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JNJ

Johnson & Johnson

$140.36

0.79 (0.57%)

07:51
12/07/19
12/07
07:51
12/07/19
07:51

Janssen announces initial results from Phase 1b/2 multiple myeloma study

Janssen Pharmaceutical Companies of Johnson & Johnson announced initial results from the Phase 1b/2 Cartitude-1 study evaluating the efficacy and safety of JNJ-68284528, an investigational B cell maturation antigen-directed chimeric antigen receptor T cell therapy being evaluated in the treatment of patients with relapsed or refractory multiple myeloma. The study enrolled patients who have received at least three prior lines of therapy or are double refractory to a proteasome inhibitor and an immunomodulatory drug; have received a PI, IMiD and an anti-CD38 antibody; and who progressed on or within 12 months of their last line of therapy. Results from the Phase 1b portion of the study showed "early and deep responses" among 29 patients with a median of five prior multiple myeloma treatment regimens treated with JNJ-4528, with 100% of patients achieving a response at a median six-month follow-up, Janssen said. The overall response rate included 69% of patients achieving a complete response or better; 86% of patients achieving a very good partial response or better; and 14% of patients achieving a partial response. In addition, 100% of evaluable patients achieved early minimal residual disease-negative disease status at day 28 post-infusion. At the six-month follow-up, 27 of 29 patients were progression-free. Based on the Phase 1b results, a recommended Phase 2 dose of 0.75x106 CAR+ viable T cells/kg was confirmed, the company added. The most common adverse events observed in the study were cytokine release syndrome, neutropenia, anemia and thrombocytopenia.

  • 07

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    Jan

JNJ Johnson & Johnson
$140.36

0.79 (0.57%)

10/30/19
MSCO
10/30/19
NO CHANGE
MSCO
Morgan Stanley says J&J talc test 'not an all clear,' but incremental positive
Morgan Stanley analyst David Lewis noted that Johnson & Johnson announced that its independent testing concluded no presence of asbestos in the company's previously recalled baby powder, though the FDA subsequently stated, "They would say the product is free of asbestos based on their testing, and we would say the opposite for that sample." Though the FDA is standing behind its test, Lewis doesn't think this suggests a contentious disagreement, but rather a statement of fact for respective testing. The analyst, who said that he has more work to do to understand the results and protocols, said this news is "not an all clear," but it is an incremental positive.
11/19/19
CANT
11/19/19
INITIATION
Target $160
CANT
Overweight
Johnson & Johnson initiated with an Overweight at Cantor Fitzgerald
Cantor Fitzgerald analyst Louise Chen initiated coverage of Johnson & Johnson with an Overweight rating and $160 price target.
11/20/19
CANT
11/20/19
INITIATION
Target $160
CANT
Overweight
Cantor Fitzgerald starts Johnson & Johnson with Overweight, $160 price target
Cantor Fitzgerald analyst Louise Chen last night initiated coverage of Johnson & Johnson with an Overweight rating and $160 price target. Upwards earnings revisions to J&J's Pharma business and multiple expansion, driven by diminishing headlines risks from talc and opioids, should move the shares higher, Chen tells investors in a research note. She points out that Johnson & Johnson has reported eight consecutive years of pharma operational sales growth of 8.9% annually, about twice as fast as the global market. The analyst also thinks the company's liabilities from talc and opioids are manageable with its cash balance, as well as its cash flow from operations.
11/20/19
11/20/19
INITIATION

Fly Intel: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Johnson & Johnson (JNJ) initiated with an Overweight at Cantor Fitzgerald. 2. Brink's (BCO) initiated with a Buy at Goldman Sachs. 3. KLA-Tencor (KLAC) initiated with a Buy at Nomura Instinet. 4. NexTier Oilfield (NEX) initiated with a Buy at Citi. 5. Carrols Restaurant (TAST) initiated with a Buy at Craig-Hallum. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

TLGT

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TSM

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KKR

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$31.20

0.7 (2.30%)

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KKR

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$31.20

0.7 (2.30%)

APO

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$50.35

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ARES

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BX

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$60.79

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CG

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$33.30

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HLNE

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SPCE

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GOOG

Alphabet

$1,480.28

28.34 (1.95%)

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GOOG

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$1,480.28

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NFLX

Netflix

$339.56

0.89 (0.26%)

CMCSK

Comcast

$0.00

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CMCSA

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$47.48

0.62 (1.32%)

GOOGL

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$1,479.12

29.29 (2.02%)

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JWN

Nordstrom

$40.34

-0.15 (-0.37%)

, WMT

Walmart

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JWN

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WMT

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CSPR

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BA

Boeing

$324.11

-7.89 (-2.38%)

, DDAIF

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$0.00

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DDAIF

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$0.00

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FCAU

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$13.76

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VWAGY

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$0.00

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FSLR

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$53.51

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AAPL

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$318.66

3.33 (1.06%)

DQ

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$53.61

-0.025 (-0.05%)

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SPOT

Spotify

$148.20

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CE

Celanese

$117.54

-0.53 (-0.45%)

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BYND

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DBD

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IEF

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IEF

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SHY

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SPY

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SLV

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$16.82

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FXE

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UBSFY

Ubisoft

$0.00

(0.00%)

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IMVT

Immunovant

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TBLT

ToughBuilt

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MYO

Myomo

$0.32

0.0062 (1.98%)

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  • 21

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SRRA

Sierra Oncology

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  • 21

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SRNE

Sorrento Therapeutics

$4.26

-0.15 (-3.40%)

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AKER

Akers Biosciences

$3.45

-0.1 (-2.82%)

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ECA

Encana

$4.09

-0.18 (-4.22%)

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  • 29

    Jan

MBRX

Moleculin Biotech

$0.96

0.0122 (1.29%)

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VOD

Vodafone

$20.07

-0.225 (-1.11%)

, BT

BT Group

$0.00

(0.00%)

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VOD

Vodafone

$20.07

-0.225 (-1.11%)

BT

BT Group

$0.00

(0.00%)

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16:30
01/17/20
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16:30
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16:30
Options
Preliminary option volume of 28.7M today »

Preliminary option volume…

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