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ATOS

Atossa Genetics

$2.27

-0.035 (-1.52%)

08:07
06/27/19
06/27
08:07
06/27/19
08:07

Atossa says preliminary Phase 2 study of Endoxifen achieves primary endpoint

Atossa Genetics announced that a preliminary analysis from its recently completed Phase 2 study of the company's proprietary 20mg daily topical Z Endoxifen showed significant and rapid reduction in mammographic breast density. Studies by others using tamoxifen have demonstrated that density reduction induced by tamoxifen is associated with a significant reduction in breast cancer incidence. A summary of preliminary results of the study follows: MBD was reduced by an average of 14.3 percent in the group applying 20mg daily topical Endoxifen, which was statistically significant. In the lower dose group, MBD was reduced by an average of 9.0 percent. These results are based on MBD measurements at the time of enrollment in the study and again at the time dosing ended, which was a mean of 55 and 88 days for the 20mg and 10mg groups, respectively. Approximately 70 percent of participants receiving 20mg topical Endoxifen experienced a reduction in MBD, and of those, the mean reduction in MBD was 27 percent. There were no significant differences in systemic endocrine or vascular side effects in the placebo versus active groups. Systemic side effects were measured using a modified validated symptom questionnaire. The most commonly experienced side effect for both groups receiving active drug were skin rashes and local irritation. The results indicate a study with approximately 50-100 subjects per dosage group would be appropriate to demonstrate efficacy for regulatory approval purposes.

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B. Riley FBR retail analyst to hold a group luncheon »

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FHN

First Horizon

$15.70

0.9 (6.08%)

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SGEN

Seattle Genetics

$63.57

-0.42 (-0.66%)

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PZZA

Papa John's

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-1.15 (-2.50%)

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Papa John's put volume heavy and directionally bearish »

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First Horizon

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Credit Suisse energy analysts to hold an analyst/industry conference call »

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CBS

CBS

$53.48

0.11 (0.21%)

, T

AT&T

$33.58

-0.12 (-0.36%)

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CBS says AT&T 'continues to propose unfair terms' »

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AT&T

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CSX

CSX

$79.47

0.95 (1.21%)

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CSX options imply 5.2% move in share price post-earnings, above median historical move »

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Fed's Evans said a little more accommodation would be helpful »

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ESV

Ensco Rowan

$8.24

-0.21 (-2.49%)

14:55
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Ensco put volume heavy and directionally bearish »

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FB

Facebook

$203.23

-0.7 (-0.34%)

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Facebook's Perault says Instagram, WhatsApp takeovers have benefited users »

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UAL

United Continental

$94.14

2.84 (3.11%)

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United Continental options imply 6.7% move in share price post-earnings, above median historical move »

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  • 17

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MNST

Monster Beverage

$65.31

0.03 (0.05%)

, PM

Philip Morris

$81.31

-0.13 (-0.16%)

14:44
07/16/19
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14:44
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14:44
Recommendations
Monster Beverage, Philip Morris, British American Tobacco, Altria Group, Nielsen analyst commentary at Wells Fargo »

Wells says Nielsen…

MNST

Monster Beverage

$65.31

0.03 (0.05%)

PM

Philip Morris

$81.31

-0.13 (-0.16%)

BTI

British American Tobacco

$36.42

-0.23 (-0.63%)

MO

Altria Group

$49.20

-0.36 (-0.73%)

NLSN

Nielsen

$23.36

-0.05 (-0.21%)

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CHFC

Chemical Financial

$40.69

-0.11 (-0.27%)

, TCF

TCF Financial

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-0.03 (-0.15%)

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Federal Reserve approves Chemical Financial deal to acquire TCF Financial »

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Chemical Financial

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-0.11 (-0.27%)

TCF

TCF Financial

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Morgan Stanley India phama analyst to hold an analyst/industry conference call »

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F

Ford

$10.43

0.015 (0.14%)

, GM

General Motors

$39.21

-0.15 (-0.38%)

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U.S. car makers open UAW contract talks as labor costs rise, WSJ reports »

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F

Ford

$10.43

0.015 (0.14%)

GM

General Motors

$39.21

-0.15 (-0.38%)

FCAU

Fiat Chrysler

$13.61

-0.565 (-3.99%)

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JBLU

JetBlue

$19.53

0.8 (4.27%)

14:25
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Options
JetBlue call volume above normal and directionally bullish »

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GOOG

Alphabet

$1,152.76

2.37 (0.21%)

14:25
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14:25
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Senate Judiciary Committee to hold a hearing »

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14:25
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Conference/Events
JPMorgan SMid Cap biotech analyst to hold an analyst/industry conference call »

SMid Biotech Analyst Fye,…

$NSD

NASDAQ Market Internals

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$NYE

NYSE Market Internals

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CFRX

ContraFect

$0.47

-0.0187 (-3.83%)

14:12
07/16/19
07/16
14:12
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14:12
Conference/Events
ContraFect management to meet with Jefferies »

Meeting to be held in New…

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  • 18

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