Breaking News Instant updates and real-time market news.

ALNY

Alnylam

$78.83

-1.91 (-2.37%)

, IRWD

Ironwood

$9.09

-0.37 (-3.91%)

07:36
08/13/19
08/13
07:36
08/13/19
07:36

Alnylam, Ironwood enter GI disease promotional agreement for givosiran

Alnylam Pharmaceuticals (ALNY) and Ironwood (IRWD) announced a U.S. GI disease education and promotional agreement for Alnylam's givosiran, an investigational RNAi therapeutic targeting aminolevulinic acid synthase 1, or ALAS1, for the potential treatment of AHP. Givosiran has received priority review designation and breakthrough therapy designation from the FDA, as well as orphan drug designation in the U.S. The Prescription Drug User Fee Act date for givosiran is set for February 4, 2020. Under the terms of the agreement, Ironwood will provide AHP disease education to gastroenterologists and other healthcare practitioners that Ironwood currently calls on for Linzess. If approved by the U.S. FDA, Ironwood clinical sales specialists will then begin givosiran promotional efforts, augmenting Alnylam's broader commercialization activities. The non-exclusive agreement covers an approximately three-year term. Ironwood will collaborate with Alnylam on AHP disease education designed to help ensure AHP patients are accurately diagnosed and to support access to treatment with givosiran once prescribed. Ironwood will receive fixed payments and royalties in the mid-teens percent on net sales generated from prescriptions or referrals from certain physicians related to Ironwood's promotional efforts. Alnylam will maintain responsibility for all other aspects of givosiran, and retains all global development and commercialization rights.

ALNY

Alnylam

$78.83

-1.91 (-2.37%)

IRWD

Ironwood

$9.09

-0.37 (-3.91%)

  • 04

    Sep

  • 27

    Sep

  • 04

    Feb

ALNY Alnylam
$78.83

-1.91 (-2.37%)

05/20/19
NOMU
05/20/19
NO CHANGE
Target $62
NOMU
Reduce
Alnylam partner presented limited safety data, says Nomura Instinet
Alnylam Pharmaceuticals' (ALNY) partner, the Medicines Company (MDCO), presented on Saturday data from the ORION-3 trial of inclisiran, Nomura Instinet analyst Christopher Marai tells investors in a research note. The update did not suggest any surprise safety signals, as expected, but only limited safety data, according to Marai. He believes inclisiran's opportunity is a "show-me story" and more likely to become priced in post-approval after material sales. The analyst reiterates a Reduce rating on Alnylam shares with a $62 price target.
05/23/19
GSCO
05/23/19
DOWNGRADE
Target $80
GSCO
Neutral
Alnylam assumed with a Neutral from Buy at Goldman Sachs
Goldman Sachs analyst Salveen Richter assumed coverage of Alnylam Pharmaceuticals (ALNY) with a Neutral rating and $80 price target. The firm previously had a Buy rating on the shares. Onpattro, Alnylam's first commercial drug and key value driver, had a positive launch start, but anticipated competitive headwinds from recently approved Pfizer's tafamidis are an overhang on the shares, Richter tells investors in a research note. The analyst is on the sidelines as he assesses the drug's competitive landscape.
06/11/19
CANT
06/11/19
NO CHANGE
Target $138
CANT
Overweight
Alnylam valuation discounts givosiran opportunity, says Cantor Fitzgerald
After hosting a call with a hepatologist treating 25 acute intermittent porphyria patients, Cantor Fitzgerald analyst Alethia Young reiterates an Overweight rating on Alnylam Pharmaceuticals with a $138 price target. The stock has been under pressure due to concerns about the Onpattro launch and competitor Vyndamax, Young tells investors in a research note. However, she notes the hepatologist was positive on Alnylam's givosiran and emphasized the high unmet need. Although diagnosis will be a headwind, givosiran will see "significant uptake" in the first year of its early 2020 launch, says the analyst. She believes Alnylam's current valuation likely discounts this opportunity.
08/07/19
COWN
08/07/19
NO CHANGE
Target $120
COWN
Outperform
Alnylam price target lowered to $120 from $147 at Cowen
Cowen analyst Ritu Baral lowered her price target on Alnylam to $120 from $147 following Q2 results. The analyst noted Onpattro sales were a solid beat representing continued momentum in both the US and EU. She sees a catalyst heavy second half of the year and sustained growth in the value of its shares. Her lowered price target was based on a higher discount rate given investor sentiment around launch risk around Onpattro and competition. Baral reiterated her Outperform rating on Alnylam shares.
IRWD Ironwood
$9.09

-0.37 (-3.91%)

03/27/19
MSCO
03/27/19
UPGRADE
MSCO
Equal Weight
Ironwood upgraded to Equal Weight from Underweight at Morgan Stanley
03/27/19
MSCO
03/27/19
UPGRADE
Target $14
MSCO
Equal Weight
Morgan Stanley upgrades Ironwood to Equal Weight on more stable Linzess growth
Morgan Stanley analyst David Lebowitz upgraded Ironwood to Equal Weight from Underweight, citing his view that Linzess growth will stabilize after multiple quarters of deceleration. The withdrawal of generic MiraLAX in November 2018 will bring new patients in the near-term and new Phase 3 data expected by mid year should allow for new claims of reducing pain, discomfort and bloating, which Lebowitz thinks will bring new patients on board and help sales. Additionally, the company's spinoff of Cyclerion, expected to be completed on April 1, should lower costs and contribute to profitability, the analyst said. He raised his price target on Ironwood shares to $14 from $11.
07/10/19
FBCO
07/10/19
INITIATION
Target $14
FBCO
Neutral
Ironwood assumed with a Neutral at Credit Suisse
Credit Suisse analyst Uy Ear assumed coverage of Ironwood with a Neutral rating and $14 price target.
08/05/19
FBCO
08/05/19
INITIATION
Target $14
FBCO
Neutral
Ironwood assumed with a Neutral at Credit Suisse
Credit Suisse analyst Martin Auster assumed coverage of Ironwood with a Neutral rating and $14 price target.

TODAY'S FREE FLY STORIES

MMM

3M

$155.84

-5.04 (-3.13%)

08:58
08/24/19
08/24
08:58
08/24/19
08:58
Periodicals
3M stock still not looking like a bargain, Barron's says »

3M shares are down by…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    Oct

ULTA

Ulta Beauty

$322.34

-12.5 (-3.73%)

08:56
08/24/19
08/24
08:56
08/24/19
08:56
Periodicals
Ulta Beauty bucking downbeat retail trends, Barron's says »

Ulta Beauty has been one…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 29

    Aug

  • 25

    Sep

CMCSK

Comcast

$0.00

(0.00%)

, CMCSA

Comcast

$42.47

-1.29 (-2.95%)

08:49
08/24/19
08/24
08:49
08/24/19
08:49
Periodicals
Roku working for investors, Barron's says »

The streaming war…

CMCSK

Comcast

$0.00

(0.00%)

CMCSA

Comcast

$42.47

-1.29 (-2.95%)

DIS

Disney

$131.70

-4.37 (-3.21%)

NFLX

Netflix

$291.40

-5.47 (-1.84%)

AAPL

Apple

$202.73

-9.82 (-4.62%)

ROKU

Roku

$137.77

-1.35 (-0.97%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 04

    Sep

  • 05

    Sep

  • 23

    Sep

  • 27

    Oct

NSRGY

Nestle

$0.00

(0.00%)

08:44
08/24/19
08/24
08:44
08/24/19
08:44
Periodicals
Nestle stock looking appetizing after big gain, Barron's says »

Nestle is having a great…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

NFLX

Netflix

$291.40

-5.47 (-1.84%)

, DIS

Disney

$131.70

-4.37 (-3.21%)

08:39
08/24/19
08/24
08:39
08/24/19
08:39
Periodicals
Football season is back, key moment for TV future, Barron's says »

On Sept. 5, when the…

NFLX

Netflix

$291.40

-5.47 (-1.84%)

DIS

Disney

$131.70

-4.37 (-3.21%)

FOXA

Fox Corp.

$31.76

-1.29 (-3.90%)

CMCSK

Comcast

$0.00

(0.00%)

CMCSA

Comcast

$42.47

-1.29 (-2.95%)

CBS

CBS

$41.39

-2.06 (-4.74%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 05

    Sep

  • 23

    Sep

  • 27

    Oct

AMZN

Amazon.com

$1,752.00

-52 (-2.88%)

, FDX

FedEx

$151.94

-6.17 (-3.90%)

08:05
08/24/19
08/24
08:05
08/24/19
08:05
On The Fly
Week in review: How Trump's policies moved stocks »

Catch up on the top…

AMZN

Amazon.com

$1,752.00

-52 (-2.88%)

FDX

FedEx

$151.94

-6.17 (-3.90%)

UPS

UPS

$111.29

-3.91 (-3.39%)

F

Ford

$8.76

-0.27 (-2.99%)

GM

General Motors

$36.06

-1.19 (-3.19%)

DDAIF

Daimler AG

$0.00

(0.00%)

HMC

Honda

$22.90

-0.32 (-1.38%)

TM

Toyota

$127.94

-1.69 (-1.30%)

VWAGY

Volkswagen

$0.00

(0.00%)

AAPL

Apple

$202.73

-9.82 (-4.62%)

FB

Facebook

$177.69

-4.39 (-2.41%)

TWTR

Twitter

$41.01

-1.16 (-2.75%)

GOOGL

Alphabet Class A

$1,154.66

-35.75 (-3.00%)

GOOG

Alphabet

$1,151.72

-36.81 (-3.10%)

ADM

Archer Daniels

$37.44

-0.48 (-1.27%)

REGI

Renewable Energy

$11.65

0.61 (5.53%)

GPRE

Green Plains

$7.34

-0.68 (-8.48%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 09

    Sep

  • 15

    Sep

  • 17

    Sep

  • 17

    Sep

  • 18

    Sep

  • 19

    Sep

  • 23

    Sep

  • 24

    Sep

  • 23

    Oct

  • 23

    Oct

  • 27

    Oct

  • 13

    Nov

AMAT

Applied Materials

$45.12

-1.92 (-4.08%)

, AMD

AMD

$29.55

-2.35 (-7.37%)

04:55
08/24/19
08/24
04:55
08/24/19
04:55
Conference/Events
MUFG Securities to hold a tour »

MUFG Securities Tech Tour…

AMAT

Applied Materials

$45.12

-1.92 (-4.08%)

AMD

AMD

$29.55

-2.35 (-7.37%)

ANET

Arista Networks

$223.35

-3.84 (-1.69%)

CHKP

Check Point

$106.84

-2.36 (-2.16%)

CSCO

Cisco

$46.65

-1.55 (-3.22%)

EQIX

Equinix

$549.81

-4.27 (-0.77%)

FLEX

Flex

$9.72

-0.54 (-5.26%)

INTC

Intel

$44.97

-1.79 (-3.83%)

NVDA

Nvidia

$162.51

-8.93 (-5.21%)

OTEX

OpenText

$38.54

-0.57 (-1.46%)

PYPL

PayPal

$106.08

-2.66 (-2.45%)

RNG

RingCentral

$141.50

-0.86 (-0.60%)

SQ

Square

$61.65

-3 (-4.64%)

STX

Seagate

$46.96

-0.62 (-1.30%)

TWLO

Twilio

$127.90

-2.585 (-1.98%)

V

Visa

$175.24

-4.91 (-2.73%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Aug

  • 28

    Aug

  • 28

    Aug

  • 29

    Aug

  • 05

    Sep

  • 06

    Sep

  • 09

    Sep

  • 10

    Sep

  • 16

    Sep

  • 17

    Sep

  • 18

    Sep

  • 19

    Sep

  • 10

    Oct

  • 15

    Oct

  • 24

    Oct

  • 27

    Oct

  • 06

    Nov

  • 13

    Nov

  • 13

    Nov

  • 12

    Dec

  • 16

    Dec

DB

Deutsche Bank

$6.98

-0.19 (-2.65%)

, COF

Capital One

$83.06

-2.68 (-3.13%)

17:57
08/23/19
08/23
17:57
08/23/19
17:57
Periodicals
Deutsche Bank, Capital One won't say if they have Trump's tax returns, NYP says »

Deutsche Bank (DB) and…

DB

Deutsche Bank

$6.98

-0.19 (-2.65%)

COF

Capital One

$83.06

-2.68 (-3.13%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Oct

MXIM

Maxim Integrated

$52.14

-2.42 (-4.44%)

17:53
08/23/19
08/23
17:53
08/23/19
17:53
Hot Stocks
Maxim Integrated's Jain sells 12,683 common shares »

In a regulatory filing,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 10

    Sep

GLD

SPDR Gold Shares

$144.15

2.77 (1.96%)

17:42
08/23/19
08/23
17:42
08/23/19
17:42
Hot Stocks
SPDR Gold Shares holdings rise to 859.83MT to 854.84MT »

This is the fourth…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

AUMN

Golden Minerals

$0.27

0.0159 (6.38%)

17:33
08/23/19
08/23
17:33
08/23/19
17:33
Hot Stocks
Golden Minerals receives noncompliance notice from NYSE »

Golden Minerals announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

DMPI

DelMar Pharmaceuticals

$0.77

0.0047 (0.61%)

17:25
08/23/19
08/23
17:25
08/23/19
17:25
Hot Stocks
Intracoastal Capital reports 9.99% passive stake in DelMar Pharmaceuticals »

Intracoastal Capital…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

RTN

Raytheon

$180.58

-6.44 (-3.44%)

17:22
08/23/19
08/23
17:22
08/23/19
17:22
Hot Stocks
Raytheon awarded $534M Army contract »

Raytheon was awarded a…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

UHAL

Amerco

$339.43

-2.97 (-0.87%)

17:21
08/23/19
08/23
17:21
08/23/19
17:21
Hot Stocks
Amerco announces special cash dividend of 50c per share »

The dividend will be…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

NTLA

Intellia Therapeutics

$15.77

-1.08 (-6.41%)

17:20
08/23/19
08/23
17:20
08/23/19
17:20
Syndicate
Breaking Syndicate news story on Intellia Therapeutics »

Intellia Therapeutics…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

GD

General Dynamics

$183.42

-4.19 (-2.23%)

17:19
08/23/19
08/23
17:19
08/23/19
17:19
Hot Stocks
General Dynamics awarded $1.08B Navy contract modification »

General Dynamics has been…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

NVLN

Novelion Therapeutics

$0.66

-0.0523 (-7.37%)

17:17
08/23/19
08/23
17:17
08/23/19
17:17
Hot Stocks
Stonepine Capital reports 6.1% passive stake in Novelion Therapeutics »

Stonepine Capital…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

LMT

Lockheed Martin

$376.85

-8.91 (-2.31%)

17:14
08/23/19
08/23
17:14
08/23/19
17:14
Hot Stocks
Lockheed Martin awarded $2.43B Navy contract modification »

Lockheed Martin has been…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

ONCS

OncoSec

$1.84

-0.03 (-1.60%)

17:14
08/23/19
08/23
17:14
08/23/19
17:14
Syndicate
Breaking Syndicate news story on OncoSec »

OncoSec files $50M mixed…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

TNXP

Tonix Pharmaceuticals

$0.42

-0.0249 (-5.60%)

17:09
08/23/19
08/23
17:09
08/23/19
17:09
Syndicate
Breaking Syndicate news story on Tonix Pharmaceuticals »

Tonix Pharmaceuticals…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 25

    Sep

SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$284.86

-7.5 (-2.57%)

17:08
08/23/19
08/23
17:08
08/23/19
17:08
General News
Trump to raises tariff rates on Chinese goods, CNBC says »

U.S. President Donald…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$284.86

-7.5 (-2.57%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

ATIS

Attis Industries

$1.03

-0.08 (-7.21%)

17:06
08/23/19
08/23
17:06
08/23/19
17:06
Hot Stocks
Attis Industries provides update on status of Nasdaq listing »

Attis Industries…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

CVEO

Civeo

$1.32

-0.07 (-5.04%)

17:04
08/23/19
08/23
17:04
08/23/19
17:04
Syndicate
Breaking Syndicate news story on Civeo »

Civeo files $300M mixed…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

AGO

Assured Guaranty

$42.56

-1.09 (-2.50%)

16:58
08/23/19
08/23
16:58
08/23/19
16:58
Hot Stocks
Assured Guaranty CEO sells 30,300 common shares »

In a regulatory filing,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

RMED

Ra Medical Systems

$1.87

-0.055 (-2.86%)

16:50
08/23/19
08/23
16:50
08/23/19
16:50
Hot Stocks
Ra Medical Systems discloses NYSE notice related to 10-Q filing delay »

Ra Medical Systems…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.