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ALXN

Alexion

$126.83

1.47 (1.17%)

14:16
06/27/19
06/27
14:16
06/27/19
14:16

Alexion confirms FDA approval of Soliris for treatment of NMOSD

Alexion Pharmaceuticals announced that the U.S. Food and Drug Administration approved Soliris for the treatment of neuromyelitis optica spectrum disorder, or NMOSD, in adult patients who are anti-aquaporin-4 antibody positive. Approximately three quarters of all patients with NMOSD test positive for anti-AQP4 auto-antibodies, the company said. The FDA approved Soliris following an expedited six-month priority review. NMOSD is a rare, severe autoimmune disease that attacks the central nervous system without warning. The European Medicines Agency and the Japanese Ministry of Health, Labour and Welfare are reviewing Alexion's applications to add the treatment of NMOSD to the marketing authorizations for Soliris in the European Union and Japan, respectively, the company noted.

  • 28

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  • 09

    Sep

ALXN Alexion
$126.83

1.47 (1.17%)

05/23/19
05/23/19
INITIATION
Target $173

Outperform
Alexion initiated with an Outperform at Wedbush
As previously reported, Wedbush analyst Laura Chico started Alexion with an Outperform rating and $173 price target, saying its launch of Utomiris "marks a new chapter" in the company's history amid its "conversion process" away from the flagship therapy Soliris. The analyst further contends that Ultomiris "raises the competitive bar" to offset the competition threat for Soliris, noting that the company's rich pipeline of 14 different programs and the attractive valuation add to her positive outlook on Alexion shares.
05/23/19
GSCO
05/23/19
DOWNGRADE
Target $142
GSCO
Neutral
Alexion assumed with a Neutral from Buy at Goldman Sachs
Goldman Sachs analyst Salveen Richter assumed coverage of Alexion Pharmaceuticals with a Neutral rating and $142 price target. The firm previously had a Buy rating on the shares. While the analyst sees pipeline optionality for the company, he notes a lack of definitive clinical data to date and emerging competition in gene therapy.
05/22/19
05/22/19
UPGRADE

Citi assumes coverage of large-cap biotech, upgrades Amgen and Gilead
Citi analyst Mohit Bansal assumed coverage of large-cap biotech stocks, assuming coverage with five Buy ratings -- Amgen (AMGN), Alexion Pharmaceuticals (ALXN), Vertex Pharmaceuticals (VRTX), Gilead Sciences (GILD), and BioMarin Pharmaceutical (BMRN) -- and two Neutral ratings -- Biogen (BIIB) and Regeneron Pharmaceuticals (REGN). Both Amgen and Gilead were upgraded to Buy from Neutral as part of the assumption of coverage. The analyst said he is "more optimistic" on the sector as a whole as he sees many biotechs going "back to basics" by investing in their internal pipelines and filling their pipelines with early stage assets. He suggests looking at large caps again, as many are returning to stability and growth. Bansal does not favor large M&A, suggesting discipline due to "realizing value with big M&As."
05/22/19
WEDB
05/22/19
INITIATION
Target $173
WEDB
Outperform
Alexion initiated with an Outperform at Wedbush
Wedbush analyst Laura Chico started Alexion with an Outperform rating and $173 price target.

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