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TRVN

Trevena

$1.01

0.0339 (3.49%)

07:25
11/04/19
11/04
07:25
11/04/19
07:25

Trevena expects to report topline data from TRV250 PoC study in 2H20

The company said, "Initiated TRV250 acute migraine proof-of-concept study. This is a single-dose, double-blind, placebo-controlled study with an enrollment target of approximately 120 migraine patients in a validated nitroglycerin provocation migraine model. Patients will be randomized before receiving a continuous NTG infusion, followed by administration of a 20 mg subcutaneous dose of TRV250 or placebo. The primary objective of the study is to determine target engagement, which will be measured as a reduction of sustained NTG-induced headaches. This study will also evaluate the overall safety of TRV250 and its ability to reduce symptomatic anxiety. The Company anticipates reporting topline data from this study in the second half of 2020."

  • 04

    Nov

TRVN Trevena
$1.01

0.0339 (3.49%)

11/05/18
HCWC
11/05/18
DOWNGRADE
Target $0.75
HCWC
Neutral
Trevena downgraded to Neutral from Buy at H.C. Wainwright
H.C. Wainwright analyst Ed Arce downgraded Trevena to Neutral and lowered his price target for the shares to 75c from $3.00. Following the Complete Response Letter from the FDA on the new drug application for oliceridin, a second-pass PDUFA date is unlikely until early 2020, Arce tells investors in a research note. He believes the CRL "leaves several open questions."
05/31/19
HCWC
05/31/19
INITIATION
Target $3.5
HCWC
Buy
Trevena assumed with a Buy at H.C. Wainwright
H.C. Wainwright analyst Douglas Tsao assumed coverage of Trevena with a Buy rating and $3.50 price target. The analsut believes the questions raised in the Complete Response Letter appear manageable and that Olinvo has a "clear path to approval." He expects Trevena shares to move higher as the company addresses the items needed to bring Olinvo to market.
09/03/19
HCWC
09/03/19
NO CHANGE
HCWC
Trevena's oliceridine 'close to the finish line,' says H.C. Wainwright
H.C. Wainwright analyst Douglas Tsao maiontained a Buy rating and $3.50 price target on Trevena. The analyst noted that Trevena recently announced that it completed enrollment for its ongoing healthy volunteer QT study and remained on track to support topline data readout in Q4. Trevena also said that more than 20 of 30 subjects at that point had received the maximum daily dose of 27mg of oliceridine, a key FDA requirement for the trial. This gives Tsao "confidence that the trial should be successful."

TODAY'S FREE FLY STORIES

AMSSY

AMS AG

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AMSSY

AMS AG

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GPN

Global Payments

$175.07

0.43 (0.25%)

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PZZA

Papa John's

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PZZA

Papa John's

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  • 18

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CNP

CenterPoint Energy

$24.83

-0.29 (-1.15%)

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AMRH

AMERI Holdings

$1.98

-0.13 (-6.16%)

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STM

STMicroelectronics

$27.16

0.74 (2.80%)

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MNTA

Momenta

$16.84

1.13 (7.19%)

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  • 16

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NOK

Nokia

$3.58

0.11 (3.17%)

, TIAOF

Telecom Italia

$0.00

(0.00%)

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NOK

Nokia

$3.58

0.11 (3.17%)

TIAOF

Telecom Italia

$0.00

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AEIS

Advanced Energy

$69.48

2.17 (3.22%)

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  • 16

    Dec

BKNG

Booking Holdings

$1,948.89

22.44 (1.16%)

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BKYI

BIO-key

$0.57

-0.0305 (-5.08%)

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CI

Cigna

$193.52

1.695 (0.88%)

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  • 06

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COST

Costco

$297.50

2.28 (0.77%)

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  • 05

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EAST

Eastside Distilling

$2.91

-0.02 (-0.68%)

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CNHI

CNH Industrial

$10.73

0.215 (2.04%)

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RIO

Rio Tinto

$57.52

0.62 (1.09%)

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BPMC

Blueprint Medicines

$73.75

0.93 (1.28%)

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CHH

Choice Hotels

$101.43

1.32 (1.32%)

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ICPT

Intercept

$115.78

-3.55 (-2.97%)

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  • 26

    Mar

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