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RLMD

Relmada Therapeutics

$0.00

(0.00%)

08:05
05/31/19
05/31
08:05
05/31/19
08:05

Relmada Therapeutics presents development program of REL1017

Relmada Therapeutics announced that a review of the company progress in the development of REL1017 for the treatment of depression and other CNS disorders was presented this week during the 2019 American Society of Clinical Psychopharmacology meeting in Scottsdale, AZ. The poster presentation entitled, "Development of the N-Methyl-D-Aspartate Receptor (NMDAR) Antagonist d-Methadone for the Treatment of Depression and Other CNS Disorders", reported previously announced results from multiple pre-clinical studies comparing the effects of d-methadone and ketamine in different behavioral animal models used to assess antidepressant activity. Results showed that d-methadone produced improvements similar to ketamine across a range of key tests, including Forced Swim Test, Female Urine Sniffing Test, Novelty Suppressed Feeding Test, and a Chronic Unpredictable Stress protocol. In addition, d-methadone increased the expression of synaptic proteins and receptors critically involved in synaptic plasticity. The poster presentation also highlighted results from two phase 1 studies showing that d-methadone exhibited a linear pharmacokinetic profile for a range of single dose and multiple dose parameters with no serious adverse events reported. Treatment with d-methadone was also shown to have a pharmacodynamic effect on levels of brain-derived neurotrophic factor plasma, with six of the six subjects in the treatment arm demonstrating statistically significant increases in BDNF levels, while levels remained unchanged for the two patients in the placebo arm.

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OSTK

Overstock.com

$13.54

2.765 (25.66%)

09:03
06/27/19
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YEXT

Yext

$18.98

-0.36 (-1.86%)

09:03
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Yext and Hootsuite launch platform integration for customer reviews »

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  • 10

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YEXT

Yext

$18.98

-0.36 (-1.86%)

09:03
06/27/19
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Yext and Hootsuite launch platform integration for customer reviews »

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F

Ford

$9.90

0.06 (0.61%)

09:01
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VBLT

VBL Therapeutics

$1.17

-0.01 (-0.85%)

09:01
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Initiation
VBL Therapeutics initiated  »

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OVID

Ovid Therapeutics

$1.79

-0.04 (-2.19%)

09:01
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OVID

Ovid Therapeutics

$1.79

-0.04 (-2.19%)

09:00
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General news
Treasury Action: the markets were little changed on the data »

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Conference/Events
Senate Banking, Housing & Urban Affairs Committee to hold a hearing »

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OVID

Ovid Therapeutics

$1.79

-0.04 (-2.19%)

08:59
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AMC

AMC Entertainment

$9.45

-0.03 (-0.32%)

08:59
06/27/19
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Recommendations
AMC Entertainment analyst commentary  »

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INFI

Infinity Pharmaceuticals

$1.68

0.01 (0.60%)

08:58
06/27/19
06/27
08:58
06/27/19
08:58
Initiation
Infinity Pharmaceuticals initiated  »

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WAGE

WageWorks

$51.65

0.91 (1.79%)

, HQY

HealthEquity

$62.16

-2.5 (-3.87%)

08:58
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Hot Stocks
Fly Intel: Pre-market Movers »

UP AFTER EARNINGS:…

WAGE

WageWorks

$51.65

0.91 (1.79%)

HQY

HealthEquity

$62.16

-2.5 (-3.87%)

WBA

Walgreens Boots Alliance

$52.40

-0.59 (-1.11%)

KBH

KB Home

$23.58

-0.24 (-1.01%)

OFG

OFG Bancorp

$20.68

0.305 (1.50%)

NVAX

Novavax

$5.52

-0.08 (-1.43%)

CAG

Conagra Brands

$28.94

0.035 (0.12%)

MKC

McCormick

$150.58

-2.545 (-1.66%)

PDCO

Patterson Companies

$24.90

0.7 (2.89%)

PIR

Pier 1 Imports

$8.80

0.14 (1.62%)

RAD

Rite Aid

$7.11

0.26 (3.80%)

03/08/13
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  • 27

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  • 28

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  • 17

    Jul

08:58
06/27/19
06/27
08:58
06/27/19
08:58
Conference/Events
Jefferies to hold a summit »

Private Company Frac Sand…

08:56
06/27/19
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Conference/Events
JMP Securities to hold a forum »

Boston Real Estate 1:1…

08:55
06/27/19
06/27
08:55
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Conference/Events
Deutsche Bank to hold a conference »

Quarterly Healthcare…

ORIT

Oritani Financial

$16.53

0.3 (1.85%)

, VLY

Valley National

$10.12

-0.065 (-0.64%)

08:55
06/27/19
06/27
08:55
06/27/19
08:55
Upgrade
Oritani Financial, Valley National rating change  »

Oritani Financial…

ORIT

Oritani Financial

$16.53

0.3 (1.85%)

VLY

Valley National

$10.12

-0.065 (-0.64%)

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MU

Micron

$37.05

4.34 (13.27%)

, TSLA

Tesla

$219.22

-0.47 (-0.21%)

08:55
06/27/19
06/27
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08:55
Options
Notable open interest changes for June 27th »

Wednesday's total…

MU

Micron

$37.05

4.34 (13.27%)

TSLA

Tesla

$219.22

-0.47 (-0.21%)

AAPL

Apple

$199.79

4.18 (2.14%)

T

AT&T

$32.53

-0.02 (-0.06%)

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  • 09

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ASV

ASV Holdings

$1.64

-0.11 (-6.29%)

08:55
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Hot Stocks
Breaking Hot Stocks news story on ASV Holdings »

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08:55
06/27/19
06/27
08:55
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08:55
Conference/Events
Oppenheimer to hold a summit »

Summit for Emerging…

ACRS

Aclaris Therapeutics

$4.45

0.06 (1.37%)

08:54
06/27/19
06/27
08:54
06/27/19
08:54
Recommendations
Aclaris Therapeutics analyst commentary  »

Aclaris trading near cash…

03/08/13
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08:53
06/27/19
06/27
08:53
06/27/19
08:53
Conference/Events
JMP Securities to hold a tour »

Biotech Bus Tour travels…

ATHM

Autohome

$85.09

3.255 (3.98%)

08:53
06/27/19
06/27
08:53
06/27/19
08:53
Initiation
Autohome initiated  »

Bernstein bullish on…

03/08/13
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08:53
06/27/19
06/27
08:53
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08:53
Conference/Events
Deutsche Bank to hold a conference »

Asia Internet Corporate…

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