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PIRS

Pieris Pharmaceuticals

$3.93

0.19 (5.08%)

10:51
11/10/19
11/10
10:51
11/10/19
10:51

Pieris presents data from phase 1 dose-escalation monotherapy study of PRS-343

Pieris Pharmaceuticals announced the presentation of data from the phase 1 dose-escalation monotherapy study of PRS-343, a 4-1BB/HER2 bispecific for the treatment of HER2-positive solid tumors, in a late-breaking oral presentation at the Society for Immunotherapy of Cancer Annual Meeting. PRS-343 demonstrated single-agent anti-tumor activity, including partial responses, in heavily pre-treated patients across multiple HER2-positive tumors. Beyond demonstrating clinical benefit, PRS-343 showed a potent increase in CD8+ T cell numbers and proliferative index in the tumor microenvironment of responders, indicative of 4-1BB agonism on T cells. PRS-343 was safe and well tolerated at all doses and schedules tested. "The data presented today demonstrate PRS-343's potential to make a meaningful difference for patients with tumors that are difficult to treat with currently-available therapies," said Geoffrey Ku, medical oncologist at Memorial Sloan Kettering and the principal investigator for the PRS-343 monotherapy trial. "Beyond today's presentation, I look forward to sharing some of these case studies at Pieris' upcoming R&D day alongside emerging data from the study of PRS-343 in combination with atezolizumab."

  • 11

    Nov

  • 11

    Nov

PIRS Pieris Pharmaceuticals
$3.93

0.19 (5.08%)

05/13/19
BARD
05/13/19
INITIATION
Target $5
BARD
Outperform
Pieris Pharmaceuticals initiated with an Outperform at Baird
Baird analyst Madhu Kumar initiated Pieris Pharmaceuticals with an Outperform and $5 price target.
05/14/19
BARD
05/14/19
INITIATION
Target $5
BARD
Outperform
Pieris Pharmaceuticals initiated with an Outperform at Baird
Baird analyst Madhu Kumar initiated Pieris Pharmaceuticals with an Outperform rating and $5 price target, saying he believe's Pieris' anticalin platform has the potential to disrupt biologic therapies in the respiratory and oncology spaces. The analyst called out the company's Phase 1 single ascending dose results for anti-interleukin-4 receptor a Ac PRS060 as potentially validating the drug's utility in asthma and serve as a positive catalyst for shares.
07/29/19
WBLR
07/29/19
NO CHANGE
WBLR
Outperform
Updates 'very positive' for upcoming Pieris presentation, says William Blair
Pieris Pharmaceuticals (PIRS) will present Phase Ib safety and efficacy results with PRS-060, an inhaled IL-4R alpha inhibitor, at the upcoming European Respiratory Society International Congress, held September 28 through October 2, William Blair analyst Matt Phipps tells investors in a research note. The poster presentation to be presented on October 1 is titled, "Multiple ascending dose study of the inhaled IL-4Ra antagonist, AZD1402/PRS-060, in mild asthmatics demonstrates robust FeNO reduction and a promising clinical profile for the treatment of asthma," the analyst point out. In addition, AstraZeneca (AZN) plans to initiate a Phase II trial with AZD1402/PRS-060 in the second half of this year, according to its recent earnings presentation, adds Phipps. He views these updates as "very positive" for the upcoming presentation, and believes PRS-060 has "significant potential" in the treatment of asthma patients. Phipps keeps an Outperform rating on Pieris Pharmaceuticals.
07/30/19
BARD
07/30/19
DOWNGRADE
Target $5
BARD
Neutral
Pieris Pharmaceuticals downgraded to Neutral from Outperform at Baird
Baird analyst Madhu Kumar downgraded Pieris Pharmaceuticals to Neutral from Outperform with an unchanged price target of $5.

TODAY'S FREE FLY STORIES

EFC

Ellington Financial

$18.79

0.01 (0.05%)

20:29
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HD

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1.64 (0.69%)

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$111.25

-0.86 (-0.77%)

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Notable companies reporting before tomorrow's open »

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ACY

AeroCentury

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-0.66 (-16.62%)

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MYOV

Myovant Sciences

$6.02

-0.14 (-2.27%)

19:29
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INVH

Invitation Homes

$29.95

-0.04 (-0.13%)

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Invitation Homes CEO sells 70K shares of common stock »

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BA

Boeing

$369.50

-2.05 (-0.55%)

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Southwest

$57.77

-0.03 (-0.05%)

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$369.50

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GBDC

Golub Capital

$17.79

0.045 (0.25%)

18:42
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Upgrade
Golub Capital rating change at Keefe Bruyette »

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GM

General Motors

$36.62

-0.25 (-0.68%)

, TM

Toyota

$143.53

-0.76 (-0.53%)

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Periodicals
CA to halt purchase of GM, Toyota, Fiat Chrysler vehicles, Reuters reports »

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GM

General Motors

$36.62

-0.25 (-0.68%)

TM

Toyota

$143.53

-0.76 (-0.53%)

FCAU

Fiat Chrysler

$15.63

-0.39 (-2.43%)

NSANY

Nissan

$0.00

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CRMT

America's Car-Mart

$90.88

3.22 (3.67%)

, WUBA

58.com

$50.26

-1.35 (-2.62%)

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CRMT

America's Car-Mart

$90.88

3.22 (3.67%)

WUBA

58.com

$50.26

-1.35 (-2.62%)

BILI

Bilibili

$16.39

-0.32 (-1.92%)

SAEX

SAExploration

$1.51

-0.05 (-3.21%)

CLVS

Clovis

$7.05

0.68 (10.68%)

NOW

ServiceNow

$266.56

6.65 (2.56%)

OKTA

Okta

$121.21

3.76 (3.20%)

SPLK

Splunk

$122.64

3.49 (2.93%)

WWD

Woodward

$113.64

-1.15 (-1.00%)

KRNT

Kornit Digital

$33.07

-1.13 (-3.30%)

ASH

Ashland

$78.65

0.03 (0.04%)

VNET

21Vianet

$8.28

0.23 (2.86%)

DHT

DHT Holdings

$7.52

-0.2 (-2.59%)

KRTX

Karuna Therapeutics

$94.70

77.44 (448.67%)

EGHT

8x8, Inc.

$20.78

0.13 (0.63%)

I

Intelsat

$7.98

-5.42 (-40.45%)

PFGC

Performance Food Group

$46.09

-0.08 (-0.17%)

EFC

Ellington Financial

$18.79

0.01 (0.05%)

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LEVI

Levi Strauss

$17.06

-0.115 (-0.67%)

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Levi Strauss CEO: I believe in the importance of innovation »

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CSCO

Cisco

$45.17

0.07 (0.16%)

18:17
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Periodicals
Cisco sues former employees over claims of trade secret theft, Bloomberg says »

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ABBV

AbbVie

$88.71

0.07 (0.08%)

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AbbVie treatment of myelofibrosis granted FDA orphan status »

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  • 07

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PRQR

ProQR Therapeutics

$6.27

-0.64 (-9.26%)

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BILI

Bilibili

$16.39

-0.32 (-1.92%)

18:04
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Earnings
Bilibili sees Q4 revenue RMB1.93B-RMB1.98B »

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WUBA

58.com

$50.26

-1.35 (-2.62%)

18:03
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Earnings
58.com sees Q4 revenue up 12%-15% in RMB terms »

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BILI

Bilibili

$16.39

-0.32 (-1.92%)

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Bilibili reports average MAUs reached 127.9M in Q3 »

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WUBA

58.com

$50.26

-1.35 (-2.62%)

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Earnings
58.com reports Q3 adjusted EPS 96c, consensus 82c »

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BILI

Bilibili

$16.39

-0.32 (-1.92%)

18:01
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Earnings
Bilibili reports Q3 adjusted EPS (15c), consensus (14c) »

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  • 18

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DDOG

Datadog

$40.36

-0.33 (-0.81%)

, AMZN

Amazon.com

$1,752.70

15.21 (0.88%)

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Datadog announces support for AWS CloudFormation Registry and CLI »

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DDOG

Datadog

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AMZN

Amazon.com

$1,752.70

15.21 (0.88%)

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Conference/Events
Morgan Stanley analyst to hold an analyst/industry conference call »

Managing Director &…

GVA

Granite Construction

$26.50

-0.6 (-2.21%)

17:54
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Granite Construction awarded $14M airfield improvement project in California »

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ZS

Zscaler

$44.46

-1.37 (-2.99%)

, MSFT

Microsoft

$150.35

0.4 (0.27%)

17:51
11/18/19
11/18
17:51
11/18/19
17:51
Initiation
Zscaler, Microsoft initiated at DA Davidson »

Zscaler initiated with a…

ZS

Zscaler

$44.46

-1.37 (-2.99%)

MSFT

Microsoft

$150.35

0.4 (0.27%)

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OKTA

Okta

$121.21

3.76 (3.20%)

17:51
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11/18
17:51
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17:51
Upgrade
Okta rating change at DA Davidson »

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PANW

Palo Alto Networks

$248.50

1.465 (0.59%)

17:48
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17:48
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17:48
Initiation
Palo Alto Networks initiated at DA Davidson »

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CRWD

Crowdstrike

$57.06

-2.73 (-4.57%)

, AMZN

Amazon.com

$1,752.70

15.21 (0.88%)

17:47
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11/18
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17:47
Initiation
Crowdstrike, Amazon.com initiated at DA Davidson »

Crowdstrike valuation…

CRWD

Crowdstrike

$57.06

-2.73 (-4.57%)

AMZN

Amazon.com

$1,752.70

15.21 (0.88%)

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