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ALPN

Alpine Immune Sciences

$2.86

-0.17 (-5.61%)

09:14
10/09/19
10/09
09:14
10/09/19
09:14

Alpine Immune Sciences management to meet with JMP Securities

Meeting to be held in Denver on October 15 hosted by JMP Securities.

  • 15

    Oct

ALPN Alpine Immune Sciences
$2.86

-0.17 (-5.61%)

12/02/18
PIPR
12/02/18
NO CHANGE
Target $12
PIPR
Overweight
Alpine Immune Sciences' ALPN-101 active in GvHD, CTA by YE18, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff notes that Alpine (ALPN) presented two posters at ASH on proprietary variable Immunoglobulin Domain technology. In vivo data at ASH showed single doses enhanced survival in GvHD models compared to Bristol Myer's (BMY) Nujolix, he notes, adding that a CTA for ALPN-101 by YE18 should enable healthy volunteer data and lead to a Phase II GvHD start next year. The analyst also points out that Alpine presented novel Transmembrane ImmuneModulatory Proteins that can be engineered into T cells to enhance response in immunosuppressive environments. Importantly these strategies differ from TIP technology partnered to Kite (GILD) and offer further partnering opportunity, Tenthoff contends. He reiterates an Overweight rating and $12 price target on Alpine's shares.
01/22/19
PIPR
01/22/19
NO CHANGE
Target $11
PIPR
Overweight
Alpine Immune Sciences target lowered to $11 placement dilution at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff lowered his price target for Alpine Immune Sciences to $11 from $12 to reflect dilition from the company's recent private placement. Alpine recently issued 4.7 million units at $5.37 comprised of one share and 0.39 warrants with a $12.74 strike price raising gross proceeds of $25.3M, Tenthoff tells investors in a research note. The analyst estimates Alpine now holds pro forma cash of $86M to advance its pipeline of proprietary variant Ig domains as novel immunotherapies. He reiterates an Overweight rating on the shares.
05/15/19
PIPR
05/15/19
NO CHANGE
Target $11
PIPR
Overweight
Piper sees broad partnership potential for Alpine after Adaptimmune deal
After Alpine Immune Sciences (ALPN) announced a partnership with Adaptimmune (ADAP) to incorporate its novel Transmembrane and Secreted Immunomodulatory Proteins, or TIPs and SIPs, into CAR-T cells, Piper Jaffray analyst Edward Tenthoff said he sees Alpine having broad potential to partner its TIPs and SIPs for next generation cellular therapies. The analyst, who noted that Alpine is also advancing a platform of novel variant Ig domains, or "vIgDs," to augment T-cell activation, keeps an Overweight rating and $11 price target on Alpine shares.
05/24/19
PIPR
05/24/19
NO CHANGE
Target $11
PIPR
Overweight
Alpine Immune Sciences Kite pact termination 'a win,' says Piper Jaffray
Last week's new collaboration and license agreement between Alpine Immune Sciences (ALPN) with Adaptimmune (ADAP) essentially replaced the old deal between Kite Pharma and Gilead (GILD), termination of which was announced in a regulatory filing earlier today and is driving Alpine shares lower, Piper Jaffray analyst Edward Tenthoff tells investors in a research note to investors. Tenthoff says he sees this as a win for Alpine, who received $2M upfront and is eligible for an additional $288M in milestones, adding that he is a buyer of Alpine Immune Sciences on today's weakness ahead of ALPN-101 safety and biomarker data this quarter. Tenthoff maintains an Overweight rating and $11 price target on Alpine Immune Sciences shares.

TODAY'S FREE FLY STORIES

BSMX

Santander Mexico

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0.165 (2.47%)

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ACB

Aurora Cannabis

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-0.045 (-1.21%)

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ZLAB

Zai Lab

$32.38

0.01 (0.03%)

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  • 14

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AMZN

Amazon.com

$1,730.79

11.115 (0.65%)

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F

Ford

$8.78

0.145 (1.68%)

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  • 23

    Oct

ACM

Aecom

$37.14

0.35 (0.95%)

, LPG

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$11.48

0.22 (1.95%)

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$37.14

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LYFT

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1.8 (4.78%)

WDC

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$58.36

1.09 (1.90%)

FLXN

Flexion

$13.37

0.125 (0.94%)

AMTD

TD Ameritrade

$35.27

0.78 (2.26%)

IPGP

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$136.12

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YNDX

Yandex

$29.95

-5.62 (-15.80%)

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Yandex analyst commentary  »

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  • 25

    Oct

AMCX

AMC Networks

$48.42

0.89 (1.87%)

09:19
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  • 31

    Oct

SPX

S&P 500

$0.00

(0.00%)

, VIX

Volatility Index S&P 500 Options

$0.00

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SPX

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$0.00

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AGN

Allergan

$169.06

1.255 (0.75%)

, ABBV

AbbVie

$73.66

1.39 (1.92%)

09:17
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$169.06

1.255 (0.75%)

ABBV

AbbVie

$73.66

1.39 (1.92%)

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  • 01

    Nov

TOL

Toll Brothers

$39.49

0.2 (0.51%)

09:16
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GBT

Global Blood Therapeutics

$46.49

0.61 (1.33%)

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  • 26

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AMGN

Amgen

$200.76

2.05 (1.03%)

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  • 29

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JAZZ

Jazz Pharmaceuticals

$118.61

0.62 (0.53%)

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PBI

Pitney Bowes

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  • 05

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INFY

Infosys

$10.97

-0.22 (-1.97%)

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  • 11

    Nov

ARGO

Argo Group

$67.34

1.4 (2.12%)

09:12
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ARW

Arrow Electronics

$74.22

1.095 (1.50%)

, TXN

Texas Instruments

$130.08

2.52 (1.98%)

09:11
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ARW

Arrow Electronics

$74.22

1.095 (1.50%)

TXN

Texas Instruments

$130.08

2.52 (1.98%)

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  • 22

    Oct

BKI

Black Knight

$61.68

0.39 (0.64%)

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  • 13

    Nov

UPS

UPS

$116.06

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  • 22

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HON

Honeywell

$163.52

2.63 (1.63%)

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  • 17

    Oct

OKTA

Okta

$116.19

1.65 (1.44%)

, PING

Ping Identity

$16.47

0.45 (2.81%)

09:09
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$116.19

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PING

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ZS

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CRWD

Crowdstrike

$60.24

-1.08 (-1.76%)

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  • 15

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