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PRQR

ProQR Therapeutics

$8.53

0.01 (0.12%)

07:25
08/12/19
08/12
07:25
08/12/19
07:25

ProQR Therapeutics announces FDA clearance of IND to start QR-1123 trial

ProQR Therapeutics announced that the U.S. Food and Drug Administration has cleared the Investigational New Drug application for QR-1123. ProQR plans to start enrolling patients in a Phase 1/2 trial for QR-1123 in 2019. QR-1123 is an investigational oligonucleotide designed to address the underlying cause of the vision loss associated with autosomal dominant retinitis pigmentosa due to the P23H mutation in the rhodopsin gene.

PRQR ProQR Therapeutics
$8.53

0.01 (0.12%)

12/19/18
RBCM
12/19/18
INITIATION
Target $29
RBCM
Outperform
ProQR Therapeutics initiated with an Outperform at RBC Capital
RBC Capital analyst Kennen MacKay initiated ProQR Therapeutics with an Outperform rating and a price $29. The analyst believes that the company's recent QR-110 data serves to de-risk its ophthalmology portfolio, offering "upside potential from pipeline expansion in 2019" and beyond. MacKay is also positive on ProQR Therapeutics position of having an "established proof of concept utilizing RNA-based therapies to target rare diseases uniquely sheltered from safety and efficacy challenges" faced by its therapeutic class.
01/14/19
CANT
01/14/19
NO CHANGE
CANT
Cantor highlights BioMarin, ProQR after JPMorgan Healthcare Conference
Cantor Fitzgerald analyst Eliana Merle found BioMarin's (BMRN) gene therapy platform advances and "improved risk-reward" for ProQR Therapeutics' (PRQR) USH2A program ahead of key data mid-2019 as most notable from the JPMorgan Healthcare Conference. The analyst left feeling more confident about BioMarin's gene therapy platform, which she thinks could positively surprise over the next 12-24 months as new programs enter the clinic. Further, she thinks the safety events in question at this point are likely overdone in ProQR shares following the 15% selloff since the conference. Merle now sees an "even more" favorable risk/reward into the company's mid-2019 proof-of-concept readout from a separate program.
02/20/19
SBSH
02/20/19
NO CHANGE
SBSH
Buy
Citi opens 90-day catalyst watch on ProQR Therapeutics
Citi analyst Yigal Nochomovitz opened a 90-day catalyst watch on ProQR Therapeutics in anticipation of the interim Phase 1/2 Wings data for QR-313 in dystrophic epidermolysis bullosa. On positive data, or evidence of exon skipping in biopsies and evidence of skin lesion/blister resolution, the analyst sees the stock up 15%-25%. On negative data, he sees downside of 10%-15%. Nochomovitz has a Buy rating on ProQR Therapeutics.
03/27/19
CANT
03/27/19
NO CHANGE
Target $40
CANT
Overweight
ProQR Therapeutics spin-out 'smart, but not surprising,' says Cantor Fitzgerald
Cantor Fitzgerald analyst Eliana Merle thinks ProQR Therapeutics' spin-out of its dystrophic epidermolysis bullosa program is a "smart, but not surprising," strategic move. Given that the company has communicated it wants to focus on its ophthalmology programs, investors are unlikely to find this announcement about the skin program spin-out surprising, Merle tells investors in a research note. The analyst keeps an Overweight rating on ProQR Therapeutics with a $40 price target.

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