86

0.15 (0.19%)

05/13/19
ATLE
05/13/19
UPGRADE
ATLE
Overweight
Merck upgraded to Overweight from Neutral at Atlantic Equities
05/13/19
05/13/19
UPGRADE

Fly Intel: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Royal Dutch Shell (RDS.A, RDS.B) upgraded to Buy from Hold at Deutsche Bank and HSBC. 2. KB Home (KBH) upgraded to Overweight from Equal Weight at Barclays with analyst Matthew Bouley saying his firm's spring agent survey confirmed that housing fundamentals have improved and stabilized. 3. Becton Dickinson (BDX) upgraded to Overweight from Equal Weight at Barclays with analyst Kristen Stewart saying the pullback in the shares since the FDA update on drug-coated balloons on March 15, coupled with the resetting of expectations following the company's Q2 results, provides an opportunity for investors. 4. Merck (MRK) upgraded to Overweight from Neutral at Atlantic Equities. 5. Bausch Health (BHC) upgraded to Neutral from Underweight at JPMorgan with analyst Chris Schott saying while a number of challenges remain in the story given the company's high leverage and controversial Xifaxan loss of exclusivity, its EBITDA is "clearly stabilizing and should begin to grow from here." This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
05/14/19
HCWC
05/14/19
NO CHANGE
HCWC
BioLineRx has multiple catalysts coming in 2019, says H.C. Wainwright
H.C. Wainwright analyst Joseph Pantginis reiterated a Buy rating and $3 price target on BioLineRx (BLRX) after the company reported in-line Q1 results, with the analyst seeing BL-8040 continuing to deliver positive data on multiple clinical fronts. Pantginis sees "multiple catalysts across all the ongoing programs" for BioLineRx in 2019 that could end the continuing suffering of the shares, including top-line results in the second half of the year from the "Phase 2 triple combo pancreatic cancer trial of BL-8040, Keytruda and chemotherapy under the company's collaboration with Merck (MRK)."
05/16/19
JEFF
05/16/19
NO CHANGE
Target $29
JEFF
Buy
Jefferies calls Iovance 'big winner' at ASCO, sees up to 40% share rally
Jefferies analyst Biren Amin calls the data reported by Iovance Biotherapeutics (IOVA) the "big winner" for the American Society of Clinical Oncology annual meeting. The ASCO update suggests Iovance's tumor infiltrating lymphocytes therapy could open the door for cell therapy in the "lucrative" solid-tumor market, Amin tells investors in a research note. He points out the company reported that no new patients have progressed in the melanoma trial and offered first evidence of clinically meaningful durability for TIL therapy. Also, its cervical data that reported a 44% overall response rate is three-times greater than reported with Merck's (MRK) Keytruda in a similar patient population, contends Amin. He believes last night's update could drive a 30%-40% rally in shares of Iovance. The analyst keeps a Buy rating on the name with a $29 price target. Iovance in premarket trading is up 26%, or $2.97, to $14.20.

TODAY'S FREE FLY STORIES

BDX

Becton Dickinson

$245.32

7.2 (3.02%)

17:55
06/20/19
06/20
17:55
06/20/19
17:55
Hot Stocks
Becton Dickinson backs safety of its Lutonix drug-coated balloons in SFA »

BD issued the following…

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  • 20

    Jun

CPF

Central Pacific

$28.49

-0.13 (-0.45%)

17:41
06/20/19
06/20
17:41
06/20/19
17:41
Hot Stocks
Central Pacific authorizes buyback of up to $30M in common stock »

Central Pacific announced…

03/08/13
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    Nov

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AEL

American Equity

$27.51

0.3 (1.10%)

17:33
06/20/19
06/20
17:33
06/20/19
17:33
Hot Stocks
American Equity director Debra Richardson sells almost $2.2M in company shares »

American Equity director…

03/08/13
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03/06/13
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03/06/13
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SEE

Sealed Air

$43.68

-0.13 (-0.30%)

17:28
06/20/19
06/20
17:28
06/20/19
17:28
Earnings
Sealed Air backs FY19 adjusted EPS view $2.65-$2.75, consensus $2.73 »

Sealed Air continues to…

03/08/13
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03/06/13
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03/06/13
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SEE

Sealed Air

$43.68

-0.13 (-0.30%)

17:27
06/20/19
06/20
17:27
06/20/19
17:27
Hot Stocks
Sealed Air names James Sullivan as new CFO, effective June 24 »

Sealed Air announced it…

03/08/13
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03/08/13
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AJRD

Aerojet Rocketdyne

$43.01

1.49 (3.59%)

17:27
06/20/19
06/20
17:27
06/20/19
17:27
Hot Stocks
Aerojet Rocketdyne subsidiary awarded $140.18M missile defense modification »

Coleman Aerospace, a…

03/08/13
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03/08/13
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03/06/13
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03/06/13
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SEE

Sealed Air

$43.68

-0.13 (-0.30%)

17:25
06/20/19
06/20
17:25
06/20/19
17:25
Hot Stocks
Sealed Air terminates CFO William Stiehl for cause, effective immediately »

Sealed Air announced that…

03/08/13
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03/06/13
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03/06/13
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BBU

Brookfield Business Partners

$41.25

1.28 (3.20%)

, BAM

Brookfield

$48.38

0.29 (0.60%)

17:15
06/20/19
06/20
17:15
06/20/19
17:15
Syndicate
Brookfield Business Partners announces $795M equity offering »

Brookfield Business…

BBU

Brookfield Business Partners

$41.25

1.28 (3.20%)

BAM

Brookfield

$48.38

0.29 (0.60%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
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  • 08

    Aug

AXLA

Axcella

$10.39

0.27 (2.67%)

17:13
06/20/19
06/20
17:13
06/20/19
17:13
Earnings
Axcella reports Q1 EPS ($2.43), consensus (49c) »

Q1 operating expenses…

03/08/13
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03/08/13
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03/06/13
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LKSD

LSC Communications

$5.83

0.07 (1.22%)

17:11
06/20/19
06/20
17:11
06/20/19
17:11
Hot Stocks
LSC comments on DOJ action regarding proposed transaction with Quad »

LSC Communications…

03/08/13
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03/08/13
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03/06/13
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03/06/13
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QUAD

Quad/Graphics

$9.75

0.09 (0.93%)

, LKSD

LSC Communications

$5.83

0.07 (1.22%)

17:10
06/20/19
06/20
17:10
06/20/19
17:10
Hot Stocks
Quad/Graphics intends to defend proposed LSC Communications acquisition »

Quad/Graphics (QUAD)…

QUAD

Quad/Graphics

$9.75

0.09 (0.93%)

LKSD

LSC Communications

$5.83

0.07 (1.22%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
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SFM

Sprouts Farmers Market

$19.52

0.14 (0.72%)

17:04
06/20/19
06/20
17:04
06/20/19
17:04
Hot Stocks
Sprouts Farmers Market interim co-CEO/CFO Brad Lukow resigns »

Sprouts Farmers Market…

03/08/13
Wedge Partners
03/08/13
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03/06/13
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03/06/13
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  • 13

    Nov

NAKD

Naked Brand Group

$0.27

0.0025 (0.93%)

17:03
06/20/19
06/20
17:03
06/20/19
17:03
Syndicate
Breaking Syndicate news story on Naked Brand Group »

Naked Brand Group files…

03/08/13
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03/08/13
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03/06/13
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03/06/13
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HPQ

HP Inc.

$20.85

0.22 (1.07%)

16:57
06/20/19
06/20
16:57
06/20/19
16:57
Hot Stocks
HP Inc. General Counsel sells 20K shares of common stock »

In a regulatory filing,…

03/08/13
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03/06/13
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03/06/13
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CPT

Camden Property

$107.61

0.57 (0.53%)

16:54
06/20/19
06/20
16:54
06/20/19
16:54
Hot Stocks
Camden Property COO sells 16.2K shares of common stock »

In a regulatory filing,…

03/08/13
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03/08/13
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03/06/13
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03/06/13
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COMM

CommScope

$16.00

0.38 (2.43%)

16:52
06/20/19
06/20
16:52
06/20/19
16:52
Hot Stocks
CommScope's distributed antenna system patents upheld in favorable ruling »

CommScope received…

03/08/13
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  • 21

    Jun

INVH

Invitation Homes

$27.68

-0.07 (-0.25%)

16:50
06/20/19
06/20
16:50
06/20/19
16:50
Syndicate
Invitation Homes announces offering of 37.5M shares of common stock for holders »

Invitation Homes…

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EGY

VAALCO Energy

$1.55

0.03 (1.97%)

16:46
06/20/19
06/20
16:46
06/20/19
16:46
Hot Stocks
VAALCO Energy announces $10M stock buyback program »

VAALCO Energy announced…

03/08/13
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ENTG

Entegris

$38.50

1.36 (3.66%)

, INTC

Intel

$47.16

0.08 (0.17%)

16:45
06/20/19
06/20
16:45
06/20/19
16:45
Initiation
Entegris, Intel, TSMC initiated  »

Entegris initiated with a…

ENTG

Entegris

$38.50

1.36 (3.66%)

INTC

Intel

$47.16

0.08 (0.17%)

TSM

TSMC

$40.52

1.11 (2.82%)

03/08/13
Wedge Partners
03/08/13
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03/06/13
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03/06/13
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  • 09

    Jul

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    Jul

16:38
06/20/19
06/20
16:38
06/20/19
16:38
General news
Money Supply M2 Weekly Change data reported »

Week of 6/10 Money Supply…

LH

LabCorp

$168.01

-1.54 (-0.91%)

16:37
06/20/19
06/20
16:37
06/20/19
16:37
Upgrade
LabCorp rating change at Deutsche Bank »

LabCorp upgraded to Buy…

03/08/13
Wedge Partners
03/08/13
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03/06/13
Citigroup
03/06/13
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  • 20

    Jun

FNKO

Funko

$24.25

2.02 (9.09%)

16:35
06/20/19
06/20
16:35
06/20/19
16:35
Initiation
Funko initiated  »

Funko initiated with a…

03/08/13
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03/08/13
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03/06/13
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03/06/13
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  • 25

    Jun

HSIC

Henry Schein

$70.96

-1.06 (-1.47%)

16:35
06/20/19
06/20
16:35
06/20/19
16:35
Hot Stocks
Henry Schein CFO Steven Paladino sells almost $1.5M in company shares »

Henry Schein CFO Steven…

03/08/13
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03/08/13
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03/06/13
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03/06/13
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16:34
06/20/19
06/20
16:34
06/20/19
16:34
General news
Fed Balance Sheet Level data reported »

Week of 6/19 Fed Balance…

CTRV

ContraVir Pharmaceuticals

$4.27

-0.485 (-10.21%)

16:34
06/20/19
06/20
16:34
06/20/19
16:34
Hot Stocks
ContraVir Pharma receives positive FDA response to NASH candidate plans »

ContraVir Pharmaceuticals…

03/08/13
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03/08/13
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03/06/13
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03/06/13
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