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INNT

Innovate Biopharmaceuticals

$0.84

-0.0344 (-3.93%)

09:11
08/13/19
08/13
09:11
08/13/19
09:11

Innovate Biopharmaceuticals announces first patient dosed in Phase 3 trial

Innovate Biopharmaceuticals announced that it has dosed the first patient in its Phase 3 clinical trial, CeD LA 3001. This marks the first time any company has dosed a patient in a Phase 3 trial for celiac disease. Larazotide acetate, or INN-202, is Innovate's leading drug candidate for the treatment of celiac disease. The drug is a tight junction regulator designed to help restore "leaky" or open junctions to a normal state. Celiac disease affects approximately 1% of the U.S. population, more than 3 million Americans, and is a high unmet need with no FDA approved treatments. This Phase 3 study is a national, multicenter, double-blind, placebo-controlled, randomized, parallel-group trial that is expected to enroll approximately 600 patients. The study's primary objective is to evaluate larazotide acetate as an adjunct therapy for patients with celiac disease who still experience symptoms despite being on a gluten-free diet. Larazotide is an oral therapy taken prior to meals, up to 3 times per day. Larazotide is not systemically absorbed and has a well-established safety profile.

INNT Innovate Biopharmaceuticals
$0.84

-0.0344 (-3.93%)

07/01/19
HCWC
07/01/19
NO CHANGE
Target $10
HCWC
Buy
Innovate price target lowered to $10 from $35 at H.C. Wainwright
H.C. Wainwright analyst Raghuram Selvaraju lowered his price target for Innovate Biopharmaceuticals to $10 from $35 while reiterating a Buy rating on the shares. Following completion of multiple recent financing transactions, the analyst increased Innovate's fully-diluted shares outstanding to roughly 59M, which reduced his price target. He also pushed out the projected timelines for launch of Innovate's drug candidates to reflect the current timing of clinical development. However, in anticipation of clinical progress medium-term, including the completion of patient enrollment in the Phase 3 program for INN-202 in celiac disease, Selvaraju keeps a Buy rating on the name.

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  • 27

    Oct

MXIM

Maxim Integrated

$52.14

-2.42 (-4.44%)

17:53
08/23/19
08/23
17:53
08/23/19
17:53
Hot Stocks
Maxim Integrated's Jain sells 12,683 common shares »

In a regulatory filing,…

03/08/13
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  • 10

    Sep

GLD

SPDR Gold Shares

$144.15

2.77 (1.96%)

17:42
08/23/19
08/23
17:42
08/23/19
17:42
Hot Stocks
SPDR Gold Shares holdings rise to 859.83MT to 854.84MT »

This is the fourth…

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