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MRNA

Moderna

$15.74

0.55 (3.62%)

, TBIO

Translate Bio

$9.04

-0.19 (-2.06%)

07:40
08/31/19
08/31
07:40
08/31/19
07:40

Translate Bio, Moderna chasing next frontier in treating disease, Barron's says

Lots of diseases are caused by a single missing protein and if one could get the trick to work on one of those diseases, it could work for many of them, a thrilling idea that has many looking to make a drug of a messenger ribonucleic acid, or mRNA, Josh Nathan-Kazis writes in this week's edition of Barron's. The theoretical simplicity of the concept has attracted more than $5B in capital to the four biotech companies leading the research on the idea, including Translate Bio (TBIO), the author adds, noting that Moderna (MRNA) is the largest mRNA company. The only question remaining is whether it works, the publication says. Reference Link

MRNA

Moderna

$15.74

0.55 (3.62%)

TBIO

Translate Bio

$9.04

-0.19 (-2.06%)

  • 09

    Sep

  • 12

    Sep

MRNA Moderna
$15.74

0.55 (3.62%)

05/29/19
OPCO
05/29/19
NO CHANGE
Target $31
OPCO
Outperform
Moderna price target raised to $31 from $27 at Oppenheimer
Oppenheimer analyst Hartaj Singh raised his price target for Moderna to $31 from $27 after spending time with management. The analyst was "consistently impressed" with the updates on safety, manufacturing, and increasing dosing experience of various Moderna therapeutics in different modalities. He reiterates an Outperform rating on the shares.
06/20/19
PIPR
06/20/19
NO CHANGE
Target $30
PIPR
Overweight
Moderna recent weakness a buying opportunity, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff recommends using the recent weakness in shares of Moderna as a buying opportunity. The stock is down 19% on increased volume since the initial public offering lock-up expiry on June 5, Tenthoff tells investors in a research note. The analyst is most focused on the Phase I chikungunya antibody data in the second half of 2019, which he believes will have read-through to Moderna's growing orphan disease pipeline. He reiterates an Overweight rating on the shares with a $30 price target.
07/24/19
MSCO
07/24/19
NO CHANGE
MSCO
Warming could create need for up to $125B more vaccinations, says Morgan Stanley
Morgan Stanley analysts led by Matthew Harrison offered a report sizing the impact on biopharma from climate change. They conclude that warmer temperatures are likely to create more hospitable environments for disease transmission and they cite recent research that suggests 385M-725M more people than today may be exposed to infectious diseases such as dengue, Zika, chickungunya, and yellow fever by 2050. They estimate $50B-$125B of incremental vaccinations may be needed, but see the potential for that figure to be as high as $200B with branded pricing of more complicated vaccines. The companies best positioned to benefit from a rising need for infectious disease vaccines include Sanofi (SNY), GlaxoSmithKline (GSK), Moderna (MRNA), Merck (MRK), Johnson & Johnson's (JNJ) Janssen, Pfizer (PFE) and Takeda (TAK), according to Harrison and the team.
08/16/19
PIPR
08/16/19
NO CHANGE
Target $30
PIPR
Overweight
Moderna should be bought ahead of catalysts, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff recommends buying shares of Moderna on weakness ahead of the company's R&D day on September 12. Moderna has completed enrollment of the Phase I study of cytomegalovirus vaccine mRNA-1647 with data soon, and the company could also report preliminary Phase I data on intratumoral mRNA-2754 by the end of 2019, Tenthoff tells investors in a research note. Further, the analyst is focused on the Phase I chikungunya antibody mRNA-1944 data in Q4 for read-through to Moderna's orphan disease pipeline. He sees multiple clinical data readouts through the end of the year and reiterates an Overweight rating on the shares with a $30 price target.
TBIO Translate Bio
$9.04

-0.19 (-2.06%)

01/22/19
PIPR
01/22/19
NO CHANGE
Target $24
PIPR
Overweight
Translate clinical hold has no read-through to Moderna, says Piper Jaffray
Moderna's (MRNA) messenger RNA competitor Translate Bio (TBIO) announced this morning that the FDA placed a clinical hold on its Investigational New Drug Application for MRT5201 to treat ornithine transcarbamylase deficiency, Piper Jaffray analyst Edward Tenthoff tells investors in a research note. Translate Bio also had a prior clinical IND hold on MRT5005 for cystic fibrosis due to manufacturing issues, adds the analyst. Tenthoff does not see read-through to Moderna's mRNA platform and pipeline from the news. The FDA accepted the company's IND for mRNA-3704 to treat orphan disease methylmalonic acidemia, and the Phase I/II study will begin soon, says the analyst. He reiterates an Overweight rating on Moderna with a $24 price target. The stock in midday trading is down 3% to $16.15.
06/18/19
ROTH
06/18/19
INITIATION
Target $25
ROTH
Buy
Translate Bio initiated with a Buy at Roth Capital
Roth Capital analyst Tony Butler started coverage of Translate Bio (TBIO) with a Buy rating and a $25 price target. The analyst believes that with its engineered mRNA and LPN delivery vehicles, Translate Bio's MRT platform has the advantages of enhanced stability, lower immunogenicity, tissue-specific delivery, and potentially scalable manufacturing. Butler also sees Sanofi (SNY) partnership providing resources and broadening the pipeline.
06/18/19
06/18/19
INITIATION

Fly Intel: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. ViewRay (VRAY) initiated with an Overweight at Piper Jaffray. 2. Premier (PINC) initiated with a Neutral at Guggenheim. 3. Stealth Biotherapeutics (MITO) initiated with a Buy at H.C. Wainwright. 4. Twilio (TWLO) initiated with a Buy at Needham. 5. Translate Bio (TBIO) initiated with a Buy at Roth Capital. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
07/22/19
JEFF
07/22/19
INITIATION
Target $20
JEFF
Buy
Translate Bio initiated with a Buy at Jefferies
Jefferies analyst Eun Yang started Translate Bio with a Buy rating and $20 price target. The company's first human Phase 1/2 efficacy data in 2020, if positive, will provide "meaningful upside" in the shares, Yang tells investors in a research note.

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PTON

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PINS

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06:45
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CMG

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06:42
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BA

Boeing

$344.09

-25.04 (-6.78%)

06:39
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Downgrade
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  • 23

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GIL

Gildan Activewear

$26.27

-9.105 (-25.74%)

06:36
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  • 31

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OPRT

Oportun Financial

$15.89

-0.22 (-1.37%)

06:36
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ONB

Old National Bancorp

$17.19

0.11 (0.64%)

06:35
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Earnings
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  • 21

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GIL

Gildan Activewear

$26.27

-9.105 (-25.74%)

06:33
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06:33
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  • 31

    Oct

KNOP

KNOT Offshore Partners

$19.50

0.02 (0.10%)

06:32
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  • 21

    Nov

BXBLY

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$0.00

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06:29
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CVX

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BA

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PTON

Peloton

$23.44

-0.41 (-1.72%)

06:19
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DTE

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