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TOCA

Tocagen

$4.16

0.395 (10.51%)

06:02
09/12/19
09/12
06:02
09/12/19
06:02

Tocagen says Toca 5 Phase 3 clinical trial missed primary endpoint

Tocagen announced that the Toca 5 Phase 3, randomized, multi-center clinical trial evaluating Toca 511 & Toca FC in patients with recurrent high grade glioma, or HGG, undergoing resection missed the primary endpoint of overall survival compared to standard of care treatment. In addition, all secondary endpoints showed no meaningful difference between the arms of the trial. The safety, tolerability and adverse event profile of Toca 511 & Toca FC was as expected for this patient population. Further analysis of the Toca 5 trial data is currently underway and presentation of the results is planned at an upcoming medical conference.

TOCA Tocagen
$4.16

0.395 (10.51%)

04/26/19
04/26/19
INITIATION

Fly Intel: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Vail Resorts (MTN) initiated with a Buy at SunTrust. 2. Tocagen (TOCA) initiated with an Overweight at Cantor Fitzgerald. 3. Dow Inc. (DOW) initiated with a Hold at Argus. 4. Gilead (GILD) initiated with an Outperform at Bernstein. 5. Reed's (REED) initiated with a Buy at Lake Street. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
05/22/19
CANT
05/22/19
NO CHANGE
Target $28
CANT
Overweight
Tocagen dismissive views present 'strong opportunity,' says Cantor Fitzgerald
Cantor Fitzgerald analyst Elemer Piros reiterates an Overweight rating on Tocagen with a $28 price target after the company announced that the Phase 3 trial of Toca 511 and Toca FC in recurrent high-grade glioma will continue without modification. The analyst had always assumed that the most likely scenario would be that the trial would continue until the final interim analysis in Q4 or 2019. Any dismissive views on Tocagen present a "strong opportunity" ahead of the year-end catalyst, Piros tells investors in a research note. He continues to believe that positive survival data will favor Toca 511 and Toca FC versus chemotherapy.
05/22/19
LEER
05/22/19
NO CHANGE
Target $5
LEER
Market Perform
SVB Leerink says Tocagen trial failure likely, cuts target to $5 from $11
SVB Leerink analyst Daina Graybosch lowered her price target for Tocagen to $5 from $11 saying the Independent Data Monitoring Committee's recommendation to continue TOCA 5 trial aligns with her base case. A study failure announcement by year end is now likely, Graybosch tells investors in a research note. She believes the IDMC's recommendation to continue the study "has definitive negative read-through to a final outcome." The analyst keeps a Market Perform rating on Tocagen shares. The stock in premarket trading is down 27% to $6.45.
05/30/19
SBSH
05/30/19
INITIATION
Target $20
SBSH
Buy
Tocagen assumed with a Buy at Citi
Citi analyst Mohit Bansal assumed coverage of Tocagen with a Buy rating and $24 price target. Under a prior analyst, Citi had a Buy rating on the shares with a $27 price target.

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