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CARA

Cara Therapeutics

$25.78

-0.13 (-0.50%)

11:42
07/22/19
07/22
11:42
07/22/19
11:42

Cara Therapeutics price target raised to $31 from $28 at H.C. Wainwright

H.C. Wainwright analyst Oren Livnat analyst raised his price target for Cara Therapeutics to $31 from $28 after the company announced that the ongoing Phase 2 of oral Korsuva - its novel kappa opioid receptor agonist - in stage III-V chronic kidney disease associated pruritus in non-hemodialysis patients is fully enrolled and will not be up-sized from the original n=240 sample after the prespecified interim conditional powering analysis. The analyst believes this incrementally de-risks the likelihood of oral Korsuva Phase 2 positive results in Q4, and continues the steady run of apparent evidence supporting Korsuva's potent anti-pruritic efficacy and, importantly, no surprises on average placebo response rates. Both give him continued confidence in positive results of the ongoing KALM-2 IV Korsuva Phase 3, and the latter also underlines the intractable symptoms and unmet need in CKD-aP. Livnat has a Buy rating on the shares.

CARA Cara Therapeutics
$25.78

-0.13 (-0.50%)

05/29/19
NEED
05/29/19
NO CHANGE
Target $35
NEED
Strong Buy
Cara Therapeutics price target raised to $35 from $28 at Needham
Needham analyst Alan Carr raised his price target for Cara Therapeutics to $35 from $28 after the company reported that the Korsuva Phase 3 KALM-1 trial met all primary and secondary endpoints. Statistically significant and clinically meaningful effects were observed across pruritus and quality of life assessments, Carr tells investors in a research note. The analyst assumes the FDA will recommend Cara submit a new drug application after the "nearly identical" KALM-2 trial is completed in the second half of 2019. He keeps a Buy rating on the shares.
05/29/19
HCWC
05/29/19
NO CHANGE
Target $28
HCWC
Buy
Cara Therapeutics price target raised to $28 from $26 at H.C. Wainwright
H.C. Wainwright analyst Oren Livnat raised his price target for Cara Therapeutics to $28 from $26 saying this morning's "robust" KALM-1 results bolster his "bullish" expectations. KALM-1 delivered, with highly statistically significant results versus placebo on all primary and secondary endpoints, Livnat tells investors in a research note. The analyst adds that the general consistency from Phase 2b supports his confidence in likely success of the global KALM-2 study for which he expects topline data by Q4. Livnat maintains an "already high" 80% probability of success on IV Korsuva and keeps a Buy rating on Cara Therapeutics.
05/29/19
JEFF
05/29/19
NO CHANGE
Target $34
JEFF
Buy
Jefferies boosts Cara Therapeutics target to $34 on 'home run' data
Jefferies analyst Chris Howerton raised his price target for Cara Therapeutics to $34 from $25 saying he views the KALM-1 results as "very positive." The efficacy is a "home run" scenario, and there was no surprise in the adverse events profile, Howerton tells investors in a research note. The analyst now has increased confidence on Cara's entire pipeline. He keeps a Buy rating on the shares. Cara Therapeutics in late morning trading is up 11%, or $2.00, to $19.98.
07/01/19
PIPR
07/01/19
NO CHANGE
Target $35
PIPR
Overweight
Piper reiterates Overweight on Cara Therapeutics after nephrologist survey
Piper Jaffray analyst David Amsellem polled 25 nephrologists who manage a significant number of hemodialysis patients to gauge perceptions of the intravenous form of Cara Therapeutics' Korsuva in pruritus associated with chronic kidney disease. There is good familiarity with the body of data in the dialysis setting, most respondents perceive an unmet medical need, and most respondents have favorable impressions of Cara's data, Amsellem tells investors in a research note. The analyst says the survey reinforced our view that IV Korsuva will emerge as a valued anti-pruritic in hemodialysis patients. He views the U.S. sales opportunity "well north" of $400M-$500M and reiterates an Overweight rating on Cara Therapeutics with a $35 price target.

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