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RHHBY

Roche

$0.00

(0.00%)

05:27
09/12/19
09/12
05:27
09/12/19
05:27

Genentech says satralizumab 'significantly' reduced relapse risk in second study

Genentech, a member of the Roche Group, presented full pivotal Phase III study results for satralizumab as a monotherapy for neuromyelitis optica spectrum disorder, or NMOSD, a rare, debilitating central nervous system disease. Results from the SAkuraStar study, presented at the 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis, or ECTRIMS, show that satralizumab monotherapy achieved a 55% reduction in the risk of relapses compared to placebo in the overall population, representative of NMOSD patients. In the large subgroup of patients seropositive for AQP4-IgG antibodies, the effect was higher with a 74% reduction in risk of relapses. People who are AQP4-IgG seropositive tend to experience a more severe disease course. "The positive Phase III results for satralizumab, first as an add-on therapy and now as a monotherapy, are exciting to see, and importantly, satralizumab achieved efficacy in a broad range of NMOSD patients, reflective of what we see in our everyday practice. Satralizumab targets the IL-6 receptor, potentially offering a novel treatment approach," said Professor Jeffrey Bennett, University of Colorado Neurology & Ophthalmology. "Approved treatment options demonstrating favorable safety and efficacy in controlled clinical trials are urgently needed. Even one relapse may lead to blindness and debilitating motor dysfunction for people with NMOSD."

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RHHBY Roche
$0.00

(0.00%)

07/17/19
RAJA
07/17/19
NO CHANGE
RAJA
Investors shouldn't overreact to drug proposal headlines, says Raymond James
Raymond James analyst Chris Meekins noted that President Donald Trump has indicated an Executive Order on drug pricing is coming soon, but he believes investors "should be cautious not to overreact" to drug related proposal headlines as he "cannot think of a single proposal that was finalized and also survived a court challenge resulting in a negative impact on earnings" yet from the Trump Administration. Given the history of the current White House to date, Meekins said he is increasingly skeptical the Administration will get anything meaningful finalized and overcome legal challenges that will impact drugmakers' earnings before the 2020 election, he tells investors in a healthcare policy note. Publicly traded large cap drugmakers include AstraZeneca (AZN), Bristol-Myers (BMY), Eli Lilly (LLY), GlaxoSmithKline (GSK), Johnson & Johnson (JNJ), Merck (MRK), Novartis (NVS), Pfizer (PFE), Roche (RHHBY) and Sanofi (SNY).
07/23/19
BTIG
07/23/19
INITIATION
Target $46
BTIG
Buy
Adaptive Biotechnologies initiated with a Buy at BTIG
BTIG analyst Amanda Murphy initiated Adaptive Biotechnologies (ADPT) with a Buy rating and a price target of $46, saying the company's "clinical immunomics database" represents its "differentiating asset" and offers "incredible value" to biopharma companies. The analyst further cites Adaptive Biotechnologies' partnership with Roche (RHHBY) that should allow it to develop new diagnostics for early detection of diseases where antigens are unknown and also its "strategic" deal with Microsoft (MSFT), whose machine learning capabilities support its immune medicine platform.
07/23/19
JPMS
07/23/19
NO CHANGE
JPMS
Neutral
Competition questions for Biogen, Ions' Spinraza not dissipating soon, says JPMorgan
Following Biogen's (BIIB) quarterly results, JPMorgan analyst Jessica Fye notes that while there seems to be limited second quarter impact to the company's and partner Ions Pharmaceuticals' (IONS) Spinraza from Novartis' (NVS) Zolgensma international revenues were down quarter over quarter for a variety of reasons despite double-digit patient growth. Overall, the analyst maintains her view that Roche (RHHBY) and PTC Therapeutics' (PTCT) Risdiplam represents a key potential competitive threat to Spinraza given the convenience of oral dosing and with filing for Risdiplam anticipated in the second half of 2019, in addition to Zolgensma's launch, Fye does not see questions related to competition for Spinraza dissipating anytime soon. The analyst reiterates a Neutral rating on Ions Pharmaceuticals' shares.
07/26/19
UBSW
07/26/19
UPGRADE
UBSW
Buy
Roche upgraded to Buy from Neutral at UBS
UBS analyst Michael Leuchten upgraded Roche to Buy from Neutral and raised his price target for the shares to CHF 300 from CHF 270. The company's legacy portfolio, built around Herceptin and Rituxan, is showing greater resilience while its "credible" neuroscience pipeline is taking shape, Leuchten tells investors in a research note. As such, he now sees Roche's business model as less challenged.

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Institute of International Finance to hold annual meeting »

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S&P Global

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STT

State Street

$63.40

3.69 (6.18%)

20:09
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Upgrade
State Street rating change at Keefe Bruyette »

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SUN

Sunoco

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0.32 (1.00%)

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Sunoco rating change at BMO Capital »

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TLF

Tandy Leather

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AAPL

Apple

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JPM

JPMorgan

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0.21 (0.17%)

, FB

Facebook

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-4.435 (-2.33%)

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JPMorgan CEO says Libra 'a neat idea that will never happen,' Reuters says »

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JPMorgan

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FB

Facebook

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PYPL

PayPal

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MA

MasterCard

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Visa

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EBAY

eBay

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BKNG

Booking Holdings

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GLD

SPDR Gold Shares

$140.47

-0.13 (-0.09%)

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TECK

Teck Resources

$16.48

0.11 (0.67%)

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OSK

Oshkosh

$77.22

0.46 (0.60%)

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OVLY

Oak Valley Bancorp

$16.40

-0.16 (-0.97%)

17:35
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Earnings
Oak Valley Bancorp reports Q3 EPS 40c vs. 37c last year »

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FTNW

FTE Networks

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TNXP

Tonix Pharmaceuticals

$0.45

0.0048 (1.07%)

17:12
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Breaking Syndicate news story on Tonix Pharmaceuticals »

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RLMD

Relmada Therapeutics

$20.18

1.07 (5.60%)

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Breaking General news story  »

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NWSA

News Corp.

$13.48

-0.19 (-1.39%)

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News Corp

$13.79

-0.11 (-0.79%)

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Facebook reaches pact with News Corp., others for news section, WSJ says »

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FB

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NYT

New York Times

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WAIR

Wesco Aircraft

$11.01

0.01 (0.09%)

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Wesco Aircraft to host special shareholder meeting »

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FOMX

Foamix

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Breaking Hot Stocks news story on Foamix »

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POAI

Predictive Oncology

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0.0101 (2.35%)

16:40
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BK

BNY Mellon

$45.34

0.975 (2.20%)

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BNY Mellon SVP Harris sells 50K shares of common stock »

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BAC

Bank of America

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0.1 (0.33%)

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Bank of America's Knox sells 40,000 common shares »

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LGC

Legacy Acquisition Corp

$10.24

0.02 (0.20%)

16:34
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Legacy Acquisition Corp to host special shareholder meeting »

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MFGP

Micro Focus

$15.13

0.56 (3.84%)

, OTEX

OpenText

$39.30

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Micro Focus

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OTEX

OpenText

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