Breaking News Instant updates and real-time market news.

DARE

Dare Bioscience

$0.79

0.0013 (0.16%)

08:08
09/11/19
09/11
08:08
09/11/19
08:08

Dare Bioscience announces publication of pharmacokinetics study of DARE-VVA1

Dare Bioscience announced the article entitled "Vaginal tamoxifen for treatment of vulvar and vaginal atrophy: Pharmacokinetics and local tolerance in a rabbit model over 28 days" was published online in the International Journal of Pharmaceutics. The article highlights the positive findings from the animal study which include availability and local tolerability of vaginally delivered tamoxifen. DARE-VVA1 is a novel vaginal application of tamoxifen, the well-known and well-characterized selective estrogen receptor modulator, and is being developed by Dare as an alternative to estrogen-based therapies for the treatment of vulvar and vaginal atrophy in women with or at risk for hormone-receptor positive (HR+) breast cancer. In breast tissue, tamoxifen acts as an estrogen antagonist, while in other tissue, including vaginal tissue, tamoxifen has been reported to exert an estrogen-like response on vaginal cytology. The goal of the study was to evaluate tamoxifen at two dose levels administered intra-vaginally to female rabbits once-daily over a 28-day period to assess its pharmacokinetics, systemic exposure and local vaginal tolerance. The findings revealed that there was little to no vaginal or systemic accumulation of tamoxifen following once-daily dosing for 28 days and that vaginal irritation was minimal to none at both doses.VVA is an inflammation of the vaginal epithelium due to the reduction in levels of circulating estrogen. Commonly used therapies for VVA are estrogen-based and often contraindicated in HR+ breast cancer patients, or patients with a genetic predisposition or history of familial disease, because of the concern that estrogen use will promote recurrence of disease. Many breast cancer survivors experience menopausal symptoms as a direct consequence of cancer treatment. Breast cancer patients treated with aromatase inhibitors refer to VVA as one of the most unpleasant side effects of treatment. A prior study of DARE-VVA1 published in Clinical and Experimental Obstetrics and Gynecology, demonstrated that weekly vaginal administration of tamoxifen for three months in post-menopausal women with VVA showed improvements in vaginal pH and vaginal dryness without significant systemic absorption of tamoxifen.

DARE Dare Bioscience
$0.79

0.0013 (0.16%)

08/22/19
AGIS
08/22/19
INITIATION
Target $3
AGIS
Buy
Dare Bioscience initiated with a Buy at Aegis
Aegis analyst Nathan Weinstein initiated Dare Bioscience with a Buy rating and $3 price target.

TODAY'S FREE FLY STORIES

PNRL

Paringa Resources

$2.28

-0.06 (-2.56%)

20:18
09/16/19
09/16
20:18
09/16/19
20:18
Hot Stocks
Paringa Resources names Jim Middleton as Executive Advisor »

Paringa Resources is…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

RBNC

Reliant Bancorp

$24.70

0.16 (0.65%)

20:17
09/16/19
09/16
20:17
09/16/19
20:17
Hot Stocks
Reliant Bancorp to buy Tennessee Community Bank Holdings for $37.2M »

Reliant Bancorp announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Sep

ORCL

Oracle

$53.12

-0.64 (-1.19%)

, INTC

Intel

$52.21

-0.32 (-0.61%)

19:12
09/16/19
09/16
19:12
09/16/19
19:12
Hot Stocks
Intel, Oracle collaborate on Optane DC Persistent Memory »

Intel (INTC) and Oracle…

ORCL

Oracle

$53.12

-0.64 (-1.19%)

INTC

Intel

$52.21

-0.32 (-0.61%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 24

    Oct

ORCL

Oracle

$53.12

-0.64 (-1.19%)

, VMW

VMware

$155.87

4.81 (3.18%)

19:08
09/16/19
09/16
19:08
09/16/19
19:08
Hot Stocks
VMware, Oracle expand partnership on hybrid cloud »

Oracle (ORCL) and VMware…

ORCL

Oracle

$53.12

-0.64 (-1.19%)

VMW

VMware

$155.87

4.81 (3.18%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 10

    Oct

ACRS

Aclaris Therapeutics

$1.09

0.06 (5.83%)

, BBCP

Concrete Pumping

$4.40

0.265 (6.41%)

19:05
09/16/19
09/16
19:05
09/16/19
19:05
Hot Stocks
Fly Intel: After Hours Movers »

HIGHER: Aclaris…

ACRS

Aclaris Therapeutics

$1.09

0.06 (5.83%)

BBCP

Concrete Pumping

$4.40

0.265 (6.41%)

GLW

Corning

$30.04

-0.12 (-0.40%)

XLRN

Acceleron

$44.67

0.75 (1.71%)

SHOP

Shopify

$337.93

-0.77 (-0.23%)

KHC

Kraft Heinz

$29.62

0.37 (1.27%)

PSTV

Plus Therapeutics

$9.51

-0.05 (-0.52%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 16

    Sep

  • 18

    Sep

  • 01

    Oct

  • 17

    Oct

  • 17

    Oct

  • 04

    Dec

  • 04

    Apr

  • 17

    Sep

KHC

Kraft Heinz

$29.62

0.37 (1.27%)

19:03
09/16/19
09/16
19:03
09/16/19
19:03
Hot Stocks
3G Capital sells 25.1M shares of Kraft Heinz »

In a regulatory filing,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    Oct

KHC

Kraft Heinz

$29.62

0.37 (1.27%)

18:53
09/16/19
09/16
18:53
09/16/19
18:53
Hot Stocks
Kraft Heinz's Lemann acquires nearly 3.5M common shares »

In a regulatory filing,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    Oct

HMSY

HMS Holdings

$37.14

0.24 (0.65%)

18:43
09/16/19
09/16
18:43
09/16/19
18:43
Hot Stocks
HMS Holdings acquires VitreosHealth for approximately $36.5M »

HMS Holdings announced it…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

18:25
09/16/19
09/16
18:25
09/16/19
18:25
General news
U.S. industrial production preview: »

U.S. industrial…

18:25
09/16/19
09/16
18:25
09/16/19
18:25
General news
Treasury Market Summary »

Treasury Market Summary:…

ICAD

iCAD

$6.89

-0.01 (-0.14%)

18:25
09/16/19
09/16
18:25
09/16/19
18:25
Conference/Events
iCAD to hold an investor reception »

Management hosts "An…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 16

    Sep

  • 12

    Nov

GLW

Corning

$30.04

-0.12 (-0.40%)

18:18
09/16/19
09/16
18:18
09/16/19
18:18
Hot Stocks
Corning down 5.5% or $1.64 at $28.40 per share after cutting volume outlook »

As part of the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

WE

We Company

$0.00

(0.00%)

18:17
09/16/19
09/16
18:17
09/16/19
18:17
Periodicals
We Company IPO delayed until October at earliest, WSJ reports »

The We Company's IPO…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

GLW

Corning

$30.04

-0.12 (-0.40%)

18:16
09/16/19
09/16
18:16
09/16/19
18:16
Hot Stocks
Corning cuts Q3 volume guidance for Display and Optical Communications units »

Corning is providing the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

WE

We Company

$0.00

(0.00%)

18:05
09/16/19
09/16
18:05
09/16/19
18:05
Periodicals
Breaking Periodicals news story on We Company »

We Company IPO delayed…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

GM

General Motors

$37.21

-1.62 (-4.17%)

18:02
09/16/19
09/16
18:02
09/16/19
18:02
Periodicals
Auto workers strike could cost GM $100M daily, WSJ says »

General Motors could lose…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

HLNE

Hamilton Lane

$59.95

-0.51 (-0.84%)

17:57
09/16/19
09/16
17:57
09/16/19
17:57
Hot Stocks
Hamilton Lane vice chairman sells 150K shares of common stock »

In a regulatory filing,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

17:52
09/16/19
09/16
17:52
09/16/19
17:52
Conference/Events
SVB Leerink biotech analysts to hold analyst/industry conference call »

Biotech Analysts discuss…

HLNE

Hamilton Lane

$59.95

-0.51 (-0.84%)

17:52
09/16/19
09/16
17:52
09/16/19
17:52
Hot Stocks
Hamilton Lane chairman sells 78.5K shares of common »

In a regulatory filing,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

GD

General Dynamics

$190.91

0.98 (0.52%)

, BAH

Booz Allen

$70.35

0.85 (1.22%)

17:44
09/16/19
09/16
17:44
09/16/19
17:44
Hot Stocks
General Dynamics, Booz Allen and Parsons awarded $427M max Air Force contract »

General Dynamics (GD),…

GD

General Dynamics

$190.91

0.98 (0.52%)

BAH

Booz Allen

$70.35

0.85 (1.22%)

PSN

Parsons

$37.25

0.35 (0.95%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Oct

T

AT&T

$37.32

-0.58 (-1.53%)

17:43
09/16/19
09/16
17:43
09/16/19
17:43
Periodicals
Suit claims AT&T told employees to make fake DirecTV accounts, Bloomberg says »

According to a lawsuit…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Oct

UBER

Uber

$34.42

1.18 (3.55%)

, LYFT

Lyft

$47.78

1.68 (3.64%)

17:39
09/16/19
09/16
17:39
09/16/19
17:39
Periodicals
Uber to limit drivers' app access in NYC to comply with rules, Reuters says »

Uber (UBER) on Tuesday…

UBER

Uber

$34.42

1.18 (3.55%)

LYFT

Lyft

$47.78

1.68 (3.64%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

NEE

NextEra Energy

$218.31

-0.19 (-0.09%)

17:36
09/16/19
09/16
17:36
09/16/19
17:36
Conference/Events
NextEra Energy management to meet with UBS »

Meeting to be held in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Sep

  • 02

    Oct

  • 10

    Nov

  • 10

    Nov

NJR

New Jersey Resources

$44.80

-0.36 (-0.80%)

17:34
09/16/19
09/16
17:34
09/16/19
17:34
Hot Stocks
New Jersey Resources formally appoints Steve Westhoven CEO »

Following New Jersey…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

MEGEF

MEG Energy

$0.00

(0.00%)

17:34
09/16/19
09/16
17:34
09/16/19
17:34
Conference/Events
MEG Energy management to meet with UBS »

Meeting to be held in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Sep

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.