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GH

Guardant Health

$62.57

-0.93 (-1.46%)

15:58
09/29/19
09/29
15:58
09/29/19
15:58

Guardant Health presents data from Phase II TRIUMPH trial

Guardant Health and the National Cancer Center Hospital East present data at the European Society of Medical Oncology conference from a prospective, multi-center phase II clinical trial, TRIUMPH. The study showed that patients with metastatic colorectal cancer with a HER2 amplification detected by the Guardant360 assay experienced clinical benefit from National Comprehensive Cancer Network guideline-recommended HER2-directed combination therapy. The study included patients with RAS-wild-type mCRC refractory to standard EGFR-directed therapies, and HER2 amplification detected using standard tissue-based testing or Guardant360. An interim analysis, led by principal investigators from the National Cancer Center Hospital East in Japan, demonstrated that mCRC patients with HER2 amplification detected by Guardant360 and treated with HER2-directed combination therapy achieved an objective response rate of 33.3%. Excluding patients with known markers of resistance detected by Guardant360, the ORR was 45.5%. The overall median progression-free survival was 4.0 months, and the median duration of response was 4.2 months. Importantly, patients with HER2-amplified tumors who also had Guardant360-detected mutations in KRAS, NRAS, PIK3CA or HER2 had much poorer responses and shorter PFS. In contrast, median PFS was 5.6 months when mutations in these genes were not detected by Guardant360.

GH Guardant Health
$62.57

-0.93 (-1.46%)

08/07/19
JPMS
08/07/19
NO CHANGE
Target $135
JPMS
Overweight
Guardant Health price target raised to $135 from $90 at JPMorgan
JPMorgan analyst Tycho Peterson raised his price target for Guardant Health to $135 from $90 saying the company last night reported "extremely strong" Q2 results. The quarter saw "robust" clinical testing momentum coupled with upside from biopharma and development services, Peterson tells investors in a research note. He continues to view Guardant as a "best-in-class asset in the attractive liquid biopsy space" and reiterates an Overweight rating on the shares.
08/07/19
ADAM
08/07/19
NO CHANGE
Target $125
ADAM
Buy
Guardant Health price target raised to $125 from $96 at Canaccord
Canaccord analyst Mark Massaro raised his price target on Guardant Health to $125 from $96 following a monster Q2 beat and raise quarter. In addition to its solid revenue growth, gross margins surged. The analyst said he likes the company's long-term strategic thinking, execution, and global vision across cancers in late stage therapy selection, cancer monitoring, and early-stage cancer screening. Massaro reiterated his Buy rating on Guardant Health shares.
09/11/19
ADAM
09/11/19
NO CHANGE
Target $125
ADAM
Buy
Guardant Health should be bought on weakness, says Canaccord
In an earlier research note to investors, Canaccord analyst Mark Massaro reiterated a Buy rating and $125 price on Guardant Health shares, and noted that he met with Guardant Health co-founder and CEO Helmy Eltoukhy and CFO Derek Bertocci. The analyst says the CEO touted innovation, risk-taking, and TAM expansion, and indicated that the analyst's $120B global TAM estimate for Guardant is "not far off." Further, as the company launches new franchises, it sees geometric increases in available market size, and overlapping growth cycles for many years to come, the analyst adds. Despite some recent weakness in shares, Massaro would be a buyer on the dip.
09/12/19
LEER
09/12/19
NO CHANGE
Target $130
LEER
Outperform
Guardant Health recent weakness a buying opportunity, says SVB Leerink
SVB Leerink analyst Puneet Souda views Guardant Health as a best-in-class liquid biopsy opportunity in a massive high growth market, with the company generating a conservative 60% revenue CAGR that is likely to accelerate as the overall LBx market grows. The analyst highlights buying opportunity amid recent weakness, and reiterates an Outperform rating and $130 price target on the shares given the catalyst path ahead over the next year.

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FTNW

FTE Networks

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TNXP

Tonix Pharmaceuticals

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RLMD

Relmada Therapeutics

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1.07 (5.60%)

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-0.19 (-1.39%)

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News Corp

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-0.11 (-0.79%)

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-4.435 (-2.33%)

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0.21 (0.71%)

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WAIR

Wesco Aircraft

$11.01

0.01 (0.09%)

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