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RHHBY

Roche

$0.00

(0.00%)

10:32
09/30/19
09/30
10:32
09/30/19
10:32

Genentech says Tecentriq, chemotherapy shows improvement in PFS in trial

Genentech, a member of the Roche Group, presented results from the Phase III IMvigor130 study evaluating Tecentriq plus platinum-based chemotherapy versus chemotherapy alone for the first-line treatment of people with previously untreated locally advanced or metastatic urothelial carcinoma eligible and ineligible for cisplatin chemotherapy. In the study, Tecentriq plus chemotherapy showed a statistically significant improvement in progression-free survival compared with platinum-based chemotherapy alone. Encouraging overall survival results were observed for Tecentriq plus chemotherapy compared with chemotherapy alone in the intention-to-treat population, however these data did not reach statistical significance at this interim analysis. Safety in the Tecentriq plus chemotherapy arm appeared consistent with the known safety profiles of the individual medicines, and no new safety signals were identified with the combination. "We are pleased with these positive results from the IMvigor130 study, which show Tecentriq plus chemotherapy may provide a meaningful benefit for people newly diagnosed with advanced bladder cancer," said Sandra Horning, M.D., chief medical officer and head of Global Product Development. "There remains a high unmet need for people with advanced bladder cancer, where chemotherapy alone is the current standard of care. These results reinforce the role of immunotherapy in treating this aggressive disease."

  • 04

    Nov

RHHBY Roche
$0.00

(0.00%)

07/23/19
JPMS
07/23/19
NO CHANGE
JPMS
Neutral
Competition questions for Biogen, Ions' Spinraza not dissipating soon, says JPMorgan
Following Biogen's (BIIB) quarterly results, JPMorgan analyst Jessica Fye notes that while there seems to be limited second quarter impact to the company's and partner Ions Pharmaceuticals' (IONS) Spinraza from Novartis' (NVS) Zolgensma international revenues were down quarter over quarter for a variety of reasons despite double-digit patient growth. Overall, the analyst maintains her view that Roche (RHHBY) and PTC Therapeutics' (PTCT) Risdiplam represents a key potential competitive threat to Spinraza given the convenience of oral dosing and with filing for Risdiplam anticipated in the second half of 2019, in addition to Zolgensma's launch, Fye does not see questions related to competition for Spinraza dissipating anytime soon. The analyst reiterates a Neutral rating on Ions Pharmaceuticals' shares.
07/26/19
UBSW
07/26/19
UPGRADE
UBSW
Buy
Roche upgraded to Buy from Neutral at UBS
UBS analyst Michael Leuchten upgraded Roche to Buy from Neutral and raised his price target for the shares to CHF 300 from CHF 270. The company's legacy portfolio, built around Herceptin and Rituxan, is showing greater resilience while its "credible" neuroscience pipeline is taking shape, Leuchten tells investors in a research note. As such, he now sees Roche's business model as less challenged.
09/13/19
DBAB
09/13/19
NO CHANGE
DBAB
Hold
Novartis' ofatumumab to be 'strong' competitor to Roche drug, says Deutsche Bank
Deutsche Bank analyst Richard Parkes tells investors in a research note after attending the ECTRIMS conference in Stockholm that data from Novartis' (NVS) ASCLEPIOS trials suggests ofatumumab will be a "strong" competitor for Roche's (RHHBY) Ocrevus in relapsing/remitting multiple sclerosis. Parkes says he expects physicians to view the drugs as having broadly comparable and highly compelling efficacy, with ofatumumab's at-home dosing an attractive option for some patients, suggesting meaningful upside potential to his current 2024E ofatumumab sales of $1.1B and possible risks to his forecasts for Roche's Ocrevus. According to physician feedback, Parkes says the drugs are likely to share a rapidly growing market. Parkes maintains a Hold rating and 90 CHF price target on Novartis shares.
09/23/19
GUGG
09/23/19
UPGRADE
Target $403
GUGG
Buy
Guggenheim upgrades Regeneron to Buy, says sentiment too negative
As previously reported, Guggenheim upgraded Regeneron (REGN) to Buy from Neutral as analyst Yatin Suneja noted that Eylea has maintained its dominance in the branded anti-VEGF retinal disease market despite "stiff branded competition" from Roche's (RHHBY) Lucentis and off-label use of Roche's Avastin. Eylea's expansion into new indications has resulted in a diversified business and defensible market position, argued Suneja, who also believes the Street is substantially under-appreciating the market opportunity for Dupixent, which is expected to drive significant leverage in the Sanofi (SNY) antibody collaboration that recently became profitable. Suneja raised the price target on Regeneron shares to $403 from $355.

TODAY'S FREE FLY STORIES

HPQ

HP Inc.

$20.17

0.05 (0.25%)

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MDT

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BRK.A

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0.38 (0.17%)

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RCEL

Avita Medical

$8.13

-0.06 (-0.73%)

20:39
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EIDX

Eidos Therapeutics

$46.58

1.33 (2.94%)

20:37
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Recommendations
Eidos Therapeutics analyst commentary  »

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COO

Cooper Companies

$301.97

2.64 (0.88%)

20:30
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CRM

Salesforce

$163.20

0.18 (0.11%)

20:21
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20:21
Recommendations
Salesforce analyst commentary at Jefferies »

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  • 20

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CCMP

Cabot Microelectronics

$155.89

2.68 (1.75%)

20:15
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Earnings
Breaking Earnings news story on Cabot Microelectronics »

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  • 18

    Nov

CCMP

Cabot Microelectronics

$155.89

2.68 (1.75%)

20:15
11/17/19
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Earnings
Cabot Microelectronics sees Q1 total revenue approximately flat »

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  • 18

    Nov

CCMP

Cabot Microelectronics

$155.89

2.68 (1.75%)

20:14
11/17/19
11/17
20:14
11/17/19
20:14
Earnings
Cabot Microelectronics reports Q4 EPS $1.68, consensus $1.63 »

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  • 18

    Nov

JEF

Jefferies Financial Group

$19.08

0.16 (0.85%)

20:13
11/17/19
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NIO

NIO Inc.

$1.82

0.07 (4.01%)

20:11
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GOLD

Barrick Gold

$16.57

-0.095 (-0.57%)

20:09
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GOLD

Barrick Gold

$16.57

-0.095 (-0.57%)

15:40
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Periodicals
Saracen close to buying Barrick Gold mine stake for $750M, Bloomberg says »

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ESPR

Esperion

$40.51

0.67 (1.68%)

15:11
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    Feb

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PCG

PG&E

$7.41

0.71 (10.60%)

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PG&E monitoring potential weather event that could lead to power shutoffs »

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  • 07

    Jan

XRX

Xerox

$38.95

0.295 (0.76%)

, HPQ

HP Inc.

$20.17

0.05 (0.25%)

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XRX

Xerox

$38.95

0.295 (0.76%)

HPQ

HP Inc.

$20.17

0.05 (0.25%)

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  • 26

    Nov

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    Dec

FOX

Fox Corp.

$33.60

0.14 (0.42%)

, FOXA

Fox Corp.

$34.26

0.04 (0.12%)

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Box Office Battle: 'Ford v Ferrari' races to top, 'Charlie's Angels' disappoints »

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FOX

Fox Corp.

$33.60

0.14 (0.42%)

FOXA

Fox Corp.

$34.26

0.04 (0.12%)

LGF.A

Lionsgate

$9.67

0.315 (3.37%)

LGF.B

Lionsgate

$9.07

0.345 (3.96%)

SNE

Sony

$62.03

0.23 (0.37%)

VIA

Viacom

$26.59

1.28 (5.06%)

VIAB

Viacom

$23.07

0.59 (2.62%)

T.CA

TELUS Corp. (Toronto)

$0.00

(0.00%)

CMCSA

Comcast

$44.54

-0.93 (-2.05%)

CMCSK

Comcast

$0.00

(0.00%)

DIS

Disney

$144.63

-2.56 (-1.74%)

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  • 09

    Dec

JNJ

Johnson & Johnson

$134.97

3.99 (3.05%)

13:36
11/17/19
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J&J rushed to test baby powder and got complicated results, WSJ says »

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BA

Boeing

$371.55

4.25 (1.16%)

13:24
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Boeing 737 makes emergency landing after engine malfunction, NY Post says »

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AZN

AstraZeneca

$47.46

0.09 (0.19%)

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  • 18

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LLY

Eli Lilly

$113.18

1.8 (1.62%)

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  • 30

    Jan

AZN

AstraZeneca

$47.46

0.09 (0.19%)

13:09
11/17/19
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AstraZeneca says data shows Farxiga reduces risks in heart failure patients »

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  • 18

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BA

Boeing

$371.55

4.25 (1.16%)

13:05
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Boeing, Biman announce order for two 787-9 Dreamliner jets »

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BBIO

BridgeBio

$28.26

0.55 (1.98%)

, EIDX

Eidos Therapeutics

$46.58

1.33 (2.94%)

13:03
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BridgeBio, Eidos present 'positive' data from Phase 2 clinical trial of AG10 »

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BBIO

BridgeBio

$28.26

0.55 (1.98%)

EIDX

Eidos Therapeutics

$46.58

1.33 (2.94%)

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  • 18

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CLBS

Caladrius

$2.64

-0.06 (-2.22%)

13:01
11/17/19
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KNSA

Kiniksa

$6.52

0.1 (1.56%)

12:59
11/17/19
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Kiniksa presents Rilonacept final Phase 2 clinical data »

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