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ATOS

Atossa Genetics

$1.95

-0.07 (-3.47%)

08:15
09/03/19
09/03
08:15
09/03/19
08:15

Atossa Genetics completes enrollment, dosing in Phase 1 trial of Endoxifen

Atossa Genetics announced that all participant activities have been completed in its Phase 1 clinical trial of a new proprietary modified-release oral tablet form of its Endoxifen. This is the next generation of oral Endoxifen following the successful clinical studies of the capsule form of the company's oral Endoxifen. The Phase 1 study is being conducted in Australia. The objectives of the study are to assess safety and tolerability and to ascertain the pharmacokinetics of the tablet. The study is randomized, double-blinded and placebo-controlled with both single and multiple-doses in two groups with a total of 24 healthy female volunteers. Atossa's oral Endoxifen capsule served as the comparator.

ATOS Atossa Genetics
$1.95

-0.07 (-3.47%)

06/27/19
MAXM
06/27/19
DOWNGRADE
MAXM
Hold
Atossa Genetics downgraded to Hold from Buy at Maxim
Maxim analyst Jason McCarthy downgraded Atossa Genetics to Hold from Buy.
06/27/19
MAXM
06/27/19
DOWNGRADE
MAXM
Hold
Maxim downgrades Atossa Genetics to Hold on high endoxifen discontinuations
As previously reported, Maxim analyst Jason McCarthy downgraded Atossa Genetics to Hold from Buy after the company announced results from its Phase 2 study evaluating topical endoxifen in patients with mammographic breast density. Topical endoxifen showed a signal of efficacy and the trial hit its primary endpoint, but an 80% discontinuation rate due to skin rashes and local irritation raises questions and leaves him with doubt about the program, McCarthy tells investors. Based on his questions about the next steps and potential for short-term use, lower dose, or alternate delivery route, McCarthy removed topical endoxifen from his model and removed his prior price target of $9 on Atossa shares.

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