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SRPT

Sarepta

$120.16

-4.81 (-3.85%)

07:41
08/20/19
08/20
07:41
08/20/19
07:41

Sarepta price target lowered to $175 from $231 at Cantor Fitzgerald

Cantor Fitzgerald analyst Alethia Young cut her price target on Sarepta shares to $175 from $231 after the company announced the receipt of a complete response letter, or CRL, on golodirsen from the FDA. After speaking with Sarepta management, Young now expects a delay of at least one year. The analyst, who previously assumed 100% success for both golodirsen and casimersen, sees greater approval risk and lowered her view on the probability of success to 40% for both programs. Young, who believes some aspects of the FDA's pushback could be political, and therefore hard to handicap, keeps an Overweight rating on Sarepta shares, which are down $20.54, or 17%, to $99.77 in pre-market trading.

SRPT Sarepta
$120.16

-4.81 (-3.85%)

08/19/19
LEER
08/19/19
UPGRADE
Target $15
LEER
Outperform
Solid Biosciences upgraded to Outperform with $15 target at SVB Leerink
As previously reported, SVB Leerink analyst Joseph Schwartz upgraded Solid Biosciences (SLDB) to Outperform from Market Perform after reassessing the protocol amendments and enrollment progress communicated by the company for its Phase 1/2 IGNITE-DMD trial. He believes much of the concerns that have weighed on the stock are baked-in at this point and continues to believe that Solid's scalable manufacturing "could be an underappreciated X-factor" that could potentially help it catch-up to the leader in the DMD space, Sarepta (SRPT). Schwartz raised his price target on Solid shares to $15 from $8.
08/20/19
JMPS
08/20/19
NO CHANGE
Target $270
JMPS
Outperform
Sarepta price target lowered to $270 from $275 at JMP Securities
JMP Securities analyst Liisa Bayko lowered her price target on Sarepta to $270 after the company's disclosure of an FDA a Complete Response Letter regarding the deficiencies of its golodirsen, but keeps her Outperform rating and sees the weakness as an opportunity to buy more share. The analyst notes that while approval was largely expected, golodirsen only represented about $6 in stock value. Bayko adds that she still expects golodirsen to launch, but not until 2021 vs. prior forecast of Q3 of this year, also lowering the probability of success to 60% from 70%.
08/20/19
PIPR
08/20/19
NO CHANGE
Target $185
PIPR
Overweight
Sarepta price target lowered to $185 from $208 at Piper Jaffray
Piper Jaffray analyst Danielle Brill lowered her price target for Sarepta to $185 from $208 after the company's disclosure of an FDA a Complete Response Letter regarding the deficiencies of its golodirsen, but kept her Overweight rating. Brill tells investors in a research note that "it certainly feels like there may be more" behind the FDA's decision to issue a CRL than the reasons cited, and says "it does not appear to be something that can be [easily] reconciled." Brill says she is still bullish for gene-tx, but notes more downside risk without support from golodirsen and casimersen.
08/20/19
HCWC
08/20/19
NO CHANGE
Target $160
HCWC
Buy
Sarepta price target lowered to $160 from $267 at H.C. Wainwright
H.C. Wainwright analyst Debjit Chattopadhyay said the CRL from the FDA for golodirsen "came as a rude surprise" and was "seemingly arbitrary." The potential for renal issues, which was not reported in the clinical program, could be weighing on the FDA's decision, or the CRL could be a signal of a more circumspect agency, which would require clinical evidence to align with surrogate markers to justify accelerated approval, said the analyst, who can't say which it might be. In the absence of more information, he is eliminating golodirsen and casimersen from his model and lowering his price target on Sarepta shares to $160 from $267. If there is indeed a change of mindset at the agency, it could be a multi-year wait for exon-53 and -45 amenable subjects, added the analyst, who keeps a Buy rating on Sarepta.

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$39.05

-0.5 (-1.26%)

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$3,632.55

-30.45 (-0.83%)

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