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QBIO

Q BioMed

$0.00

(0.00%)

11:12
09/11/19
09/11
11:12
09/11/19
11:12

Q BioMed, Chemveda enter agreement for synthesis of chemotherapeutic

Q BioMed and Chemveda Life Sciences announce that after the recent chemical synthesis of a unique natural compound that has shown remarkable efficacy as a potential chemotherapy for the treatment of liver cancer, the two companies have formalized a collaboration to continue the work and to scale-up manufacturing of cGMP product for planned pre-clinical testing and clinical trials. Since February 2017, Q BioMed and Chemveda have been engaged in a joint research program to synthesize uttroside B and several other derivatives. The goal of the program is to study their potential use in clinical trials for the treatment of hepatocellular carcinoma as well as other cancers. In a Scientific Reports study, researchers showed that in animal models, uttroside B was ten times more cytotoxic to the HepG2 liver cancer cell line than sorafenib, the only drug approved by the Food and Drug Administration for liver cancer at the time and the current first line treatment for hepatocellular carcinoma. Uttroside B drastically reduced tumors in mice bearing human liver cancer xenografts. In addition, in pre-clinical experiments, uttroside B induced cytotoxicity in all liver cancer cell lines and researchers were able to confirm its biological safety, both by in vitro and in vivo studies. Q BioMed is awaiting confirmatory cell line efficacy data from the synthesized drug product and its derivatives. Under the Agreement and depending upon reaching certain milestones, Q BioMed have agreed to pay Chemveda a combination of cash and stock and capped royalty on net sales of any and all drug product resulting from the collaboration. Subject to the terms of the Agreement, Chemveda shall have the first right of refusal and, if exercised, the exclusive right to manufacture any products developed as a result of the program for pre-commercial and commercial production.

QBIO Q BioMed
$0.00

(0.00%)

11/29/18
ROTH
11/29/18
DOWNGRADE
Target $1.85
ROTH
Neutral
Q BioMed downgraded to Neutral from Buy at Roth Capital
Roth Capital analyst Scott Henry downgraded Q BioMed to Neutral and lowered his price target for the shares to $1.85 from $6.75. The acquisition of Metastron is a positive given that Q BioMed will now own the market, but this is more than offset by the market having contracted beyond expectations, Henry tells investors in a research note. The analyst views the company's risk profile as elevated "given the need to rebuild the market with limited financial resources."

TODAY'S FREE FLY STORIES

AMED

Amedisys

$130.73

-2.13 (-1.60%)

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HLM

Hillman Companies

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ACRS

Aclaris Therapeutics

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ALDR

Alder Biopharmaceuticals

$18.50

8.45 (84.08%)

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XON

Intrexon

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0.44 (6.85%)

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SHOP

Shopify

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KTOV

Kitov Pharmaceuticals

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DRQ

Dril-Quip

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WOW

WideOpenWest

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0.325 (5.49%)

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XLRN

Acceleron

$44.67

0.75 (1.71%)

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DMTK

DermTech

$5.80

-0.18 (-3.01%)

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LDOS

Leidos

$86.22

0.38 (0.44%)

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SAIC

SAIC

$83.81

-0.39 (-0.46%)

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EHC

Encompass Health

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SEM

Select Medical

$16.97

0.01 (0.06%)

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AMED

Amedisys

$130.73

-2.13 (-1.60%)

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Options
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CME

CME Group

$207.01

1.26 (0.61%)

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PBH

Prestige Brands

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CBOE

Cboe Global Markets

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FNKO

Funko

$27.86

0.47 (1.72%)

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CURO

Curo Group

$15.28

-0.045 (-0.29%)

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ICE

IntercontinentalExchange

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1.05 (1.16%)

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CME

CME Group

$207.01

1.26 (0.61%)

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USB

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-0.21 (-0.37%)

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