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RUBY

Rubius Therapeutics

$11.24

-0.51 (-4.34%)

08:16
08/13/19
08/13
08:16
08/13/19
08:16

Rubius Therapeutics expects to report data from Phase 1b trial by year-end

Rubius is working closely with its contract manufacturer to improve its ability to consistently produce product in 200-liter bioreactors in order for Rubius to begin enrolling patients in its Phase 1b clinical trial for patients with phenylketonuria (PKU) in the near term. Rubius plans to report initial clinical data from the first patients enrolled in the trial by year-end, including: Preliminary safety; Longevity of RTX-134 cells in circulation; and Proof-of-mechanism as measured by production of trans-cinnamic acid, the metabolite of phenylalanine when degraded by phenylalanine ammonia lyase, or PAL.

  • 09

    Sep

RUBY Rubius Therapeutics
$11.24

-0.51 (-4.34%)

05/30/19
GUGG
05/30/19
INITIATION
Target $25
GUGG
Buy
Rubius Therapeutics initiated with a Buy at Guggenheim
Guggenheim analyst Michael Schmidt started Rubius Therapeutics with a Buy rating and $25 price target.
05/30/19
05/30/19
INITIATION
Target $25

Buy
Rubius Therapeutics, Fate Therapeutics initiated with a Buy at Guggenheim
As previously reported, Guggenheim analyst Michael Schmidt initiated Rubius Therapeutics (RUBI) and Fate Therapeutics (FATE) with a Buy rating and Allogene Therapeutics (ALLO) with a Neutral rating as part of a broader research note of 3 biotechnology stocks that developed "innovative" next-gen cell therapy platforms. The analyst has a $25 price target on Fate Therapeutics, saying the company could "leapfrog" competitors by applying its induced pluripotent stem cell, or iPSC, platform toward "engineered off-the-shelf cancer immunotherapies in a dish". While still at an early stage, Schmidt says the platform may improve upon its initial shortcomings in first and also second generation cellular cancer immunotherapies toward a broad set of therapeutic areas. The analyst is also positive on the "unique red cell therapeutics platform" of Rubius Therapeutics and its upcoming proof-of-concept data in the second half of this year, with an "extremely broad" range of potential applications including rare genetic diseases to cancer and autoimmune diseases. Schmidt also assigns $25 price target to Rubius. For Allogene Therapeutics, Schmidt says he is positive on its potential front-runner status in bringing off-the-shelf CAR-T to market, but sees much of its potential having been priced into the stock.
06/26/19
HCWC
06/26/19
INITIATION
Target $40
HCWC
Buy
Rubius Therapeutics initiated with a Buy at H.C. Wainwright
H.C. Wainwright analyst Andrew Fein initiated Rubius Therapeutics with a Buy rating and $40 price target, stating that he believes the company can generate Red Cell Therapeutics with "unprecedented efficiency." He thinks that Rubius' pipeline diversity and platform strength are underappreciated ahead of the first-in-human data for RTX-134 in phenylketonuria, which is due in the second half of the year.
07/11/19
HCWC
07/11/19
NO CHANGE
Target $40
HCWC
Buy
Rubius' RTX-240 offers differentiated value propositions, says H.C. Wainwright
H.C. Wainwright analyst Andrew Fein believes Rubius Therapeutics' RTX-240 offers differentiated value propositions that are being underappreciated by the market. The analyst has a bullish view on IL-15 in cancer treatment and RTX-240's "competitive strength" RTX-240 differentiates by presenting the natural conformation of IL-15/IL-15R-alpha, synergistic effects from 4-1BBL and improved safety profile with vascular bio-distribution, Fein tells investors in a research note. He keeps a Buy rating on Rubius Therapeutics with a $40 price target.

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