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PHAS

PhaseBio

$8.56

-0.28 (-3.17%)

08:42
09/03/19
09/03
08:42
09/03/19
08:42

PhaseBio announces data from evaluation of pharmacodynamics of PB2452

PhaseBio Pharmaceuticals announced that data from an evaluation of the pharmacodynamics of PB2452, a novel reversal agent for the antiplatelet drug ticagrelor, were presented by Lisa K. Jennings, Ph.D., Professor of Medicine, University of Tennessee Health Science Center, at ESC Congress 2019 in Paris on September 1. The first-in-human, randomized, double-blind, placebo-controlled Phase 1 clinical trial evaluated the safety, efficacy and pharmacokinetics of intravenous PB2452 as a ticagrelor reversal agent in 64 healthy volunteers aged 18 to 50 years. Platelet function was assessed using light transmission aggregometry, VerifyNow PRUTest and vasodilator stimulated phosphoprotein assays. VerifyNow PRUTest is considered to be the gold standard for point-of-care assessments of platelet function. The data demonstrated that complete reversal by all measurements occurred within 15 minutes of administration and was sustained for over 20 hours. PhaseBio has continued to use the same three assays to demonstrate the efficacy of PB2452 in a Phase 2a trial and has continued to see a high degree of correlation among the assays in both trials.

PHAS PhaseBio
$8.56

-0.28 (-3.17%)

11/12/18
COWN
11/12/18
INITIATION
COWN
Outperform
PhaseBio initiated with an Outperform at Cowen
Cowen analyst Phil Nadeau initiated PhaseBio with an Outperform rating, noting its lead candidate is a reversal agent for the anti-platelet drug ticagrelor. He projects the drug to achieve $785M in worldwide sales by 2028. Nadeau has not established a price target on PhaseBio shares.
11/12/18
11/12/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Denali Therapeutics (DNLI) initiated with a Buy at Janney Montgomery Scott. 2. PhaseBio (PHAS) initiated with a Buy at Stifel and Citi as well as an Outperform at Cowen. 3. Osmotica Pharmaceuticals (OSMT) initiated with a Buy at Jefferies as well as an Outperform at Wells Fargo and RBC Capital. 4. SI-Bone (SIBN) initiated with an Outperform at JMP Securities, an Overweight at Morgan Stanley, as well as a Buy at Canaccord and BofA/Merrill. 5. Studio City (MSC) initiated with an Underweight at Morgan Stanley. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
11/13/18
NEED
11/13/18
INITIATION
Target $18
NEED
Buy
PhaseBio initiated with a Buy at Needham
Needham analyst Chad Messer initiated PhaseBio (PHAS) with a Buy rating and a price target of $18, saying it poses an "attractive investment with a near term commercial opportunity from PB2452" - the closes to market threat to AstraZeneca's (AZN) Brilinta to treat orphan cardiopulmonary diseases. The analyst notes that the company is also evaluating PB1046, which is a "weekly injectable form of vasoactive intestinal peptide with a vastly increased half life over the natural form", for potential treatment of rare pulmonary arterial hypertension.
11/13/18
11/13/18
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Aerie Pharmaceuticals (AERI) initiated with an Outperform at Oppenheimer. 2. SolarWinds (SWI) initiated with a Buy at Nomura Instinet, SunTrust, Citi, and Goldman Sachs, an Outperform at RBC Capital, Baird, Credit Suisse, JMP Securities, and Evercore ISI, an Overweight at JPMorgan, an Equal Weight at Morgan Stanley and Barclays, as well as a Sector Weight at KeyBanc. 3. PhaseBio (PHAS) initiated with a Buy at Needham. 4. LogicBio Therapeutics (LOGC) initiated with an Overweight at Barclays, a Buy at Chardan, and an Outperform at William Blair. 5. Cree (CREE) initiated with an Outperform at BMO Capital. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

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Tanger Factory

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USAT

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-0.22 (-2.88%)

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USAT

USA Technologies

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USAT

USA Technologies

$7.43

-0.22 (-2.88%)

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FISV

Fiserv

$104.82

-0.03 (-0.03%)

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Fiserv call volume above normal and directionally bullish »

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TD

Toronto-Dominion

$57.97

0.4 (0.69%)

, DB

Deutsche Bank

$8.02

-0.055 (-0.68%)

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TD accepted Epstein accounts after Deutsche cut ties, Bloomberg says »

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TD

Toronto-Dominion

$57.97

0.4 (0.69%)

DB

Deutsche Bank

$8.02

-0.055 (-0.68%)

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  • 27

    Oct

IVV

iShares Core S&P 500

$301.93

-0.845 (-0.28%)

, SPY

SPDR S&P 500 ETF Trust

$298.77

-0.906381 (-0.30%)

14:22
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Technical Analysis
On The Fly: Weekly technical notes for S&P 500 »

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IVV

iShares Core S&P 500

$301.93

-0.845 (-0.28%)

SPY

SPDR S&P 500 ETF Trust

$298.77

-0.906381 (-0.30%)

HYG

iShares iBoxx $ High Yield Corporate Bond

$87.41

0.05 (0.06%)

IEF

iShares 7-10 Year Treasury Bond ETF

$111.69

0.335 (0.30%)

ITE

SPDR Bloomberg Barclays Intermediate Term Treasury ETF

$62.19

0.065 (0.10%)

SPTL

SPDR Portfolio Long Term Treasury ETF

$40.45

0.12 (0.30%)

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$NSD

NASDAQ Market Internals

$0.00

(0.00%)

14:17
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Technical Analysis
NASDAQ market internals summary »

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$NYE

NYSE Market Internals

$0.00

(0.00%)

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Technical Analysis
NYSE market internals summary »

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PDD

Pinduoduo

$33.65

-0.98 (-2.83%)

14:15
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14:15
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Options
Pinduoduo put volume heavy and directionally bearish »

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FIT

Fitbit

$4.00

0.3347 (9.13%)

14:11
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14:11
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14:11
Periodicals
Fitbit deciding whether to explore sale, Reuters says »

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FIT

Fitbit

$3.69

0.025 (0.68%)

14:07
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Hot Stocks
Fitbit rises after report of hiring bank to consider sale »

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FIT

Fitbit

$3.73

0.06 (1.64%)

14:03
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14:03
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Periodicals
Breaking Periodicals news story on Fitbit »

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W

Wayfair

$122.80

-5.865 (-4.56%)

13:55
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Options
Wayfair put volume heavy and directionally bearish »

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DELL

Dell Technologies

$52.26

-0.8 (-1.51%)

13:53
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Conference/Events
Dell Technologies to hold a business news update meeting »

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FTR

Frontier Communications

$1.00

-0.0006 (-0.06%)

13:43
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Periodicals
Frontier Communications prepares for debt restructuring talks, WSJ reports »

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13:40
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General news
U.S. equity markets »

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BTU

Peabody Energy

$15.47

-1.56 (-9.16%)

, ARCH

Arch Coal

$71.00

-5.37 (-7.03%)

13:39
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Hot Stocks
Peabody Energy confirms commitment to pending PRB/Colorado joint venture »

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BTU

Peabody Energy

$15.47

-1.56 (-9.16%)

ARCH

Arch Coal

$71.00

-5.37 (-7.03%)

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  • 23

    Sep

SPY

SPDR S&P 500 ETF Trust

$298.09

-1.586381 (-0.53%)

, SPX

S&P 500

$0.00

(0.00%)

13:34
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13:34
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13:34
Periodicals
Chinese delgation cancels farm trip to Montana, Reuters reports »

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SPY

SPDR S&P 500 ETF Trust

$298.09

-1.586381 (-0.53%)

SPX

S&P 500

$0.00

(0.00%)

DJX

Dow Jones Industrial Average

$0.00

(0.00%)

NDX

Nasdaq 100 Index

$0.00

(0.00%)

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RACE

Ferrari

$151.80

-1.95 (-1.27%)

13:30
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Options
Trader trims risk by legging out of iron condor in Ferrari »

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MGM

MGM Resorts

$29.05

-0.01 (-0.03%)

13:25
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13:25
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Options
MGM Resorts call volume above normal and directionally bullish »

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SPY

SPDR S&P 500 ETF Trust

$300.00

0.323619 (0.11%)

, SPX

S&P 500

$0.00

(0.00%)

13:22
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General news
Breaking General news story on SPDR S&P 500 ETF Trust, S&P 500 »

Montana farm bureau says…

SPY

SPDR S&P 500 ETF Trust

$300.00

0.323619 (0.11%)

SPX

S&P 500

$0.00

(0.00%)

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