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RHHBY

Roche

$0.00 /

+ (+0.00%)

09:09
12/07/19
12/07
09:09
12/07/19
09:09

Genentech announces new data on CD20-CD3 T-cell in Hodgkin's lymphoma

Genentech, a member of the Roche Group, announced new data on two investigational CD20-CD3 T-cell engaging bispecific antibodies, mosunetuzumab and CD20-TCB, in people with relapsed or refractory B-cell non-Hodgkin's lymphoma. Results from the Phase I/Ib GO29781 study of mosunetuzumab, including data from people previously treated with chimeric antigen receptor T-cell therapy, will be presented at the 61st American Society of Hematology 2019 Annual Meeting. The GO29781 study evaluated mosunetuzumab in patients with R/R NHL, including patients who have relapsed following, or are resistant to, CAR T-cell therapy. Results from this dose-escalation study showed "encouraging efficacy" with an objective response rate of 62.7% in slow-growing NHL and 37.1% in aggressive NHL. Additionally, data demonstrated a complete response rate of 43.3% in slow-growing NHL and 19.4% in aggressive NHL. CRs showed durability, with 82.8% of patients with slow-growing NHL remaining in remission up to 26 months off initial treatment and 70.8% of patients with aggressive NHL, remaining in remission up to 16 months off initial treatment, the company added. Of the participants who received prior CAR T-cell therapy, the ORR was 38.9%, and 22.2% achieved a CR. Adverse reactions included cytokine release syndrome in 28.9% of patients with 20.0% at Grade 1 and 1.1% at Grade 3. Grade 3 neurological adverse events occurred in 3.7% of patients, Genentech said.

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RHHBY Roche
$0.00 /

+ (+0.00%)

11/19/19 SVB Leerink
Dicerna price target raised to $30 from $26 at SVB Leerink
11/14/19 William Blair
William Blair says Ionis fairly valued on Spinraza headwinds
11/01/19 H.C. Wainwright
Dicerna HBV deal earlier, on better terms than expected, says H.C. Wainwright
11/01/19 SVB Leerink
Dicerna price target raised to $26 from $22 at SVB Leerink

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Hot Stocks
Marriott: Guidance doesn't reflect any impact from coronavvirus  10:12
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MAR

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-2.33 (-1.94%)

 
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Put spread sale in Financial Sector ETF rolls winner down in strike » 10:10
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Financial Select Sector

$27.90 /

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Options
Zoom Video Communications call volume above normal and directionally bullish » 10:05
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ZM

Zoom Video

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+4.61 (+4.32%)

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Conference/Events
Morgan Stanley tobacco analysts to hold an analyst/industry conference call » 10:03
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British American Tobacco

$41.14 /

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Altria Group

$41.95 /

-0.18 (-0.43%)

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Marriott CEO says 'still a great deal we do not know' about coronavirus » 10:03
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MAR

Marriott

$115.13 /

-4.75 (-3.96%)

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Moderna trading resumes  10:03
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Moderna

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+5.52 (+18.92%)

 
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General news
Pending Home Sales Index data reported » 10:02
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Virgin Galactic falls -21.7% » 10:00
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SPCE

Virgin Galactic

$22.53 /

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Anaplan falls -22.0% » 10:00
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PLAN

Anaplan

$45.29 /

-12.68 (-21.87%)

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EQT Midstream Partners falls -24.1% » 10:00
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EQM

EQT Midstream Partners

$16.28 /

-5.315 (-24.62%)

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Britannia Bulk rises 13.0% » 10:00
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DWT

Britannia Bulk

$7.45 /

+0.92 (+14.09%)

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Teladoc rises 19.3% » 10:00
02/27/20
02/27
10:00
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TDOC

Teladoc

$139.51 /

+22.625 (+19.36%)

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Gain Capital rises 66.0% » 10:00
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GCAP

Gain Capital

$5.87 /

+2.285 (+63.83%)

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Recommendations
Stifel reiterates Buy on Zogenix as FDA extends Dravet PDUFA » 09:58
02/27/20
02/27
09:58
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ZGNX

Zogenix

$19.35 /

-6.695 (-25.71%)

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Moderna trading halted, volatility trading pause  09:58
02/27/20
02/27
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MRNA

Moderna

$34.82 /

+5.65 (+19.37%)

 
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Options
Carnival put volume heavy and directionally bearish » 09:55
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02/27
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CCL

Carnival

$31.82 /

-1.33 (-4.01%)

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Options
Early notable gainers among liquid option names on February 27th » 09:55
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PDCO

Patterson Companies

$24.11 /

+1.455 (+6.42%)

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$38.72 /

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$23.96 /

-0.16 (-0.66%)

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Apache

$24.20 /

-0.245 (-1.00%)

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Today's U.S. GDP report » 09:55
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AB InBev says impact of COVID-19 reflected in current guidance » 09:53
02/27/20
02/27
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BUD

AB InBev

$60.95 /

-5.4 (-8.14%)

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Capital One ups Physicians Realty to Overweight, says revaluation warranted » 09:50
02/27/20
02/27
09:50
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09:50
DOC

Physicians Realty Trust

$20.27 /

-0.03 (-0.15%)

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Vir jumps 75% to $61.09 despite Baird downgrade as coronavirus spreads  09:50
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VIR

Vir Biotechnology

$62.09 /

+27.14 (+77.65%)

 
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Conference/Events
Five9 management to meet with JPMorgan » 09:48
02/27/20
02/27
09:48
02/27/20
09:48
FIVN

Five9

$74.16 /

+0.12 (+0.16%)

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Virgin Galactic falls -16.1% » 09:47
02/27/20
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SPCE

Virgin Galactic

$28.69 /

-4.96 (-14.74%)

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Continental Resources falls -28.4% » 09:47
02/27/20
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09:47
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CLR

Continental Resources

$15.01 /

-5.78 (-27.81%)

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China Online Education trading resumes  09:47
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02/27
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COE

China Online Education

$37.48 /

+2.75 (+7.92%)

 
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