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GLYC

GlycoMimetics

$9.13

-0.1 (-1.08%)

21:09
08/04/19
08/04
21:09
08/04/19
21:09

GlycoMimetics downgraded to Neutral from Overweight at Piper Jaffray

Piper Jaffray analyst Danielle Brill downgraded GlycoMimetics to Neutral from Overweight and cut her price target for the shares to $6 from $20. The stock closed Friday down 12c to $9.13. Rivipansel failed to meet both primary and secondary endpoints in the pivotal Phase 3 sickle cell disease trial, Brill tells investors in a research note. "It hurts to admit, but we called this one completely wrong," admits the analyst. While Brill thinks it's premature to write off GlycoMimetics' uproleselan in acute myeloid leukemia, she does see the program as higher risk following the failure of rivipansel.

  • 09

    Sep

GLYC GlycoMimetics
$9.13

-0.1 (-1.08%)

05/28/19
PIPR
05/28/19
NO CHANGE
PIPR
Piper more bullish on GlycoMimetics, Global Blood into upcoming catalysts
After surveying 25 sickle cell disease experts, Piper Jaffray analyst Danielle Brill is "incrementally more bullish" on both GlycoMimetics (GLYC) and Global Blood Therapeutics (GBT) into their upcoming catalysts. GlycoMimetics and partner Pfizer (PFE) have pivotal Phase 3 results with rivipansel, their pan-selectin inhibitor, reading out in July, Brill tells investors in a research note. And Global Blood Therapeutics is expected to complete its new drug application submission for voxelotor via the accelerated approval pathway and present full Phase 3 Hope trial data in June, adds the analyst. Following expert feedback, Brill remains confident for a successful Phase 3 outcome with rivipansel. She believes positive data will drive GlycoMimetics shares "meaningfully higher" in July. Further, the majority of the surveyed doctors believe voxelotor's hemolytic anemia benefit is clinically relevant and most expect accelerated approval based on these data, adds the analyst.
06/28/19
JEFF
06/28/19
NO CHANGE
Target $19
JEFF
Buy
GlycoMimetics shares could rally 50% on rivipansel data, says Jefferies
Pfizer (PFE) is expecting data from Phase 3 testing of rivipansel, a treatment for sickle cell patients experiencing vaso-occlusive crises, in the July/August timeframe, Jefferies analyst Biren Amin tells investors in a research note. Given that GlycoMimetics (GLYC) would receive royalties on worldwide sales, the stock may move 50% on positive data and drop 40% on a negative outcome, says the analyst. He believes that while the trial is difficult to predict, the design and the enrollment of younger patients "provide some confidence of a positive outcome." Amin keeps a Buy rating on GlycoMimetics shares with a $19 price target.
07/12/19
PIPR
07/12/19
NO CHANGE
Target $20
PIPR
Overweight
GlycoMimetics risk/reward 'highly favorable' into data, says Piper Jaffray
Piper Jaffray analyst Danielle Brill thinks there is a "substantial amount of evidence" that shows clear proof-of-efficacy of GlycoMimetics' rivipansel in the sickle cell disease population. As such, the analyst remains confident that the Phase 3 data expected this quarter will be positive. The stock's risk/reward is "highly favorable," with 70%-100% upside versus downside of 20%-25% on the readout, making GlycoMimetics "even more compelling ahead of the data," Brill tells investors in a research note. She reiterates an Overweight rating on the shares with a $20 price target.
08/01/19
PIPR
08/01/19
NO CHANGE
Target $20
PIPR
Overweight
GlycoMimetics risk/reward now 'looking even better,' says Piper Jaffray
Piper Jaffray analyst Danielle Brill still thinks rivipansel has a higher probability of success than failure in the ongoing study following the recent selloff in shares of GlycoMimetics. After reviewing the bear thesis on the stock, the analyst came away positive on GlycoMimetics ahead of the imminent data. There are definite risks, but shares are trading like failure is a foregone conclusion, Brill tells investors in a research note. GlycoMimetics' risk/reward was attractive at $12 at per share, and is "looking even better at $9," contends the analyst. She keeps an Overweight rating on the stock with a $20 price target.

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