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KURA

Kura Oncology

$20.83

0.57 (2.81%)

07:37
07/11/19
07/11
07:37
07/11/19
07:37

Kura Oncology announces new U.S., European patents for tipifarnib

Kura Oncology announced that the U.S. Patent and Trademark Office has issued and the European Patent Office has granted new patents further protecting the Company's lead drug candidate, tipifarnib, a potent and selective farnesyl transferase inhibitor. Tipifarnib is currently being studied in multiple solid tumor and hematologic indications, including a registration-directed clinical trial in HRAS mutant head and neck squamous cell carcinoma. The newly issued U.S. patents are as follows: U.S. Patent No. 10,335,404 includes multiple claims directed to a method of treating patients with HRAS mutant HNSCC consisting of administering any farnesyl transferase inhibitor; and U.S. Patent No. 10,292,979 includes multiple claims directed to the use of tipifarnib as a method of treating patients with HRAS mutant non-small cell lung carcinoma. In addition, the newly granted European patent is as follows: European Patent No. 3277842 includes multiple claims directed to the use of tipifarnib as a method of treating patients with HRAS mutant HNSCC. Each of the patents has an expiration date of August 2036, excluding any possible patent term extension.

KURA Kura Oncology
$20.83

0.57 (2.81%)

06/17/19
WEDB
06/17/19
NO CHANGE
Target $30
WEDB
Outperform
Kura Oncology price target raised to $30 from $23 at Wedbush
Wedbush analyst Robert Driscoll raised his price target for Kura Oncology to $30 from $23 after the company announced positive data from an ongoing Phase 2 study evaluating tipifarnib in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma patients carrying a CXCL12 3' UTR SNP. Overall, the analyst views the "impressive" data set as highly supportive of a registrational pathway in AITL/PTCL CXCL12+ patients, and further validating of the broadening clinical development of tipifarnib into additional indications to potentially include pancreatic, DLBCL, and AML. Driscoll reiterates an Outperform rating on the shares.
06/14/19
HCWC
06/14/19
NO CHANGE
Target $31
HCWC
Buy
Kura reported 'crucial' biomarker set of data, says H.C. Wainwright
H.C. Wainwright analyst Joseph Pantginis maintained a Buy rating and $31 price target on Kura Oncology after the company announced positive follow-up data from the ongoing Phase 2 clinical trial addressing the anti-tumor role of tipifarnib in PTCL patients and met the primary endpoint. In a research note to investors, the analyst says Kura reported a crucial biomarker set of data, the enrichment of high rate of mutation/variation of the killer cell immunoglobulin-like receptors, including KIR3DL2 in AITL patients and its role in tipifarnib outcome. Kura's targeted approaches could generate fast and meaningful information on crucial tumor indications and patient cohorts where tipifarnib may see more robust clinical outcomes, increasing his confidence on tipifarnib's likelihood of success, the analyst contends.
05/24/19
SBSH
05/24/19
NO CHANGE
Target $25
SBSH
Buy
Kura Oncology price target raised to $25 from $18 at Citi
Citi analyst Joel Beatty raised his price target for Kura Oncology to $25 from $18 saying he believes the data to date support that tipifarnib is likely effective for HRAS-mutant head and neck squamous cell carcinoma. More Phase 2 data in this setting in the second half of 2019 could add further support, Beatty tells investors in a research note. He keeps a Buy rating on Kura Oncology shares.
04/03/19
PIPR
04/03/19
NO CHANGE
PIPR
Overweight
Piper says Kura's potential patient population for tipifarnib keeps growing
After Kura Oncology presented additional data on tipifarnib, a farnesyltransferase inhibitor/HRAS inhibitor that downregulates expression of CXCL12, Piper Jaffray analyst Tyler Van Buren said the number of potential indications for the drug "continues to multiply" as initial clinical data suggest diffuse large B-cell lymphoma and cutaneous T-cell lymphoma patients could benefit from treatment in addition to the already identified cancer indications. The "broad mechanism of tipifarnib is becoming clear" and the potential patient population keeps growing, "well beyond what investors are currently appreciating," according to Van Buren. He keeps an Overweight rating on Kura shares.

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