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CRMD

CorMedix

$9.15

-0.07 (-0.76%)

08:51
07/08/19
07/08
08:51
07/08/19
08:51

CorMedix announces publication of taurolidine pre-clinical oncology data

CorMedix announced publication of in vitro and in vivo pre-clinical data demonstrating taurolidine's effective anti-tumor properties in pediatric neuroblastoma. The paper, entitled: "Dual Functionality of the Antimicrobial Agent Taurolidine which Demonstrates Effective Anti-tumor Properties in Pediatric Neuroblastoma" appears in the July 2019 edition of Investigational New Drugs, a peer-review journal that provides a forum for the rapid dissemination of information on new anti-cancer agents. The study investigated the in vitro activity of taurolidine against neuroblastoma using the alamar blue cytotoxicity assay, phase-contrast light microscopy, western blotting, and analysis of global gene expression by RNA-Seq. In vivo activity of taurolidine was evaluated using mouse xenograft models. The study's findings support the further investigation and evaluation of taurolidine in future pre-clinical studies and clinical trials for the treatment of pediatric neuroblastoma. Neuroblastoma is the most common extracranial solid tumor and one of the most complex and difficult-to-treat diseases in pediatric patients. The study was led by Dr. Aru Narendran, Professor of Pediatrics, Oncology, Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, with CorMedix providing financial support.

CRMD CorMedix
$9.15

-0.07 (-0.76%)

07/26/18
HCWC
07/26/18
NO CHANGE
Target $3
HCWC
Buy
CorMedix price target raised to $3 from $2 at H.C. Wainwright
H.C. Wainwright analyst Raghuram Selvaraju raised his price target for CorMedix to $3 saying the Neutrolin interim readout delivered a "home run." The analyst sees a possibility now for Neutrolin to be filed before the end of this year and to be approved in 2019, versus his original assumption that the drug would not enter the U.S. market prior to 2020. Further, the news of the clear efficacy signal in the LOCK-IT-100 study could meaningfully accelerate ex-U.S. sales of the product, the analyst adds. He reiterates a Buy rating on CorMedix.
12/06/18
ROTH
12/06/18
INITIATION
Target $6
ROTH
Buy
CorMedix initiated with a Buy at Roth Capital
Roth Capital analyst Jerry Isaacson started coverage of CorMedix with a Buy rating and $6 price target. The analyst notes that the company is developing Neutrolin for the prevention of catheter-related blood stream infections in patients with central venous catheters, and believes there is a large market opportunity for Neutrolin in multiple patient populations. CorMedix has Fast-Track designation from the FDA and QIDP designation, leading to 10.5 years of market exclusivity, he adds.
12/06/18
12/06/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. LG Display (LPL) initiated with a Buy at Citi. 2. Twitter (TWTR) and Alphabet (GOOG, GOOGL) were initiated with a Buy at Guggenheim, while Snap (SNAP) and Facebook (FB) were initiated with a Neutral. 3. Apache (APA) initiated with an Overweight at Stephens. 4. CorMedix (CRMD) initiated with a Buy at Roth Capital. 5. Protagonist Therapeutics (PTGX) initiated with a Buy at Nomura Instinet. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
12/12/18
HCWC
12/12/18
NO CHANGE
Target $3.5
HCWC
Buy
CorMedix price target raised to $3.50 from $3 at H.C. Wainwright
H.C. Wainwright analyst Raghuram Selvaraju raised his price target for CorMedix to $3.50 and reiterates a Buy rating on the shares. The analyst continues to believe that it is possible that the FDA would agree to an accelerated filing pathway for Neutrolin because of the unmet nature of the medical need with respect to catheter-related bloodstream infections and the power of the previously-reported LOCK-IT-100 interim analysis. CorMedix management have indicated that progress continues to be made towards the finalization of a New Drug Application filing on Neutrolin, Selvaraju tells investors in a research note.

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