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SLNO

Soleno Therapeutics

$2.82

0.15 (5.62%)

, AVRO

Avrobio

$13.56

-0.49 (-3.49%)

08:22
06/12/19
06/12
08:22
06/12/19
08:22

Soleno Therapeutics appoints Birgitte Volck to board of directors

Soleno Therapeutics (SLNO) announced the appointment of Birgitte Volck, M.D., Ph.D. to its Board of Directors, effective June 10, 2019. Dr. Volck's appointment brings Soleno's Board of Directors to seven members, six of whom are independent. Since December 2018, Dr. Volck has served as the President R&D at AVROBIO (AVRO), a clinical stage gene therapy company.

SLNO

Soleno Therapeutics

$2.82

0.15 (5.62%)

AVRO

Avrobio

$13.56

-0.49 (-3.49%)

SLNO Soleno Therapeutics
$2.82

0.15 (5.62%)

06/22/18
ROTH
06/22/18
INITIATION
Target $14
ROTH
Buy
Soleno Therapeutics initiated with a Buy at Roth Capital
Roth Capital analyst Yasmeen Rahimi initiated Soleno Therapeutics with a Buy rating and $14 price target, stating that the company's lead asset, Diazoxide Choline Controlled-Release, has the potential to be a leader in the Prader-Wili Syndrome treatment arena.
AVRO Avrobio
$13.56

-0.49 (-3.49%)

11/27/18
LEER
11/27/18
INITIATION
Target $27
LEER
Market Perform
Avrobio initiated with a Market Perform at Leerink
Leerink analyst Mani Foroohar initiated Avrobio with a Market Perform rating and a price target of $27.
11/27/18
LEER
11/27/18
INITIATION
LEER
Leerink initiates select Genetic Medicine names on increasing regulatory clarity
Leerink analyst Mani Foroohar initiated select Genetic Medicine stocks, stating that the field is "is rich with companies developing drugs" to treat rare diseases and that he is increasingly more bullish on "innovation velocity and increasing regulatory clarity in the sector. Based on his "balanced view of pricing dynamics", the analyst issues an Outperform rating on Wave Life Sciences (WVE), Rocket Pharmaceuticals (RCKT), Intellia Therapeutics (NTLA), Eidos Therapeutics (EIDX), Dicerna (DRNA) and Bluebird Bio (BLUE). The analyst likes Wave Life Sciences as a pure play on Oligotherapeutics and its stereopure chemistry platform as a differentiated approach to oligo drug design. Foroohar is positive on Rocket Pharma's lead assets in gene therapies for Fanconi Anemia and Leukocyte Adhesion Deficiency-I "which will likely be the company's first potential approved product." The analyst is positive on Intellia Therapeutics' "robust balance sheet to support development, trading at a material discount to closest comps peers". For Eidos, the analyst cites the prospects of its drug candidate for TTR amyloidosis currently in a placebo-controlled Phase 2 study that may offer a competitive profile relative to Pfizer's (PFE) tafamidis. For Dicerna, Foroohar notes that its DCR-PHXC "is an RNAi therapeutic that targets lactate dehydrogenase A for the treatment of all subtypes of Primary Hyperoxaluria vs. competitor Alnylam's (ALNY) lumasiran, which only treats PH Type 1. For Bluebird Bio, the analyst is positive on its position as a "leader in ex vivo gene therapy, with four programs with visibility towards near-term regulatory approval". Foroohar initiates Avrobio (AVRO), Alnylam (ALNY), and Ionis Pharmaceuticals (IONS) with Market Perform rating based on competitive launches for their products along with "mixed" early signs of their results. The analyst also rates Regenxbio (RGNX) at underperform, saying that its "current valuation more than accounts for robust royalty streams from sales in spinal muscular atrophy" and other partnered assets.
01/17/19
LEER
01/17/19
NO CHANGE
Target $19
LEER
Market Perform
Avrobio price target lowered to $19 from $27 at Leerink
Leerink analyst Mani Foroohar lowered his price target for Avrobio to $19 from $27, while reiterating a Market Perform rating on the shares. While the analyst is positive on recent additions to senior management, he is more conservative on the market opportunity for Fabry gene therapy given the need for higher-intensity preconditioning regimens than the company has used previously, and believes that the potential adoption of value-based annuity pricing models by the industry could pose further risk to Avrobio's bottom line.
04/05/19
JANY
04/05/19
INITIATION
JANY
Buy
Avrobio initiated with a Buy at Janney Montgomery Scott

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CMG

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BYND

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AMZN

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BHVN

Biohaven Pharmaceutical

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CE

Celanese

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F

Ford

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RTN

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UTX

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LMT

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ARES

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HAFC

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PAYS

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MEOH

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SHIP

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SONM

Sonim

$13.42

0.24 (1.82%)

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KINS

Kingstone Companies

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AMZN

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DIS

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SKX

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PACB

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ILMN

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