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AGLE

Aeglea BioTherapeutics

$6.22

-0.29 (-4.45%)

08:49
06/03/19
06/03
08:49
06/03/19
08:49

Aeglea BioTherapeutics doses first patient in Phase 3 PEACE trial

Aeglea BioTherapeutics announced the dosing of the first patient in the company's Phase 3 PEACE clinical trial. The pivotal trial is intended to further evaluate the efficacy and safety of pegzilarginase for the treatment of Arginase 1 Deficiency, or ARG1-D, a progressive disease presenting in early childhood that results in severe complications and early mortality. The company expects to report topline data from the PEACE trial in Q1 of 2021. Aeglea anticipates reporting new data in September from all patients who have each received at least 20 doses in the company's ongoing Phase 1/2 extension study.

  • 04

    Jun

  • 07

    Jun

AGLE Aeglea BioTherapeutics
$6.22

-0.29 (-4.45%)

09/04/18
WELS
09/04/18
DOWNGRADE
WELS
Market Perform
Aeglea BioTherapeutics downgraded to Market Perform at Wells Fargo
09/04/18
09/04/18
DOWNGRADE
Target $10

Market Perform
Aeglea downgraded to Market Perform on potential development risk at Wells Fargo
As previously reported, Wells Fargo analyst Aeglea BioTherapeutics to Market Perform from Outperform on potential increased development risk following review of updated interim phase 1/2 data for pegzilarginase in Arginase 1 Deficiency. The analyst also lowered his price target on the shares to $10 from $24.
03/21/19
JPMS
03/21/19
INITIATION
Target $14
JPMS
Overweight
Aeglea BioTherapeutics initiated with an Overweight at JPMorgan
JPMorgan analyst Anupam Rama started Aeglea BioTherapeutics with an Overweight rating and $14 price target. Aeglea is an emerging player in the rare disease space and its lead asset pegzilarginase "has multiple de-risking points" for lead indication arginase 1 deficiency, Rama tells investors in a research note. This is a disease with a clear unmet need for which there are no approved therapies to directly target cause and limited competition, the analyst adds.
05/21/19
HCWC
05/21/19
INITIATION
Target $20
HCWC
Buy
Aeglea BioTherapeutics initiated with a Buy at H.C. Wainwright
H.C. Wainwright analyst Edward White started Aeglea BioTherapeutics with a Buy rating and $20 price target. The company's capital raise in February removes the financial overhang from the stock, White tells investors in a research note. He believes Aeglea shares represent an attractive investment opportunity with several potential catalysts over the next 12 months.

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