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TLC

Taiwan Liposome

$5.65

-0.05 (-0.88%)

06:10
06/14/19
06/14
06:10
06/14/19
06:10

Taiwan Liposome announces part 1 analysis of Phase 2 TLC590 trial

Taiwan Liposome, or TLC, announced results from the pre-planned analysis of part 1 of TLC590's Phase 2 clinical trial in patients following bunionectomy. TLC590 is a proprietary BioSeizer liposomal formulation of ropivacaine intended for the relief of postsurgical pain. Part 1 of the two-part Phase II clinical trial, conducted in California and Utah, was a blinded safety and pharmacokinetic study to establish the tolerability and relative bioavailability of TLC590 and ropivacaine. A total of 50 patients were randomized in a ratio of 1:1:1:1 into four groups/arms to receive 152, 190 and 228mg of TLC590 or ropivacaine 50mg. Dose linearity and relative bioavailability of TLC590 have been established. All three doses of TLC590 were well tolerated, with a safety profile comparable to ropivacaine. Most treatment-emergent adverse events, or AEs, were mild to moderate in severity. There were no treatment-related or serious AEs, and no AEs leading to withdrawal. TLC590 228mg is the dose chosen to move forward based on maximum feasible volume for bunionectomy.

TLC Taiwan Liposome
$5.65

-0.05 (-0.88%)

12/17/18
JANY
12/17/18
INITIATION
Target $13
JANY
Buy
Taiwan Liposome initiated with a Buy at Janney Montgomery Scott
Janney Montgomery Scott analyst Esther Hong initiated Taiwan Liposome with a Buy rating and $13 fair value estimate, noting that the company has developed two proprietary lipid technology platforms and four clinical stage compounds across pain management, ophthalmology, and oncology. He estimates TLC599, the furthest along in development, has the potential for U.S. sales of $720M in 2028 and believes Taiwan Liposome will be a commercial stage company within a few years.
12/17/18
LDLW
12/17/18
INITIATION
Target $11
LDLW
Buy
Taiwan Liposome initiated with a Buy at Laidlaw
Laidlaw analyst Francois Brisebois initiated Taiwan Liposome (TLC) with a Buy and $11 price target saying their most important asset is TLC590, for postsurgical pain, and could potentially treat 30M US patients with osteoarthritis with a more rapid onset of actionand a longer durationthan currently available treatments. Brisebois believes TLC590 could represent an improvement over Pacira's (PCRX)'s $200M+ pain injection Expare and anticipates sales of $626M by 2027.
12/17/18
12/17/18
INITIATION

Fly Intel: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Federated Investors (FII) initiated with a Buy at Gabelli. 2. Taiwan Liposome (TLC) initiated with a Buy at H.C. Wainwright, Janney Montgomery Scott, and Laidlaw. 3. TrueCar (TRUE) initiated with a Hold at SunTrust. 4. Skechers (SKX) initiated with a Buy at Stifel. 5. Zions Bancorp (ZION) initiated with a Buy at Argus. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
12/27/18
CANT
12/27/18
INITIATION
Target $11
CANT
Overweight
Taiwan Liposome initiated with an Overweight at Cantor Fitzgerald
Cantor Fitzgerald initiated Taiwan Liposome with an Overweight and $11 price target.

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