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ARVN

Arvinas

$19.41

3.01 (18.35%)

14:07
10/23/19
10/23
14:07
10/23/19
14:07

Arvinas spikes 17% after platform update including Protac trial data

Earlier today, Arvinas announced a platform data update that includes initial safety, tolerability, and pharmacokinetic data from the company's ongoing Phase 1 clinical trials of ARV-110 and ARV-471. The data, which show dose-proportional exposures of ARV-110 and that both ARV-110 and ARV-471 have been well tolerated, will be presented by Ian Taylor, Ph.D., Chief Scientific Officer at Arvinas, at the 2nd Targeted Protein Degradation Summit in Boston, MA. Dr. Taylor's presentation will be available on Arvinas' website this morning. "This is the first look at clinical data from our PROTAC platform and is an exciting milestone for both Arvinas and for the field of targeted protein degradation. We are seeing a favorable overall safety profile for both clinical programs to date, and dose-proportional exposures of ARV-110," said John Houston, Ph.D., Chief Executive Officer at Arvinas. "We are encouraged by these initial results as we work to create well tolerated therapies to treat serious diseases." Arvinas expects to next share clinical data from the Phase 1 dose escalation trial of ARV-110 in the first half of 2020 and from the Phase 1 dose escalation trial of ARV-471 in the second half of 2020. Arvinas is up almost 17% to $19.10 per share in afternoon trading on Wednesday

  • 23

    Oct

ARVN Arvinas
$19.41

3.01 (18.35%)

09/11/19
BMOC
09/11/19
INITIATION
Target $34
BMOC
Outperform
Arvinas initiated with an Outperform at BMO Capital
BMO Capital analyst George Farmer started Arvinas with an Outperform rating and $34 price target. The company's drug candidates are derived from the proteolysis-targeting chimera technology and have broad applications in multiple therapeutic areas, Farmer tells investors in a research note. He believes that if the Phase 1 results successfully recapitulate the "very impressive" preclinical data, the stock should exceed "way past" his price target on "de-risked promise of the overall PROTAC technology platform." However, if the results disappoint, the shares could be devalued by about 85%, Farmer cautions.
09/12/19
09/12/19
INITIATION

Fly Intel: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Peloton (PTON) initiated with a Neutral at DA Davidson. 2. Uber (UBER) initiated with a Hold due to valuation at Argus. 3. Carvana (CVNA) initiated with a Buy at Needham while CarGurus (CARG) and TrueCar (TRUE) initiated with a Hold. 4. Coupa Software (COUP) and Fiserv (FISV) initiated with a Buy at Canaccord. 5. Arvinas (ARVN) initiated with an Outperform at BMO Capital. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.
09/24/19
WEDB
09/24/19
INITIATION
Target $38
WEDB
Outperform
Arvinas initiated with an Outperform at Wedbush
Wedbush analyst Robert Driscoll initiated Arvinas with an Outperform rating and $38 price target.
09/25/19
09/25/19
INITIATION
Target $38

Outperform
Wedbush bullish on Arvinas, initiates with an Outperform
As previously reported, Wedbush analyst Robert Driscoll started coverage of Arvinas with an Outperform rating and $38 price target. The analyst notes that the company is developing its potentially transformational PROTAC platform that he believes provides striking advantages over traditional therapeutic modalities such as small molecules and antibodies. Arvinas is initially targeting androgen receptor in prostate cancer and the estrogen receptor in ER-positive/HER2-negative breast cancer, with Driscoll seeing a high likelihood of success in these indications. Further, he believes the value of the PROTAC platform is underappreciated given the opportunity to apply this technology to previously undruggable targets.

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