Compugen presents update on COM701 Phase 1 trial at ASCO
Compugen announced that its ongoing Phase 1 clinical trial evaluating COM701, a first-in-class therapeutic antibody targeting PVRIG, was featured in a trial-in-progress poster at the 2019 ASCO Annual Meeting in Chicago, IL. In a poster titled "A phase I study evaluating COM701 in patients with advanced solid tumors," the company reported that the sixth patient dose cohort of COM701 monotherapy has been completed and that no dose-limiting toxicities were observed in this and prior dose cohorts. Clinical and laboratory assessment for safety and tolerability are ongoing for the next higher dose cohort and for earlier dose cohorts. Furthermore, enrollment in the combination dose escalation of COM701 and Opdivo is ongoing.