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SGMO

Sangamo

$11.65 /

+0.05 (+0.43%)

, PFE

Pfizer

$38.29 /

+0.26 (+0.68%)

09:14
12/07/19
12/07
09:14
12/07/19
09:14

Sangamo, Pfizer announce follow-up results from Phase 1/2 hemophilia A.study

Sangamo Therapeutics (SGMO) and Pfizer (PFE) announced updated follow-up results from the Phase 1/2 Alta study evaluating investigational SB-525 gene therapy in patients with severe hemophilia A. The data showed that SB-525 was generally well tolerated and demonstrated sustained increased Factor VIII levels following treatment with SB-525 through to 44 weeks, the extent of follow-up for the longest treated patient in the 3e13 vg/kg dose cohort, the companies said.. Data from 11 patients treated with SB-525 will be featured in a poster presentation today at the Annual Meeting of the American Society of Hematology. In the 3e13 vg/kg dose cohort, patients achieved normal range FVIII activity within 5-7 weeks of treatment with SB-525, the companies added. "We are pleased with the progress that we have made in progressing SB-525 gene therapy toward a Phase 3 registrational study, including enrolling the first patient in the 6-month lead-in study. We expect to dose the first patient in the Phase 3 registrational study in 2020," said Seng Cheng, Senior Vice President and Chief Scientific Officer of Pfizer's Rare Diseases Research Unit. "We continue to believe that if the observed safety and efficacy results are sustained, this gene therapy has the potential to transform the treatment paradigm of severe hemophilia A."

SGMO

Sangamo

$11.65 /

+0.05 (+0.43%)

PFE

Pfizer

$38.29 /

+0.26 (+0.68%)

  • 07

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SGMO Sangamo
$11.65 /

+0.05 (+0.43%)

08/26/19
Fly Intel: Top five analyst initiations
08/26/19 H.C. Wainwright
Sangamo initiated with a Buy at H.C. Wainwright
07/26/19 Canaccord
Homology Medicines selloff yesterday a buying opportunity, says Canaccord
07/12/19 Jefferies
Sangamo should be bought at current share levels, says Jefferies
PFE Pfizer
$38.29 /

+0.26 (+0.68%)

11/25/19 Piper Sandler
Opko Health initiated with an Overweight at Piper Jaffray
11/12/19 Piper Sandler
Time to dismiss Solid Biosciences as Sarepta competitor, says Piper Jaffray
11/06/19 Piper Sandler
Ionis Pharmaceuticals price target lowered to $70 from $75 at Piper Jaffray
11/01/19 Raymond James
Intellia Therapeutics upgraded to Outperform at Raymond James

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Conference/Events
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Technical Analysis
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Hot Stocks
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Options
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General news
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Periodicals
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General news
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Recommendations
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Options
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A

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Periodicals
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Earnings
Southern Company sees Q1 EPS 72c, consensus 76c  12:36
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SO

Southern Company

$68.75 /

+0.11 (+0.16%)

 
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Earnings
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+0.11 (+0.16%)

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