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HARP

Harpoon Therapeutics

$14.50

-0.22 (-1.49%)

, ABBV

AbbVie

$87.20

-1.82 (-2.04%)

05:38
11/21/19
11/21
05:38
11/21/19
05:38

Harpoon Therapeutics, AbbVie announce licensing, option collaboration

Harpoon Therapeutics (HARP) and AbbVie (ABBV) announced an exclusive worldwide option and license transaction for HPN217, Harpoon's B cell maturation antigen, or BCMA,-targeting Tri-specific T cell Activating Construct, or TriTAC, and an expansion of their existing discovery collaboration for up to six additional targets. These agreements build upon the discovery collaboration established by the two companies in October 2017 and are expected to advance and broaden the use of Harpoon's proprietary TriTAC platform. The TriTAC platform produces novel T cell engagers targeting both solid tumors and hematologic malignancies. Under the terms of the license and option agreement, Harpoon granted to AbbVie an option to license worldwide exclusive rights to HPN217. Harpoon will be responsible for development of HPN217 through Phase 1/2 clinical trials. Upon exercise of the option, AbbVie will conduct all future clinical development, manufacturing and commercialization activities. AbbVie may exercise its option to license HPN217 after completion of the Phase 1/2 clinical trial. The license and option agreement represents a potential transaction value of up to $510 million in upfront, option and milestone payments, plus royalties on global commercial sales. Under the terms of the expanded discovery collaboration agreement, AbbVie will receive worldwide exclusive rights to develop and commercialize two new TriTAC molecules engineered for two selected targets. AbbVie has the option to select up to four additional targets for a total of up to six new targets. For each selected target under the Amended Discovery agreement, Harpoon is eligible to receive up to $310 million in upfront and potential development, regulatory and commercial milestone payments, plus royalties on global commercial sales. Consistent with the existing discovery collaboration agreement, Harpoon and AbbVie will conduct certain initial research and discovery activities for each designated target, after which AbbVie will be solely responsible for further development and commercialization efforts.

HARP

Harpoon Therapeutics

$14.50

-0.22 (-1.49%)

ABBV

AbbVie

$87.20

-1.82 (-2.04%)

  • 04

    Dec

  • 07

    Dec

HARP Harpoon Therapeutics
$14.50

-0.22 (-1.49%)

03/05/19
ADAM
03/05/19
INITIATION
Target $24
ADAM
Buy
Harpoon Therapeutics initiated with a Buy at Canaccord
Canaccord analyst Arlinda Lee initiated Harpoon Therapeutics with a Buy as she sees solid prospects for it lead drug candidate TriTac, which engages T cells to harness the body's immune system to treat cancer and other diseases. Lee has a $24 price target on Harpoon Therapeutics shares.
04/22/19
BARD
04/22/19
INITIATION
Target $25
BARD
Outperform
Harpoon Therapeutics initiated with an Outperform at Baird
Baird analyst Michael Ulz started Harpoon Therapeutics with an Outperform rating and $25 price target.
05/24/19
SBSH
05/24/19
INITIATION
Target $23
SBSH
Buy
Harpoon Therapeutics assumed with a Buy at Citi
Citi analyst Yigal Nochomovitz assumed coverage of Harpoon Therapeutics with a Buy rating and lowered his price target for the shares to $23 from $25. The analyst sees potential for upside over the next 12 months from initial clinical data from lead drug HPN424 in prostate cancer and HPN536 in mesothelin positive cancers.
11/13/19
ROTH
11/13/19
INITIATION
Target $25
ROTH
Buy
Harpoon Therapeutics initiated with a Buy at Roth Capital
Roth Capital analyst Zegbeh Jallah initiated coverage of Harpoon Therapeutics with a Buy rating and $25 price target. The analyst likes Harpoon's modular, tri-specific T-cell targeting platform and the company's clinical strategy focusing on biomarker-selected patients that could allow for a faster path to approval. Harpoon has a next-generation tri-specific platform optimized for efficient tumor penetration, limited toxicity, and more convenient dosing, Jallah tells investors in a research note.
ABBV AbbVie
$87.20

-1.82 (-2.04%)

11/15/19
GUGG
11/15/19
NO CHANGE
Target $228
GUGG
Buy
BeiGene price target raised to $228 from $205 at Guggenheim
Guggenheim analyst Michael Schmidt raised his price target for BeiGene (BGNE) to $228 from $205 saying FDA approval of Brukinsa over three months ahead of the action date provides additional validation of the company's strategy and ability to execute. He thinks Brukinsa's label in mantle cell lymphoma indicates a "potentially best-in-class" product profile with "nuanced differences" compared to AstraZeneca's (AZN) Calquence and "significantly better" than AbbVie's (ABBV) Imbruvica. The analyst maintains a Buy rating on BeiGene shares.
11/19/19
UBSW
11/19/19
DOWNGRADE
Target $203
UBSW
Neutral
UBS downgrades Allergan to Neutral ahead of expected deal closure
UBS analyst Navin Jacob downgraded Allergan (AGN) to Neutral from Buy with a price target of $203, up from $189. Based on takeover terms and a $96 price target for AbbVie (ABBV), much of the upside is largely baked in to Allergan shares, Jacob tells investors in a research note. The analyst expects the deal to close in Q1 of 2020 and believes that the companies have sufficiently addressed possible anti-trust issues with the announced divestitures of Zenpep and Brazikumab.
11/19/19
UBSW
11/19/19
NO CHANGE
Target $96
UBSW
Buy
AbbVie price target raised to $96 from $79 at UBS
UBS analyst Navin Jacob raised his price target for AbbVie (ABBV) to $96 from $79 and continues to recommend the shares with a Buy rating. He believes Skyrizi's demand is accelerating and now expects $1B in annual sales by 2021. Further, AbbVie now expects Rinvoq to have 75% of covered lives by January 2020, which is much faster than expected, Jacob tells investors in a research note. The growth drivers and the company's underlying cash generation "provides assurance" that AbbVie can weather the Humira loss of exclusivity in 2023, contends Jacob.
11/20/19
SBSH
11/20/19
NO CHANGE
Target $98
SBSH
Buy
AbbVie price target raised to $98 from $90 at Citi
Citi analyst Andrew Baum raised his price target for AbbVie (ABBV) to $98 from $90 and keeps a Buy rating on the shares. The analyst believes AbbVie will trade near-term above its $92 intrinsic value as Skyrizi and Rinvoq forecasts are revised upwards. In the near-term, the market will likely choose to focus on ongoing Skyrizi upgrades and Allergan (AGN) synergies and disregard mid and long-term risks to chronic lymphocytic leukemia estimates, Baum tells investors in a research note. The analyst's "bull-case valuation" is $119 per share.

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ATNX

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ACB

Aurora Cannabis

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Cronos Group

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BDSI

BioDelivery Sciences

$6.40

-0.065 (-1.01%)

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BioDelivery Sciences management to meet with SunTrust »

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AOBC

American Outdoor Brands

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Roth Capital to hold a conference »

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LOVE

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VERI

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WTER

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WFT

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CNC

Centene

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LEA

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OAS

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SWN

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UNT

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FTR

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PLAN

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WPX

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HLIT

Harmonic

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HZNP

Horizon Pharma

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AMRN

Amarin

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THMO

ThermoGenesis

$2.88

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AMRN

Amarin

$24.12

1.12 (4.87%)

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QTNT

Quotient

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ARWR

Arrowhead

$66.47

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OAS

Oasis Petroleum

$2.68

-0.295 (-9.93%)

, SWN

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$2.00

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Oasis, Southwestern to replace Unit Corp., Frontier in S&P 600 at open on 12/23 »

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OAS

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$2.68

-0.295 (-9.93%)

SWN

Southwestern Energy

$2.00

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UNT

Unit Corp.

$0.83

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FTR

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AMRN

Amarin

$24.12

1.12 (4.87%)

17:24
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LOPE

Grand Canyon

$89.24

-0.86 (-0.95%)

, LEA

Lear

$129.43

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LOPE

Grand Canyon

$89.24

-0.86 (-0.95%)

LEA

Lear

$129.43

-0.84 (-0.64%)

OAS

Oasis Petroleum

$2.68

-0.295 (-9.93%)

SWN

Southwestern Energy

$2.00

-0.12 (-5.66%)

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