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ABBV

AbbVie

$87.72

2.08 (2.43%)

11:20
11/12/19
11/12
11:20
11/12/19
11:20

AbbVie reports 'positive' data from Phase 2/3 SELECT-AXIS 1 trial

AbbVie announced positive data from the Phase 2/3 SELECT-AXIS 1 trial in which twice as many adult patients with active ankylosing spondylitis treated with RINVOQ achieved the primary endpoint of Assessment of SpondyloArthritis International Society 40 response at week 14 versus placebo. SELECT-AXIS 1 is the first trial to evaluate the efficacy and safety of RINVOQ in adult patients with active AS who are naive to biologic disease-modifying antirheumatic drugs and had inadequate response or intolerance to nonsteroidal anti-inflammatory drugs. Full results were presented today at the 2019 American College of Rheumatology/Association for Rheumatology Professionals Annual Meeting in Atlanta and have been published concurrently in The Lancet. RINVOQ, a JAK inhibitor discovered and developed by AbbVie, is being studied as a once-daily therapy in AS and multiple immune-mediated inflammatory diseases. "Ankylosing spondylitis is a chronic, progressive, inflammatory disease that causes pain and stiffness, primarily in the spine, starting in early adulthood," said Desiree van der Heijde, Professor, Leiden University Medical Center, the Netherlands. "Apart from biologics, there are limited options available for patients who have an inadequate response or contraindication to NSAIDs. The results of this study highlight the potential of RINVOQ as an additional treatment option for patients living with ankylosing spondylitis."

  • 07

    Dec

ABBV AbbVie
$87.72

2.08 (2.43%)

09/26/19
09/26/19
UPGRADE

Fly Intel: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Square (SQ) upgraded to Outperform from Market Perform at Wells Fargo analyst Timothy Willi saying the company's fundamentals remain strong while investor sentiment is "overly negative and close to inflecting." 2. Whirlpool (WHR) upgraded to Overweight from Neutral at JPMorgan with analyst Michael Rehaut saying he expects U.S. industry shipments to be more stable year-over-year through the end of 2019 and show "modest" growth in 2020. 3. Boston Beer (SAM) upgraded to Outperform from Market Perform at BMO Capital with analyst Amit Sharma saying Truly is "primed to capture" strong consumer demand and higher distribution/shelf space for hard seltzer. 4. AbbVie (ABBV) upgraded to Buy from Neutral at Citi with analyst Andrew Baum saying he believes AbbVie will "extract significant shareholder value" from Allergan's (AGN) franchises given its "strong commercial focus and patient/physician centricity." 5. Hologic (HOLX) upgraded to Buy from Neutral at BofA/Merrill with analyst Ivy Ma saying she sees the company being on "steadier footing with organic growth upside in FY20" thanks to its tuck-in acquisitions. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
10/10/19
STFL
10/10/19
NO CHANGE
Target $135
STFL
Buy
Reata Pharmaceuticals 'bold move' should be well received by Street, says Stifel
Stifel analyst Adam Walsh notes that in "a bold move" likely to be well received by the Street, Reata Pharmaceuticals (RETA) reacquired ex-U.S. rights to BARD, OMAV, and other Nrf2 activators from AbbVie (ABBV) for total deal consideration of $330M. Given AbbVie's lack of a significant renal franchise, the reacquisition of ex-U.S. BARD rights restores strategic flexibility to Reata and provides the opportunity to either find a more engaging development partner, go it alone ex-U.S., or sell the company outright, he contends. Further, the analyst believes the deal terms look "highly reasonable" relative to potential ex-U.S. BARD sales. Walsh has a Buy rating and $135 price target on Reata's shares.
10/30/19
WELS
10/30/19
UPGRADE
Target $20
WELS
Outperform
Wells Fargo upgrades Revance to Outperform, boosts target to $20
Wells Fargo analyst Jacob Hughes upgraded Revance Therapeutics (RVNC) to Outperform from Market Perform with a price target of $20, up from $12.50. After meeting with management, the analyst likes the setup for shares. Revance has a commercial-focused CEO with a history of shareholder value creation in aesthetics and a "catalyst rich" 12 months, Hughes tells investors in a research note. He believes the stock has "significant upside potential" and likes the cash pay nature of aesthetics. The multi-billion neurotoxins market will continue to expand, and disruption from the Allergan (AGN), AbbVie (ABBV) merger will create opportunities for Revance to take share, contends Hughes.
11/01/19
PIPR
11/01/19
NO CHANGE
Target $90
PIPR
Overweight
AbbVie price target raised to $90 from $81 at Piper Jaffray
Piper Jaffray analyst Christopher Raymond raised his price target for AbbVie to $90 from $81 saying this morning's Q3 results were stronger than anticipated. The stock in afternoon trading is up 3% to $81.70. While "there were puts and takes across the board," including Humira and Imbruvica upside along with a "big miss" for the hepatitis C virus franchise, AbbVie posted Q3 earnings and sales beats, Raymond tells investors a post-earnings research note. Combined with the announcement of the dividend getting a double-digit increase, the analyst continues to like the setup for the shares and remains a buyer with an Overweight rating.

TODAY'S FREE FLY STORIES

FATE

Fate Therapeutics

$13.64

0.07 (0.52%)

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STOK

Stoke Therapeutics

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AUTL

Autolus Therapeutics

$14.60

-0.18 (-1.22%)

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  • 09

    Dec

AGIO

Agios Pharmaceuticals

$40.93

0.81 (2.02%)

09:22
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  • 09

    Dec

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    Dec

ZIOP

Ziopharm

$5.16

0.06 (1.18%)

09:20
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  • 08

    Dec

TGTX

TG Therapeutics

$7.11

-0.57 (-7.42%)

09:18
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  • 09

    Dec

KPTI

Karyopharm

$16.30

-1.15 (-6.59%)

09:16
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09:16
Hot Stocks
Karyopharm says four posters will be presented at ASH »

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IPHA

Innate Pharma

$6.30

(0.00%)

09:13
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12/08
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09:13
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Innate Pharma reports long-term data from Phase III trial of Lumoxiti »

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REGN

Regeneron

$372.26

4.02 (1.09%)

09:11
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Regeneron reports initial data for REGN5458 in myeloma patients »

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  • 08

    Dec

BPMC

Blueprint Medicines

$78.50

3.92 (5.26%)

09:09
12/08/19
12/08
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09:09
Hot Stocks
Blueprint reports 77% overall response rate in 48 patients from Explorer trial »

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  • 08

    Dec

BPMC

Blueprint Medicines

$78.50

3.92 (5.26%)

09:06
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12/08
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09:06
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Blueprint announces initial data from Phase 2 Pioneer trial in mastocytosis »

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  • 08

    Dec

PCG

PG&E

$9.65

-0.13 (-1.33%)

08:12
12/08/19
12/08
08:12
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08:12
Periodicals
PG&E settlement threatens bondholders plan, WSJ reports »

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  • 07

    Jan

SYRS

Syros Pharmaceuticals

$4.60

-0.02 (-0.43%)

08:08
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  • 08

    Dec

ABBV

AbbVie

$86.97

0.3 (0.35%)

08:06
12/08/19
12/08
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RHHBY

Roche

$0.00

(0.00%)

08:03
12/08/19
12/08
08:03
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08:03
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Genentech reports data from two Phase III Venclexta studies in leukemia »

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  • 09

    Dec

  • 10

    Dec

  • 10

    Dec

  • 16

    Dec

ORTX

Orchard Therapeutics

$11.85

0.37 (3.22%)

07:59
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Orchard to present data from multiple programs at ASH meeting »

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SRRA

Sierra Oncology

$0.49

0.1035 (27.13%)

06:55
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06:55
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Sierra Oncology to hold an analyst and investor event »

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  • 08

    Dec

RUHN

Ruhnn

$6.19

-0.2 (-3.13%)

04:55
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Conference/Events
Ruhnn management to meet with Mizuho »

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  • 08

    Dec

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    Dec

SRRA

Sierra Oncology

$0.49

0.1035 (27.13%)

04:55
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Conference/Events
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  • 08

    Dec

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Conference/Events
Piper Jaffray biotech analysts to hold a KOL luncheon »

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MGTA

Magenta Therapeutics

$13.29

0.3 (2.31%)

19:31
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  • 07

    Dec

  • 07

    Dec

PFE

Pfizer

$38.29

0.26 (0.68%)

, BMY

Bristol-Myers

$59.94

0.435 (0.73%)

19:29
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PFE

Pfizer

$38.29

0.26 (0.68%)

BMY

Bristol-Myers

$59.94

0.435 (0.73%)

03/08/13
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  • 07

    Dec

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    Dec

UMRX

Unum Therapeutics

$0.70

0.0177 (2.61%)

19:25
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Unum Therapeutics announces Phase 1 clinical updates for T-cell therapies »

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  • 07

    Dec

MGTA

Magenta Therapeutics

$13.29

0.3 (2.31%)

19:25
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Conference/Events
Magenta Therapeutics to hold an investor and analyst event »

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  • 07

    Dec

  • 07

    Dec

AUTL

Autolus Therapeutics

$14.60

-0.18 (-1.22%)

19:23
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  • 07

    Dec

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    Dec

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