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ABBV

AbbVie

$66.04

0.34 (0.52%)

08:47
08/29/19
08/29
08:47
08/29/19
08:47

AbbVie discontinues Rova-T research and development program

AbbVie announced that MERU, a Phase 3 trial evaluating Rova-T as a first-line maintenance therapy for advanced small-cell lung cancer, demonstrated no survival benefit at a pre-planned interim analysis for patients receiving Rova-T as compared with placebo. The overall safety profile was generally consistent with that observed in previous studies. The MERU trial is being closed, and the Rova-T research and development program has been terminated. AbbVie will move forward prioritizing other development programs within its oncology pipeline. An Independent Data Monitoring Committee recommended terminating MERU due to lack of survival benefit for patients receiving Rova-T compared with the placebo control arm based on results at a pre-planned interim analysis. Results from the MERU trial will be presented at a future medical meeting and/or published in a peer-reviewed medical journal. "Small-cell lung cancer continues to be one of the most difficult-to-treat cancers where there is a significant need for transformative therapies. We are disappointed with this outcome for the patients who suffer from this disease," said Margaret Foley, M.D., vice president, global head of solid tumor development, AbbVie. "We remain committed to researching and developing other therapies with the potential to transform care for patients with small-cell lung cancer and other malignancies."

  • 09

    Sep

  • 16

    Sep

ABBV AbbVie
$66.04

0.34 (0.52%)

08/16/19
CANT
08/16/19
NO CHANGE
CANT
Rinvoq read through 'very positive' for Theravance, says Cantor Fitzgerald
Cantor Fitzgerald analyst Louise Chen said the FDA approval of AbbVie's (ABBV) Rinvoq with a black box warning was "very positive" for Theravance Biopharma (TBPH), as Theravance's TD-1473 is "likely the only JAK in development that may not receive a black box warning." Chen maintained an Overweight rating and $55 price target on Theravance Biopharma.
08/16/19
PIPR
08/16/19
NO CHANGE
PIPR
Neutral
Piper says uptake of AbbVie's Rinvoq should be 'robust' despite black box
Piper Jaffray analyst Christopher Raymond said the approval of Rinvoq ahead of Monday's PDUFA date was "generally in line with expectations" in terms of timing. While Rinvoq did not avoid the black box class labeling seen with other JAKs, he thinks based on his previous survey work that uptake of the drug should "both be robust and minimally impactful to Humira." Raymond keeps a Neutral rating on AbbVie (ABBV) shares, citing his concerns about Humira pressure and over the planned combination with Allergan (AGN).
08/20/19
PIPR
08/20/19
UPGRADE
Target $80
PIPR
Overweight
AbbVie upgraded to Overweight from Neutral at Piper Jaffray
Piper Jaffray analyst Christopher Raymond upgraded AbbVie (ABBV) to Overweight with a price target of $80, saying that while he remains negative on the company's decision to acquire Allergan (AGN), he believes that a bottom on the stock has been found around $66. The analyst adds that he also has concerns about tthe "various pressure points" on AbbVie's Humira business, but he also sees "great opportunity" for the company to leverage its successful launches of Skyrizi and Rinvoq, along with anticipating a "rather durable" Botox cosmetic franchise going forward.
08/20/19
08/20/19
UPGRADE

Fly Intel: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Pilgrim's Pride (PPC) upgraded to Outperform from Market Perform at BMO Capital with analyst Kenneth Zaslow citing the management's implementation of a "successful execution" of its chicken strategy. 2. Beyond Meat (BYND) upgraded to Overweight from Neutral at JPMorgan while Campbell Soup (CPB) was upgraded to Neutral from Underweight. 3. Chemours (CC) upgraded to Positive from Neutral at Susquehanna with analyst Don Carson saying he thinks end-user destocking of TiO2 appears to have run its course and he views the company as the prime beneficiary of an upturn in industry volumes in 2020. 4. AbbVie (ABBV) upgraded to Overweight from Neutral at Piper Jaffray with analyst Christopher Raymond saying while he remains negative on the company's decision to acquire Allergan (AGN), he believes that a bottom on the stock has been found around $66. 5. CACI (CACI) upgraded to Outperform from Neutral at Credit Suisse with analyst Robert Spingarn saying in an uncertain macro environment, he likes a defensive name that can support a multi-year story of organic growth, margin expansion, and M&A optionality, all while offering an attractive valuation. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

QGEN

Qiagen

$34.98

0.805 (2.36%)

15:05
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Options
Qiagen call volume above normal and directionally bullish »

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  • 05

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QGEN

Qiagen

$35.08

0.905 (2.65%)

15:04
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Qiagen rises after CTFN says company talking to interested party »

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  • 05

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HEXO

Hexo

$1.61

-0.17 (-9.55%)

15:00
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Recommendations
Hexo analyst commentary  »

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General news
Treasury Action: the markets are little changed »

Treasury Action: the…

QGEN

Qiagen

$34.34

0.165 (0.48%)

14:51
01/17/20
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Periodicals
Qiagen shares up 3% to $35.15 in afternoon trading »

CTFN's Diane Alter…

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  • 05

    Feb

SWK

Stanley Black & Decker

$171.74

1.29 (0.76%)

14:49
01/17/20
01/17
14:49
01/17/20
14:49
Periodicals
Stanley Black & Decker in talks to buy Consolidated Aerospace, Reuters says »

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  • 29

    Jan

AAPL

Apple

$316.97

1.64 (0.52%)

14:49
01/17/20
01/17
14:49
01/17/20
14:49
Periodicals
Apple may have to abandon lightning connector cable in Europe, BBC News says »

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  • 28

    Jan

SWK

Stanley Black & Decker

$171.72

1.27 (0.75%)

14:45
01/17/20
01/17
14:45
01/17/20
14:45
Periodicals
Stanley Black & Decker in talks to buy Consolidated Aerospace, Reuters says »

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  • 29

    Jan

LSCC

Lattice Semiconductor

$23.15

1.87 (8.79%)

, AAPL

Apple

$316.57

1.24 (0.39%)

14:39
01/17/20
01/17
14:39
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14:39
Hot Stocks
Lattice Semiconductor rises as link to Apple acquisition highlighted »

Following a report from…

LSCC

Lattice Semiconductor

$23.15

1.87 (8.79%)

AAPL

Apple

$316.57

1.24 (0.39%)

03/08/13
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  • 28

    Jan

DB

Deutsche Bank

$8.43

-0.115 (-1.35%)

14:32
01/17/20
01/17
14:32
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14:32
Periodicals
Deutsche Bank slashes investment bank bonuses by roughly 30%, Bloomberg says »

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  • 30

    Jan

14:30
01/17/20
01/17
14:30
01/17/20
14:30
Options
MIAX SPIKES options volume over 100K contracts is new record »

MIAX SPIKES options…

INSG

Inseego

$9.23

0.76 (8.97%)

14:25
01/17/20
01/17
14:25
01/17/20
14:25
Options
Inseego call volume above normal and directionally bullish »

Bullish option flow…

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NSTG

NanoString

$30.44

-0.41 (-1.33%)

14:23
01/17/20
01/17
14:23
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14:23
Hot Stocks
Pura Vida reports 5.37% passive stake in NanoString »

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  • 06

    Feb

$NSD

NASDAQ Market Internals

$0.00

(0.00%)

14:17
01/17/20
01/17
14:17
01/17/20
14:17
Technical Analysis
NASDAQ market internals summary »

Volume is above average…

03/08/13
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$NYE

NYSE Market Internals

$0.00

(0.00%)

14:16
01/17/20
01/17
14:16
01/17/20
14:16
Technical Analysis
NYSE market internals summary »

Volume is average for…

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ENV

Envestnet

$70.39

-4.05 (-5.44%)

14:06
01/17/20
01/17
14:06
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14:06
Hot Stocks
Lawmakers urge FTC to investigate Envestnet over sale of financial data »

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  • 24

    Feb

SNCA

Seneca Biopharma

$3.80

2.55 (204.00%)

14:06
01/17/20
01/17
14:06
01/17/20
14:06
Syndicate
Seneca Biopharma announces exercise of warrants for $7.55M gross proceeds »

Seneca Biopharma…

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DHT

DHT Holdings

$7.41

0.19 (2.63%)

14:05
01/17/20
01/17
14:05
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Options
DHT Holdings call volume above normal and directionally bullish »

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14:05
01/17/20
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General news
Action Economics Survey results: »

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BGNE

BeiGene

$169.60

1.72 (1.02%)

14:03
01/17/20
01/17
14:03
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14:03
Upgrade
BeiGene rating change  »

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03/08/13
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  • 27

    Feb

SNE

Sony

$72.46

-0.09 (-0.12%)

, CMCSA

Comcast

$47.43

0.57 (1.22%)

13:57
01/17/20
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On The Fly
Box Office Battle: 'Bad Boys for Life' opens strong »

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SNE

Sony

$72.46

-0.09 (-0.12%)

CMCSA

Comcast

$47.43

0.57 (1.22%)

CMCSK

Comcast

$0.00

(0.00%)

T

AT&T

$38.33

0.3 (0.79%)

DIS

Disney

$144.67

-0.43 (-0.30%)

LGF.A

Lionsgate

$10.94

-0.34 (-3.01%)

LGF.B

Lionsgate

$10.30

-0.325 (-3.06%)

VIAC

ViacomCBS

$39.64

-0.41 (-1.02%)

03/08/13
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  • 23

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  • 04

    Feb

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  • 06

    Feb

  • 06

    Feb

BA

Boeing

$325.18

-6.82 (-2.05%)

13:46
01/17/20
01/17
13:46
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13:46
Periodicals
Boeing tells CNBC 'making necessary updates' to MAX after report of new issue »

After ABC's David…

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  • 29

    Jan

BA

Boeing

$326.24

-5.76 (-1.73%)

13:43
01/17/20
01/17
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13:43
Hot Stocks
Breaking Hot Stocks news story on Boeing »

Boeing down 2% to $325.88…

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  • 29

    Jan

VB

Vanguard Small-Cap Index Fund

$169.72

-0.13 (-0.08%)

, IVV

iShares Core S&P 500

$333.10

0.72 (0.22%)

13:43
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Technical Analysis
On The Fly: ETF fund flow highlights »

For the week creations…

VB

Vanguard Small-Cap Index Fund

$169.72

-0.13 (-0.08%)

IVV

iShares Core S&P 500

$333.10

0.72 (0.22%)

TLT

iShares 20+ Year Treasury Bond Fund

$138.05

-1.15 (-0.83%)

ESGU

iShares ESG MSCI U.S.A. ETF

$73.74

0.27 (0.37%)

VCSH

Vanguard Short-Term Corporate Bond Index Fund

$81.21

0.025 (0.03%)

SPY

SPDR S&P 500 ETF Trust

$331.63

0.73 (0.22%)

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BA

Boeing

$326.27

-5.73 (-1.73%)

13:42
01/17/20
01/17
13:42
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13:42
Periodicals
ABC learns of another software issue with Boeing 737 Max »

ABC's David Kerley…

03/08/13
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  • 29

    Jan

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