Breaking News Instant updates and real-time market news.

NK

NantKwest

$1.51

-0.195 (-11.47%)

16:06
12/02/19
12/02
16:06
12/02/19
16:06

NantKwest announces 'promising' data from first six patients in QUILT trial

NantKwest announced promising safety data generated from the first six patients in its QUILT-3.064 trial. The first-in-human study evaluated the safety and preliminary efficacy of the Company's first-in-class, tumor-targeted PD-L1.t-haNK cell therapy in patients with locally advanced or metastatic solid tumors. "The unique dual-targeting of PD-L1.t-haNK to both PD-L1 expressing tumors and therapeutic monoclonal antibodies has the potential to be transformative to the treatment of advanced solid tumors with cell-based therapies," said Dr. Patrick Soon-Shiong, the Chairman and CEO of NantKwest. "PD-L1.t-haNK is a cryopreserved, off-the-shelf product that can rapidly deliver treatment to patients in an outpatient setting while avoiding the extensive manufacturing delays associated with autologous CAR-T therapies. We look forward to reporting full study results from the phase 1 cohort and moving toward a recommended phase 2 dose. We continue to advance our innovative cell therapies such as PD-L1.t-haNK in combination with ImmunityBio's N-803, an IL-15 superagonist that is designed to stimulate the activation and proliferation of the patient's own NK cells to maximize the potential of immunogenic cell death to treat cancer," continued Soon-Shiong. NantKwest and a wholly owned subsidiary of ImmunityBio have entered into an exclusive collaboration agreement to co-develop NantKwest's proprietary off-the-shelf NK platforms in combination with N-803. John Lee, M.D., Clinical Senior Vice President at NantKwest, said, "We are highly encouraged by the early safety results with PD-L1.t-haNK in a patient population with advanced, difficult to treat solid tumors. All patients were able to be infused in the outpatient setting without any reported cytokine toxicities or immune related adverse events. NantKwest's approach has been designed to overcome the challenges and limitations typically seen when treating solid tumors with CAR-T and other immunotherapy approaches and I look forward to progressing our studies to advance this innovative new approach to cancer therapy."

NK NantKwest
$1.51

-0.195 (-11.47%)

05/30/19
SBSH
05/30/19
DOWNGRADE
SBSH
Sell
NantKwest downgraded to Sell from Neutral at Citi
05/31/19
SBSH
05/31/19
DOWNGRADE
Target $0.8
SBSH
Sell
Citi downgrades NantKwest to Sell with 80c price target
Citi analyst Joel Beatty last night downgraded NantKwest to Sell from Neutral and cut his price target for the shares to 80c from $1.25. The analyst believes the most likely scenario is that NantKwest's pipeline shows "little signs of progress" over the next 12 months, while continuing operating cash burn. Clinical trial activity involving the company's agents may be decreasing, at least temporarily, Beatty tells investors in a research note.

TODAY'S FREE FLY STORIES

AMBA

Ambarella

$54.84

2.33 (4.44%)

13:05
12/11/19
12/11
13:05
12/11/19
13:05
Options
Ambarella call volume above normal and directionally bullish »

Bullish option flow…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 08

    Jan

FB

Facebook

$201.00

0.1 (0.05%)

, ICE

IntercontinentalExchange

$92.63

0.31 (0.34%)

12:56
12/11/19
12/11
12:56
12/11/19
12:56
Periodicals
Nasdaq on track to beat NYSE in IPOs for first time since 2012, WSJ says »

Companies are on pace to…

FB

Facebook

$201.00

0.1 (0.05%)

ICE

IntercontinentalExchange

$92.63

0.31 (0.34%)

NDAQ

Nasdaq

$104.36

-0.26 (-0.25%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 11

    Dec

  • 29

    Jan

  • 06

    Feb

12:55
12/11/19
12/11
12:55
12/11/19
12:55
Conference/Events
UBS retail analysts to hold an analyst/industry conference call »

Retail Analysts…

SGEN

Seattle Genetics

$111.78

-2.19 (-1.92%)

12:53
12/11/19
12/11
12:53
12/11/19
12:53
Recommendations
Seattle Genetics analyst commentary  »

Seattle Genetics data…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 15

    Mar

TWTR

Twitter

$30.16

0.31 (1.04%)

, SQ

Square

$65.52

-0.3 (-0.46%)

12:48
12/11/19
12/11
12:48
12/11/19
12:48
On The Fly
#SocialStocks: YouTube updates harassment policy, Snapchat 'deepfake' GIFs »

Welcome to…

TWTR

Twitter

$30.16

0.31 (1.04%)

SQ

Square

$65.52

-0.3 (-0.46%)

FB

Facebook

$201.03

0.13 (0.06%)

AMZN

Amazon.com

$1,738.68

-0.47 (-0.03%)

SNAP

Snap

$14.15

0.065 (0.46%)

GOOGL

Alphabet Class A

$1,342.74

-0.3 (-0.02%)

GOOG

Alphabet

$1,344.23

-0.27 (-0.02%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 06

    Feb

  • 26

    Feb

CIEN

Ciena

$35.15

0.45 (1.30%)

, LOVE

Lovesac

$14.52

0.08 (0.55%)

12:48
12/11/19
12/11
12:48
12/11/19
12:48
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

CIEN

Ciena

$35.15

0.45 (1.30%)

LOVE

Lovesac

$14.52

0.08 (0.55%)

VERU

Veru

$2.27

-0.03 (-1.30%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 11

    Dec

  • 12

    Dec

  • 12

    Dec

  • 12

    Dec

  • 17

    Dec

  • 19

    Dec

LULU

Lululemon

$232.23

2.67 (1.16%)

, NDSN

Nordson

$165.56

-0.19 (-0.11%)

12:48
12/11/19
12/11
12:48
12/11/19
12:48
Earnings
Notable companies reporting after market close »

Notable companies…

LULU

Lululemon

$232.23

2.67 (1.16%)

NDSN

Nordson

$165.56

-0.19 (-0.11%)

OXM

Oxford Industries

$74.50

-1.46 (-1.92%)

MESA

Mesa Air

$9.04

-0.04 (-0.44%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 11

    Dec

  • 11

    Dec

  • 11

    Dec

  • 12

    Dec

CSCO

Cisco

$44.29

0.18 (0.41%)

, CMCSA

Comcast

$42.04

-0.73 (-1.71%)

12:45
12/11/19
12/11
12:45
12/11/19
12:45
Hot Stocks
Cisco announces 'Internet for the Future' strategy »

Cisco (CSCO) unveiled…

CSCO

Cisco

$44.29

0.18 (0.41%)

CMCSA

Comcast

$42.04

-0.73 (-1.71%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 11

    Dec

  • 12

    Dec

  • 08

    Jan

  • 12

    Feb

ADI

Analog Devices

$115.90

1.48 (1.29%)

12:45
12/11/19
12/11
12:45
12/11/19
12:45
Options
Analog Devices call volume above normal and directionally bullish »

Bullish option flow…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 17

    Dec

  • 18

    Dec

SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$313.73

0.18 (0.06%)

12:45
12/11/19
12/11
12:45
12/11/19
12:45
Hot Stocks
Gundlach says in next recession, U.S. will be worst stock market in world »

DoubleLine CEO Jeffrey…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$313.73

0.18 (0.06%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

12:45
12/11/19
12/11
12:45
12/11/19
12:45
General news
FOMC forecast revisions »

FOMC forecast revisions…

PLCE

Children's Place

$54.72

-15.95 (-22.57%)

12:44
12/11/19
12/11
12:44
12/11/19
12:44
Downgrade
Children's Place rating change  »

Children's Place…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 11

    Dec

SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$313.73

0.18 (0.06%)

12:41
12/11/19
12/11
12:41
12/11/19
12:41
Hot Stocks
Gundlach says Hillary Clinton would be strongest Democratic candidate »

DoubleLine CEO Jeffrey…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$313.73

0.18 (0.06%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

CNMD

Conmed

$112.16

(0.00%)

12:41
12/11/19
12/11
12:41
12/11/19
12:41
Hot Stocks
Conmed VP John Kennedy sells almost $700K in company shares »

Conmed VP John Kennedy…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$313.71

0.16 (0.05%)

12:40
12/11/19
12/11
12:40
12/11/19
12:40
Hot Stocks
Gundlach says Trump winning reelection more positive than negative for market »

DoubleLine CEO Jeffrey…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$313.71

0.16 (0.05%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$313.70

0.15 (0.05%)

12:40
12/11/19
12/11
12:40
12/11/19
12:40
Hot Stocks
Gundlach says Elizabeth Warren is 'done' amid collapsing poll numbers »

DoubleLine CEO Jeffrey…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$313.70

0.15 (0.05%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

ETFC

E-Trade

$45.57

0.2 (0.44%)

12:39
12/11/19
12/11
12:39
12/11/19
12:39
Hot Stocks
E-Trade says rumor that company has been approached 'patently false' »

Says the rumor that the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 11

    Dec

  • 18

    Dec

  • 26

    Feb

SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$313.72

0.17 (0.05%)

12:38
12/11/19
12/11
12:38
12/11/19
12:38
Hot Stocks
Gundlach says Bloomberg 'has no chance' to win nomination »

DoubleLine CEO Jeffrey…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$313.72

0.17 (0.05%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$313.75

0.2 (0.06%)

12:36
12/11/19
12/11
12:36
12/11/19
12:36
Hot Stocks
Gundlach says his 'base case' is President Trump wins reelection »

DoubleLine CEO Jeffrey…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$313.75

0.2 (0.06%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

NSRGY

Nestle

$0.00

(0.00%)

12:33
12/11/19
12/11
12:33
12/11/19
12:33
Hot Stocks
Nestle to sell U.S. ice cream business to Froneri JV in $4B transaction »

Nestle announced that it…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

LOGM

LogMeln

$79.62

5.66 (7.65%)

12:26
12/11/19
12/11
12:26
12/11/19
12:26
Periodicals
PE firms in talks to buy LogMeln, Bloomberg says »

Private equity firm…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

ANF

Abercrombie & Fitch

$16.68

-1.1 (-6.19%)

12:25
12/11/19
12/11
12:25
12/11/19
12:25
Options
Abercrombie & Fitch call volume above normal and directionally bullish »

Bullish option flow…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

NSRGY

Nestle

$0.00

(0.00%)

12:23
12/11/19
12/11
12:23
12/11/19
12:23
Periodicals
Nestle close to selling U.S. ice cream unit to Froneri JV, Bloomberg says »

The deal would value the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SPX

S&P 500

$0.00

(0.00%)

, SPY

SPDR S&P 500 ETF Trust

$313.78

0.23 (0.07%)

12:22
12/11/19
12/11
12:22
12/11/19
12:22
Hot Stocks
Gundlach says now is time to exit corporate bond market »

DoubleLine CEO Jeffrey…

SPX

S&P 500

$0.00

(0.00%)

SPY

SPDR S&P 500 ETF Trust

$313.78

0.23 (0.07%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

$NSD

NASDAQ Market Internals

$0.00

(0.00%)

12:17
12/11/19
12/11
12:17
12/11/19
12:17
Technical Analysis
NASDAQ market internals summary »

Volume is average for…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.