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SBPH

Spring Bank Pharmaceuticals

$5.23

0.12 (2.35%)

11:05
07/18/19
07/18
11:05
07/18/19
11:05

Spring Bank reports agreement for HBV antisense oligonucleotide compounds

Spring Bank Pharmaceuticals announced that it has entered into a research agreement with The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to evaluate Spring Bank's hepatitis B virus antisense oligonucleotide compounds.Spring Bank has entered into a non-clinical evaluation agreement to access NIAID's preclinical services program to further evaluate Spring Bank's HBV antisense oligonucleotide compounds. Under the agreement, NIAID-funded contractors will evaluate Spring Bank's lead compounds in the HBV transgenic mouse model, a well-established preclinical model to assess compound efficacy. NIAID has previously supported the evaluation of several of Spring Bank's HBV antisense oligonucleotide compounds in antiviral in vitro assays. Spring Bank retains exclusive rights to these compounds. "We are grateful to NIAID for their support of our HBV oligonucleotide antisense program," said Kris Iyer, Ph.D., Chief Scientific Officer and Co-Founder of Spring Bank. "The research supported by this prestigious institution will enhance our knowledge of the non-clinical efficacy profile for our HBV antisense oligonucleotide R&D program."

SBPH Spring Bank Pharmaceuticals
$5.23

0.12 (2.35%)

08/14/18
PIPR
08/14/18
INITIATION
Target $25
PIPR
Overweight
Spring Bank Pharmaceuticals initiated with an Overweight at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff started Spring Bank Pharmaceuticals with an Overweight rating and $25 price target. The company has reported "encouraging" proof-of-concept data from the first three cohorts of the Phase II study of monotherapy inarigivir, in development to treat hepatitis B virus infection, Tenthoff tells investors in a research note. The analyst sees inarigivir as the "essential" immunomodulatory component in combination therapy to achieve an HBV functional cure.
10/09/18
JEFF
10/09/18
INITIATION
Target $28
JEFF
Buy
Spring Bank Pharmaceuticals initiated with a Buy at Jefferies
Jefferies analyst Maury Raycroft started Spring Bank Pharmaceuticals with a Buy rating and $28 price target. The company is developing inarigivir for hepatitis B virus and the drug is "de-risked" given its dose response and "excellent" safety profile, Raycroft tells investors in a research note. He believes inarigivir "could position as a backbone now and for the longer-term" in HBV treatment.
12/07/18
PIPR
12/07/18
NO CHANGE
Target $25
PIPR
Overweight
Spring Bank Pharmaceuticals R&D day highlights inarigivir, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff kept his Overweight rating and $25 price target on Spring Bank Pharmaceuticals after its R&D presentation yesterday. The analyst says the event highlighted the potency of inarigivir in Hepatitis B virus in patients as early as 12 weeks. Tenthoff further cites the final ACHIEVE data on the treatment likely coming at the EASL event in April of 2019, with additional studies taking place later next year.
07/01/19
PIPR
07/01/19
NO CHANGE
Target $10
PIPR
Overweight
Spring Bank price target lowered to $10 from $25 at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff noted that Spring Bank Pharmaceuticals announced it has filed an Investigational New Drug application, or IND, on SB 11285, which he said is the first intravenous administered STING agonist to advance to the clinic. After pushing out his expectation for inarigavir approval, increasing his discount rate and rolling forward his discount period, Tenthoff reset his price target on Spring Bank shares to $10 from $25. He keeps an Overweight rating on the stock.

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