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APTX

Aptinyx

$3.52

-0.04 (-1.12%)

06:35
08/12/19
08/12
06:35
08/12/19
06:35

Aptinyx reports Q2 EPS (36c), consensus (52c)

Reports Q2 revenue $925,000, consensus $1.1M. "We made substantial business and clinical progress in the second quarter," said Norbert Riedel, Ph.D., president and CEO at Aptinyx. "The positive results on both primary and secondary endpoints in our Phase 2 study of NYX-2925 in fibromyalgia have afforded us remarkable understanding of the activity of this compound. Those results demonstrate conclusively that NYX-2925 is not only present in the brain, but also that it has positive activity on brain biomarkers known to be associated with the processing of centralized pain. Moreover, both the fibromyalgia study and the results in patients with advanced diabetic peripheral neuropathy provide evidence that this activity of NYX-2925 can result in improvement of pain and other patient-reported symptoms in these disorders. We will seek to further validate these effects on symptom alleviation in our follow-up Phase 2 studies in both fibromyalgia and DPN, to begin in the coming months. Along with our first-in-patient studies of NYX-783 in PTSD, currently enrolling, and of NYX-458 in cognitive impairment in Parkinson's disease, to kick off later this year, we will have four Phase 2 studies ongoing by the end of 2019 that will offer key development insights across our pipeline over the next 12 to 24 months."

  • 12

    Aug

APTX Aptinyx
$3.52

-0.04 (-1.12%)

01/18/19
BMOC
01/18/19
NO CHANGE
Target $18
BMOC
Outperform
Aptinyx price target lowered to $18 from $32 at BMO Capital
BMO Capital analyst Gary Nachman lowered his price target on Aptinyx to $18 after its negative result from the phase II study for NYX-2925 in diabetic peripheral neuropathy that "failed to achieve statistical significance on the primary endpoint." The analyst keeps his Outperform rating however and points to the management's "silver lining" of the drug's 50mg dose trending favorably "in a subset not on concomitant medication." Nachman adds that the program still offers "options to move forward with NYX-2925 in chronic pain" patients.
03/22/19
CANT
03/22/19
NO CHANGE
Target $12
CANT
Overweight
Aptinyx price target lowered to $12 from $18 at Cantor Fitzgerald
Cantor Fitzgerald analyst Charles Duncan lowered his price target for Aptinyx to $12 from $18 following the company's Q4 results and reiterates an Overweight rating on the shares. The target reduction reduction reflects the "overhang" created by the DPN Phase 2 readout, expectations of modest benefit in the fibromyalgia trial reading out in the first half of 2018, and the recent rapastinel trial outcome in depression that raises concerns with Aptinyx's platform more broadly, Duncan tells investors in a research note.
03/22/19
BMOC
03/22/19
NO CHANGE
Target $15
BMOC
Outperform
Aptinyx price target lowered to $15 from $18 at BMO Capital
BMO Capital analyst Gary Nachman lowered his price target on Aptinyx to $15 to reflect his longer-term revenue model adjustments, with "additional conservatism" built in for NYX-2925 after its phase 2 trial data suggested that the program is now geared to more advanced diabetic peripheral neuropathy. The analyst is keeping his Outperform rating on Aptinyx shares however, noting that the company's latest quarter results were better-than-expected on lower spending, while its $151M cash position is expected to last the company into 2021.
06/20/19
LEER
06/20/19
INITIATION
Target $12
LEER
Outperform
Aptinyx assumed with an Outperform at SVB Leerink
SVB Leerink analyst Marc Goodman assumed coverage of Aptinyx with an Outperform rating and $12 price target.

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